#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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See #NephJC Influencers/Analytics.

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Krithika Mohan @krithicism
Looking forward to tomorrow's #NephJC chat on the PREDNOS trial. It would be great if all our Paeds colleagues could join us !!
Tom Forbes @kidney_tom
@drjosflynn @KidneyCathy @louise_oni @KidneyLoren @YincentTse @ASPNeph @bt_scanlan @MijkBoyle @BAPNnephrology @StotterMD @NephJC @munrocb @ISNWCN @jeanniejampots @PaddyPfitzp @gratefull080504 @IrwinGill @HossaiGul @IkeOkafor16 @SwastiThinks @asouth_neph @menonshina @EBlanchettePeds @ingelfinger @pedsnephrology @profnickwebb @IPNA_PedNeph @kidsbeansdoc @kidneytweets @MedEdMahan @davidsas1 @kidneyomicsamps @Renaltubules @PattySeoMayerMD @BabyBeanDoc @zjmodi @Aussiekidney @aviva_goldberg @chishti_aftab I’d love to join but #NephJC always clashes with my clinic.
Guillermo Lopez C @memoalexlope
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
otepathology @otepathology
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Dr Maryam Khosravi @_Dr_MK
RT @KidneyCathy: This is SUCH an exciting week for all paed nephrologists - we will be discussing nephrotic syndrome and the recent #PREDNO
Sony Mandal @SonyMandal7
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Swapnil Hiremath, MD, MPH @hswapnil
RT @krithicism: Looking forward to tomorrow's #NephJC chat on the PREDNOS trial. It would be great if all our Paeds colleagues could join u…
A. Y. H., MD. @AYHashimYT
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Pathology @mvmd0908
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
pembeoltulu @pembeoltulu
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Brian Stotter, MD @StotterMD
@drjosflynn @KidneyCathy @kidney_tom @louise_oni @KidneyLoren @YincentTse @ASPNeph @bt_scanlan @MijkBoyle @BAPNnephrology @NephJC @munrocb @ISNWCN @jeanniejampots @PaddyPfitzp @gratefull080504 @IrwinGill @HossaiGul @IkeOkafor16 @SwastiThinks @asouth_neph @menonshina @EBlanchettePeds @ingelfinger @pedsnephrology @profnickwebb @IPNA_PedNeph @kidsbeansdoc @kidneytweets @MedEdMahan @davidsas1 @kidneyomicsamps @Renaltubules @PattySeoMayerMD @BabyBeanDoc @zjmodi @Aussiekidney @aviva_goldberg @chishti_aftab #nephJC tonight 9pm EST/6pm PST I believe
Luis Enrique Alvarez @LuisEnr80631682
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
ياسين المشرقي (yasin Almishragi) @YAlmishragi
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Dulce López @Dulce_LS
RT @irmaerana: Excelente imagen de una nefropatía membranosa. #patomorfo2 #RenalPath https://t.co/8nFy4s03QA
Eric Au @ericau
RT @krithicism: Looking forward to tomorrow's #NephJC chat on the PREDNOS trial. It would be great if all our Paeds colleagues could join u…
Wisit661 @wisit661
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Nephrology Jrnl Club @NephJC
RT @krithicism: Looking forward to tomorrow's #NephJC chat on the PREDNOS trial. It would be great if all our Paeds colleagues could join u…
Kevin J. Fowler @gratefull080504
I will make every effort to be at #nephJC tonight
Jung Hoon Son, M.D. @junghoon_sonMD
CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions like CKD is what healthcare needs. Tracking ~8000 patients in one shot - thanks to @flowingdata @pulse_data #datascience #healthcare #nephrology #askasn #nephjc https://t.co/mE3Ht96Ac0
Suresh M @yemtweet
@enherts The East of England Renal Network Meeting at Chesterford Research Park; thanks to Rachel and CRN meeting for organising! Sarah and Lisa organised a fantastic SpR Training day as part of this. KQuiP was discussed and we have a plan😉 #nephjc https://t.co/QFlKQBpKGU
soda_troubles @set_fortess
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Arvind Canchi 🇮🇳 @arvindcanchi
Nephrologist Handwriting. Exhibit number 10. A class apart.
Marcelo Tavares @pednephrol
RT @BAPNnephrology: Calling all paeds nephrology professionals - this week's #nephjc is going Paediatric and where better to start than the…
sana tabish @sanatabish6
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
BAPN @BAPNnephrology
Timezones below #nephjc #PREDNOS @ADC_BMJ @ArchivesEandP @RCPCHtweets
nickwebb @profnickwebb
Thank you. Will try my very best to join the discussion at 2200CET tomorrow. Not done this before so please be gentle!
Swapnil Hiremath, MD, MPH @hswapnil
Finally! Getting ready for upcoming #NephJC book club (July 23/24) https://t.co/JZYJYGsP0p
Alex Chang, MD, MS @alexchangmd
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Jeffrey Pearson @pearsonjeffrey
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Joseph Flynn @drjosflynn
RT @BAPNnephrology: Timezones below #nephjc #PREDNOS @ADC_BMJ @ArchivesEandP @RCPCHtweets https://t.co/LpLfO51F8B
Andrew Bomback @asbomback
RT @hswapnil: Finally! Getting ready for upcoming #NephJC book club (July 23/24) https://t.co/JZYJYGsP0p
Sara Jdiaa @JdiaaSara
Membraneous spikes
Nephrology Jrnl Club @NephJC
#NephJC this week: the PREDNOS trial from @bmj_latest - https://t.co/5ezDflGBLt
Nathaniel Reisinger, MD, FASN @nephrothaniel
RT @NephJC: #NephJC this week: the PREDNOS trial from @bmj_latest - https://t.co/5ezDflGBLt
Ayanfe Obilana @AyanfeObilana
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Sally Johnson @docsallyj
RT @BAPNnephrology: Timezones below #nephjc #PREDNOS @ADC_BMJ @ArchivesEandP @RCPCHtweets https://t.co/LpLfO51F8B
Justin Davis @jbda19
RT @NephJC: #NephJC this week: the PREDNOS trial from @bmj_latest - https://t.co/5ezDflGBLt
Eric Au @ericau
RT @NephJC: #NephJC this week: the PREDNOS trial from @bmj_latest - https://t.co/5ezDflGBLt
Swapnil Hiremath, MD, MPH @hswapnil
@mudgey2 @toates_19 wasn’t impressed when we discussed on #nephjc https://t.co/VPhnDryzRa
Sri Lekha Tummalapalli, MD, MBA @LTummalapalli
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Nephrology Jrnl Club @NephJC
T-1 hour to #NephJC chat tonight at 9 pm Eastern Time on the PREDNOS trial published @bmj_latest https://t.co/lwxyN4uUdE Our summary here https://t.co/WkqkPNKE3i Commentary by @KidneyCathy https://t.co/91i92GiSsN & VA by @jbda19 https://t.co/wpHcEULFfD
Cathy Quinlan @KidneyCathy
RT @NephJC: T-1 hour to #NephJC chat tonight at 9 pm Eastern Time on the PREDNOS trial published @bmj_latest https://t.co/lwxyN4uUdE Our s…
Justin Davis @jbda19
RT @NephJC: T-1 hour to #NephJC chat tonight at 9 pm Eastern Time on the PREDNOS trial published @bmj_latest https://t.co/lwxyN4uUdE Our s…
Eric Au @ericau
RT @NephJC: T-1 hour to #NephJC chat tonight at 9 pm Eastern Time on the PREDNOS trial published @bmj_latest https://t.co/lwxyN4uUdE Our s…
Susan Thomas @kidsbeansdoc
RT @NephJC: T-1 hour to #NephJC chat tonight at 9 pm Eastern Time on the PREDNOS trial published @bmj_latest https://t.co/lwxyN4uUdE Our s…
Nephrology Jrnl Club @NephJC
#NephJC chat tonight on PREDNOS Trial @bmj_latest https://t.co/lwxyN4uUdE Join us in 10 minutes!
Katalin Susztak @KSusztak
RT @junghoon_sonMD: CKD stage transition #dataviz over 1 year. Fancy algorithms may be nice but systematic monitoring of chronic conditions…
Justin Davis @jbda19
RT @NephJC: #NephJC chat tonight on PREDNOS Trial @bmj_latest https://t.co/lwxyN4uUdE Join us in 10 minutes!
Katie Jones @Kat1eJones
RT @NephJC: #NephJC this week: the PREDNOS trial from @bmj_latest - https://t.co/5ezDflGBLt
Mario Funes MD @MarioFunesMD
RT @NephJC: #NephJC chat tonight on PREDNOS Trial @bmj_latest https://t.co/lwxyN4uUdE Join us in 10 minutes!
Nephrology Jrnl Club @NephJC
Hello and welcome to our discussion tonight on the PREDNOS trial published online at @bmj_latest on steroids in childhood nephrotic syndrome https://t.co/lwxyN4uUdE @profnickwebb #NephJC
Ajaya @Renaltubules
Ajaya. Nepal. 6.45am. coi: loves Peds Nephro. on trek to Namchebazar @kidney_boy #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: Hello and welcome to our discussion tonight on the PREDNOS trial published online at @bmj_latest on steroids in childhood nephr…
Nephrology Jrnl Club @NephJC
I am Eric Au @ericau, a nephrologist from Sydney, Australia, #NSMC intern and your host today. No COI. Welcome! #NephJC
Nephrology Jrnl Club @NephJC
@Renaltubules @kidney_boy Welcome! #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
Swapnil Hiremath #nephjc cofounder From @OttawaHospital Not a paediatric nephrologist No other CoI https://t.co/qNHmUpp8II
Nephrology Jrnl Club @NephJC
Please introduce yourself (even if you’re lurking) and declare any COIs. Don’t forget the hashtag #NephJC
Nephrology Jrnl Club @NephJC
@hswapnil @OttawaHospital Hi @hswapnil ! #NephJC
Brian Stotter, MD @StotterMD
Brian Stotter, nephrology fellow (for 3 more days!) at @BostonChildrens. No COI #nephJC
Nephrology Jrnl Club @NephJC
@StotterMD @BostonChildrens Hi @StotterMD ! #NephJC
Nephrology Jrnl Club @NephJC
Anyone new to #NephJC is always more than welcome. Here’s a quick guide on ‘How to NephJC.’ #NephJC https://t.co/4ig7lGXsEo
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Edgar Lerma, Chicago-based Nephrologist #NephJC Photo Credit: Barry Butler Photography 📸 https://t.co/eWMVI6KFon https://t.co/y6UUXOzE2G
Kathy Lee-Son @KLS_leeson
#NephJC Kathy Lee-Son @KLS_leeson Peds Nephrologist from @uiowa no COI, and want to hear about this RCT!
Tiffany Caza @Tiff_Caza
The PREDNOS trial on #nephjc. . . happening now! 😊. Check out this great summary for starters.
Katie Jones @Kat1eJones
Hi! I’m Katie. Soon to be 2nd year Ped neph fellow at Johns Hopkins. First #nephJC ! Plan to mostly lurk.
Nephrology Jrnl Club @NephJC
Routine housekeeping out of the way first: We recommend you use the native client in browser https://t.co/LkGCHacSvg or Tweetdeck. Tchat will truncate tweets at 140 #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
Chia-shi Wang, pediatric nephrologist at Emory University in Atlanta, GA. no COI. #NephJC
Abhilash Koratala @KoraAbhi
Hi, Abhi aka @NephroP No COI Participant with low reflection but high absorption ☝🏽#NephJC
Krithika Mohan @krithicism
Krithika Mohan, nephrology fellow , India, no COI, will be lurking mostly #NephJC
Mario Funes MD @MarioFunesMD
Mario Funes. PGY2 Internal Medicine in New Brunswick, NJ. #NSMC intern 2019. Countdown for nephrology match has started. No COI. #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: Anyone new to #NephJC is always more than welcome. Here’s a quick guide on ‘How to NephJC.’ #NephJC https://t.co/4ig7lGXsEo
Nephrology Jrnl Club @NephJC
Hi @CWPedNephMD @Kat1eJones @edgarvlermamd @KLS_leeson! Thanks for joining #nephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: Routine housekeeping out of the way first: We recommend you use the native client in browser https://t.co/LkGCHacSvg or Tweetde…
Nephrology Jrnl Club @NephJC
If you’re not familiar with them already, check out the amazing guide to the values of our #NephJC community put together by @Nephro_Sparks and @SLeonMD https://t.co/b3Y4ALpGit https://t.co/qwr5awziHM
Hector Madariaga @HecmagsMD
Héctor Madariaga. Cambridge, MA. No COI. Lurking tonight #NephJC
Stella Shin @BabyBeanDoc
Stella Shin. Pediatric nephrologist at Emory in Atlanta. No COI. #NephJC
Nephrology Jrnl Club @NephJC
@krithicism Hi @krithicism ! #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: If you’re not familiar with them already, check out the amazing guide to the values of our #NephJC community put together by @N
Cathy Quinlan @KidneyCathy
Cathy Quinlan. No COI. Paed neph. Following in clinic so will be quiet. #nephJC
Alyssa Riley @PediNephMD
Alyssa Riley, peds neph, Austin Tx, no coi #NephJC
Tiffany Caza @Tiff_Caza
@NephJC Hi!! I'm Tiff Caza. I'm a kidney path fellow and NSMC intern (pod ⚡). No COI. Looking forward to learning about the PREDNOS trial! #nephJC
Nephrology Jrnl Club @NephJC
Tonight we are discussing the ‘Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation’ https://t.co/lwxyN4uUdE @bmj_latest @profnickwebb #NephJC
Nephrology Jrnl Club @NephJC
@BabyBeanDoc Welcome! #nephJC
Nephrology Jrnl Club @NephJC
@PediNephMD Welcome! #NephJC
Louisa Butler @Kidney_Louisa
Hi! I'm Louisa - Nephrology Fellow at RCH Melbourne. No COI. Just lurking today - here to learn! #nephjc
Nephrology Jrnl Club @NephJC
RT @NephJC: Tonight we are discussing the ‘Long term tapering versus standard prednisolone treatment for first episode of childhood nephrot…
Nephrology Jrnl Club @NephJC
Check out the #NephJC summary of the article at https://t.co/WkqkPO2frS & commentary by @KidneyCathy at https://t.co/91i92G1hBf
Mario Funes MD @MarioFunesMD
RT @NephJC: Check out the #NephJC summary of the article at https://t.co/WkqkPO2frS & commentary by @KidneyCathy at https://t.co/91i92G1hBf
Larissa Krüger @nephron_andon
Larissa - transitioning from Connecticut to Boston, fellow to be in a couple of days! Let’s learn! #nephJC
Nephrology Jrnl Club @NephJC
And the fabulous #VisualAbstract from @jbda19 #NephJC https://t.co/OmNjqLVpsI
Edgar V. Lerma 🇵🇭 @edgarvlermamd
PREDNOS: Length of steroids for pediatric nephrotic syndrome ca. 2019 #VisualAbstract by @jbda19 #NephJC #Nephpearls 👉🏼 https://t.co/wn81b8bWxn https://t.co/zSGR9MLQ0Y
Krithika Mohan @krithicism
RT @NephJC: And the fabulous #VisualAbstract from @jbda19 #NephJC https://t.co/OmNjqLVpsI
Nephrology Jrnl Club @NephJC
RT @NephJC: Check out the #NephJC summary of the article at https://t.co/WkqkPO2frS & commentary by @KidneyCathy at https://t.co/91i92G1hBf
Nephrology Jrnl Club @NephJC
Abbreviations for the chat: NS: Nephrotic Syndrome FRNS: Frequently relapsing nephrotic syndrome SRNS: Steroid resistant nephrotic syndrome #NephJC
Tiffany Caza @Tiff_Caza
RT @NephJC: And the fabulous #VisualAbstract from @jbda19 #NephJC https://t.co/OmNjqLVpsI
Emily Steinbach @SteinbachEmily
#NephJC Emily Steinbach @SteinbachEmily from @uiowa! Future physician scientist and Peds Nephrologist. No COI. Just lurking and learning!
Michelle Rheault @rheault_m
@nephjc Michelle’s here! Just touched down in DC for the @Nephcure meeting. I’m a pediatrician. I can’t afford airplane WiFi #NephJC https://t.co/560tv2vKd0
Nephrology Jrnl Club @NephJC
Moving on to T0 and the background. #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8bWxn https://t.co/C8xhAb16Y5
Madeleine Didsbury @KidneyMad
#nephJC Maddy, renal resident at RCH Melbourne. No COI. Keen to learn more about nephrotic syndrome.
Scherly Leon, MD @SLeonMD
Scherly Leon nephrologist in NYC. No COI. #NephJC I can't even lurk just saying hello to all. Have a great chat.
Brian Stotter, MD @StotterMD
@edgarvlermamd @CJASN Could be a novel #NephJC
Nephrology Jrnl Club @NephJC
T0A: Childhood nephrotic syndrome is the most common form of glomerular disease in children. Is this a condition you see commonly in your practice? #NephJC
Nephrology Jrnl Club @NephJC
T0B: The 2012 @goKDIGO guidelines for #GN here: https://t.co/lp83YKUEdH How do you treat childhood NS? #NephJC
Justin Davis @jbda19
@NephJC Justin #NSMC intern. Currently in transplant clinic but will be back to host the European chat tomorrow (at a very strange Aussie Timezone. Good old down under!) #nephjc
Brian Stotter, MD @StotterMD
@NephJC All day, every day #nephJC
Michelle Rheault @rheault_m
@StotterMD @BostonChildrens Ha! Pretty soon you have to decide NS steroid course on your own. It’s terrifying. #NephJC
Ajaya @Renaltubules
Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common in people of South Asian origin -90% are SSNS -80% will Relapse, of these relapse 50% are FRNS or SDNS -No known ideal steroid dose or duration #NephJC
Simon Carter @sc_kidney
Simon Carter- Paed Neph, first time on NephJC - excited discussing Prednos! No COI. #NephJC
Nephrology Jrnl Club @NephJC
RT @Renaltubules: Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common…
John David Spencer @kidneytweets
JD Spencer - peds neph Columbus OH #nephjc
Abhilash Koratala @KoraAbhi
RT @Renaltubules: Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common…
Nephrology Jrnl Club @NephJC
@goKDIGO recommends treating childhood nephrotic syndrome with steroids for at least 12 weeks, starting with oral pred at 60 mg/m2 daily for 4-6 weeks, then alt day oral pred at 40 mg/m2 for 2-5 months. #NephJC
Arinarami @nephrologyunit
RT @NephJC: Hello and welcome to our discussion tonight on the PREDNOS trial published online at @bmj_latest on steroids in childhood nephr…
Chia-shi Wang, MD, MSc @CWPedNephMD
One of the most common diseases we treat in pediatric nephrology. FRNS/SDNS rates are what we see in the U.S. as well #nephjc
Nephrology Jrnl Club @NephJC
RT @CWPedNephMD: One of the most common diseases we treat in pediatric nephrology. FRNS/SDNS rates are what we see in the U.S. as well #nep
Nephrology Jrnl Club @NephJC
T0C: As children with nephrotic syndrome often relapse after initial therapy, several studies have looked at whether the duration and dose of steroid treatment affects the risk of relapse #nephJC
Ng Jia Hwei @jiahweing
@NephJC Jia here, NSMC intern. No COI. #nephjc
Timothy Yau @Maximal_Change
Tim Yau from @WUNephrology lurking tonight #NephJC
Nephrology Jrnl Club @NephJC
T0D: A @CochraneKidney review updated in 2015 found that a longer course of steroid therapy reduced the risk of relapse and frequently relapsing nephrotic syndrome (FRNS) but this was mainly in older studies with high bias https://t.co/Uw12JCfC9L #NephJC
Joseph Flynn @drjosflynn
Joseph Flynn, ped nephrologist. No COI that I can think of. On my commute home so may not be able to contribute much #nephjc
Levin 👨‍🔬 @codezero123456
RT @edgarvlermamd: Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8…
Joseph Flynn @drjosflynn
RT @NephJC: Anyone new to #NephJC is always more than welcome. Here’s a quick guide on ‘How to NephJC.’ #NephJC https://t.co/4ig7lGXsEo
Brian Stotter, MD @StotterMD
@drjosflynn Welcome! #nephJC
Brian Stotter, MD @StotterMD
@Maximal_Change @WUNephrology Hey Tim! #nephJC
Tulun Sokit 🇲🇾 @tulunsokit
For Paediatricians and Paeds Nephros
Nephrology Jrnl Club @NephJC
T0E: Some more recent studies have also shown no benefit with a longer course of steroid therapy compared to a shorter duration of steroid course https://t.co/MFTw8UGzy3 https://t.co/N7vlfKmpC0 #nephJC
Nephrology Jrnl Club @NephJC
Take a look at @rheault_m’s tweets on pediatric NS trials and variability in treatment approach #NephJC https://t.co/97bpc44gdX
Ng Jia Hwei @jiahweing
RT @NephJC: And the fabulous #VisualAbstract from @jbda19 #NephJC https://t.co/OmNjqLVpsI
Nephrology Jrnl Club @NephJC
T0F: What dose & duration of steroid therapy do you use to treat childhood nephrotic syndrome? #NephJC
Ajaya @Renaltubules
Prolonging duration of steroid in first episode of Nephrotic syndrome will dealy the first relapse but NOT rate of FRNS or SDNS #nephjc
Nephrology Jrnl Club @NephJC
RT @NephJC: T0B: The 2012 @goKDIGO guidelines for #GN here: https://t.co/lp83YKUEdH How do you treat childhood NS? #NephJC
Michelle Rheault @rheault_m
@NephJC This is the most important outcome, in my opinion. If one steroid regimen at first can prevent a frns/sdns course, then I would use it. #NephJC
Tiffany Caza @Tiff_Caza
RT @Renaltubules: Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common…
Jennie Lin, MD MTR @jenniejlin
Hola from layover purgatory at LAX. Just lurking until boarding time. No COI #nephJC
Nephrology Jrnl Club @NephJC
Moving on to T1 Methods shortly. #NephJC
Nephrology Jrnl Club @NephJC
RT @rheault_m: @NephJC This is the most important outcome, in my opinion. If one steroid regimen at first can prevent a frns/sdns course, t…
Nephrology Jrnl Club @NephJC
Thanks for the input. Let’s go to T1 to discuss the methods. #NephJC
Katie Jones @Kat1eJones
RT @NephJC: T0D: A @CochraneKidney review updated in 2015 found that a longer course of steroid therapy reduced the risk of relapse and fre…
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T0C: As children with nephrotic syndrome often relapse after initial therapy, several studies have looked at whether the durati…
Nephrology Jrnl Club @NephJC
T1A: This was a multicenter, double-blinded RCT conducted involving 125 general hospitals and tertiary pediatric centers in the UK #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: Take a look at @rheault_m’s tweets on pediatric NS trials and variability in treatment approach #NephJC https://t.co/97bpc44gdX
Joel Topf, MD FACP @kidney_boy
Sorry I'm late. Doing Tech Support for my parents. Joel Topf, community nephrologist. Detroit Michigan. #nephJC
Nephrology Jrnl Club @NephJC
RT @NephJC: T1A: This was a multicenter, double-blinded RCT conducted involving 125 general hospitals and tertiary pediatric centers in the…
Michelle Starr @mcstarr1
Sorry for the late join - flat tire! Michelle Starr, pediatric nephrology fellow in Seattle. No coi. #nephjc
Nephrology Jrnl Club @NephJC
T1B: Children aged 1-14 years with a first episode of idiopathic nephrotic syndrome without previous treatment were included #NephJC
Aisha Shaikh @aishaikh
This is Aisha from NYC. No COI #nephJC
Joel Topf, MD FACP @kidney_boy
@NephJC @Renaltubules Love me some Namche Bazaar. Wash push to name our new puppy Tenzing. #NephJC
Nephrology Jrnl Club @NephJC
T1C: Potential participants received initial treatment with 60 mg/m2 of prednisolone daily for 4 weeks. Those who appeared steroid sensitive (3 days with zero/trace proteinuria on urine dipstick) were recruited and randomized to extended or standard course treatment #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Investigations of glucocorticoid action in glomerulonephritis ca. 2017 from @JASN_News #Nephpearls #NephJC 👉🏼 https://t.co/QciSe5MXJ6 https://t.co/Mk0PtWZl2R
Sami Alasfar @SamiAlasfar
Sami Alasfar, transplant nephroloist, Baltimore #nephJC
Michelle Rheault @rheault_m
@NephJC I can not overstate how difficult it must have been for @profnickwebb to get all of those centers to agree to a regimen. #nephjc https://t.co/zZhPFpSAOE
Nephrology Jrnl Club @NephJC
T1D: Standard course: 4 more weeks of prednisolone 40 mg/m2 on alternate days (total 8 weeks) + placebo for 8 weeks Extended course: 12 more weeks of prednisolone starting 60 mg/m2 and tapering by 10 mg/m2 every 2 weeks (total 16 weeks) #NephJC https://t.co/8c79nQmkq1
Swapnil Hiremath, MD, MPH @hswapnil
RT @rheault_m: @NephJC I can not overstate how difficult it must have been for @profnickwebb to get all of those centers to agree to a regi…
Ajaya @Renaltubules
This trial is well design - Trail carried in most centre of UK - Trail included 1/3 of Nephrotic population of UK - High enrollement rate - International Nephrotic classification used - previous flaws in RCT were rectified. well designed trail #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T1D: Standard course: 4 more weeks of prednisolone 40 mg/m2 on alternate days (total 8 weeks) + placebo for 8 weeks Extended…
Nephrology Jrnl Club @NephJC
@rheault_m @profnickwebb Impressive number of hospitals involved in the trial! #NephJC
Nephrology Jrnl Club @NephJC
T1E: What do you think about the recruitment and the two different intervention arms? #NephJC
Joel Topf, MD FACP @kidney_boy
@rheault_m @NephJC @Nephcure Let's start a @GoFundMe for Michelle's airborne Wifi #NephJC
Nephrology Jrnl Club @NephJC
RT @Renaltubules: This trial is well design - Trail carried in most centre of UK - Trail included 1/3 of Nephrotic population of UK - High…
Sami Alasfar @SamiAlasfar
RT @Renaltubules: This trial is well design - Trail carried in most centre of UK - Trail included 1/3 of Nephrotic population of UK - High…
Swapnil Hiremath, MD, MPH @hswapnil
@rheault_m @NephJC @profnickwebb And the patients & parents (all checking albuminuria!) #nephjc
Chia-shi Wang, MD, MSc @CWPedNephMD
Incredible and amazing collaboration. One question is the exclusion of those with known nonadherence. How is this determined? How many potential patients were not included? #nephjc
Nephrology Jrnl Club @NephJC
T1F: Participants were assessed at regular visits for at least 24 months, up to 48 months. Primary outcome was time from starting open label prednisolone treatment to first relapse #NephJC
Nephrology Jrnl Club @NephJC
T1F: Secondary outcomes incl subgroup analyses by age & ethnicity; relapse rate, incidence of FRNS & steroid dependent NS, use of other immunosuppression & adverse events. Parents also completed behavior + QoL surveys Height, weight, BMI + BP were exploratory outcomes. #NephJC
Michelle Rheault @rheault_m
@NephJC I think of 12 week course as “standard”. (My bias) I would have liked to see that as an arm. #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @CWPedNephMD: Incredible and amazing collaboration. One question is the exclusion of those with known nonadherence. How is this determin…
Nephrology Jrnl Club @NephJC
T1G: What do you think of the outcomes of this trial? Did the trial include all important clinical and patient outcomes? #NephJC
Michelle Starr @mcstarr1
@rheault_m @NephJC I agree! Considering that this seems to be what most programs and pediatric nephrologists consider their “usual” treatment course #nephjc
Nephrology Jrnl Club @NephJC
@CWPedNephMD Not sure if they explained the adherence criteria. But of those included in the trial "13% (n=29) reported missed doses and most of these patients reported missing only one or two doses." #NephJC
Brian Stotter, MD @StotterMD
Thought it was interesting that they randomized children only after showing steroid sensitivity in 2-3 weeks of full-dose. 1/2 #nephJC
Katie Jones @Kat1eJones
@hswapnil @rheault_m @NephJC @profnickwebb The strength of the parents of kidney patients and their willingness to participate in trials never fails to amaze me! #nephJC
Michelle Rheault @rheault_m
@hswapnil @NephJC @profnickwebb Asking parents to check urine protein is standard practice in peds. Very useful. #nephjc
Nephrology Jrnl Club @NephJC
Moving on to T2 to discuss the results soon #NephJC
Nephrology Jrnl Club @NephJC
@mcstarr1 @rheault_m Would you then want to compare the 12 week with an even longer "extended" course? #nephJC
Nephrology Jrnl Club @NephJC
RT @NephJC: T1G: What do you think of the outcomes of this trial? Did the trial include all important clinical and patient outcomes? #Neph
Brian Stotter, MD @StotterMD
20% of children with SSNS may respond after 4 weeks of full-dose. #NephJC
Samaya @TarSamMD
Samaya from Houston late arrival sorry #NSMC #NephJC
Charlie Hall @CharlesHallMD
A little late to the party. Charlie here, London medical trainee. #NSMCIntern Working nights, thus mainly lurking. No COI. #nephJC
Michelle Rheault @rheault_m
@CWPedNephMD Agree. No adherence is hard to sort out during a first episode. Later, sure, I can tell you who’s not taking meds ... #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
@StotterMD That seems like a strength? What’s the point of enrolling steroid resistant NS? #nephjc
Nephrology Jrnl Club @NephJC
RT @StotterMD: Thought it was interesting that they randomized children only after showing steroid sensitivity in 2-3 weeks of full-dose. 1…
Joel Topf, MD FACP @kidney_boy
@hswapnil @rheault_m @NephJC @profnickwebb How do you dip sticks with a diaper? #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
We know from survey studies that adherence is closer to just 50%. Urine monitoring adherence is also around 50%. The excellent reported adherence in this trial is amazing. Which suggest to me the included patients do not fully represent "real life". #nephjc
Dr. Deidra Crews @DrDeidraCrews
#NephJC Good evening! I am an adult nephrologist @hopkinsneph No COI
Nephrology Jrnl Club @NephJC
T2A: A total of 237 children with randomized (119 extended + 118 standard course). Authors said this was 1/3 of all UK children with childhood nephrotic syndrome during the study period! #NephJC
Nephrology Jrnl Club @NephJC
RT @CWPedNephMD: Incredible and amazing collaboration. One question is the exclusion of those with known nonadherence. How is this determin…
Swapnil Hiremath, MD, MPH @hswapnil
Whoah Differing standards #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
RT @StotterMD: 20% of children with SSNS may respond after 4 weeks of full-dose. #NephJC
Brian Stotter, MD @StotterMD
@hswapnil Children who take longer to respond, but are still steroid-sensitive are at higher risk for relapse. #NephJC
Ajaya @Renaltubules
@kidneytweets @rheault_m @NephJC Is this ethical to placebo arm? #nephjc
Nephrology Jrnl Club @NephJC
T2A cont: 14 patients withdrew from the study due steroid resistance and were excluded from analysis. A small number in each arm discontinued due to inability to take trial drug, withdrew consent or were lost to follow-up #NephJC https://t.co/RdqOoNUqZb
Cathy Quinlan @KidneyCathy
@hswapnil Likewise we have a 12 week course @RCHMelbourne #nephjc
Sarah Gleeson @sarah_gleeson_
Sarah here, renal reg. Working nights so lurking ++ . No COI. #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
@StotterMD Got it! Good point #nephjc
Michelle Rheault @rheault_m
@NephJC @mcstarr1 No. Would want to go shorter steroid course than even 8 week (or non-steroid). The original ISKDC regimen we still go by was plucked out of the air. #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T2A cont: 14 patients withdrew from the study due steroid resistance and were excluded from analysis. A small number in each…
Brian Stotter, MD @StotterMD
@hswapnil Not sure how universal it is, but where I train we don’t call a child steroid resistant/start planning biopsy until they have shown no response by 8 weeks #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @StotterMD: @hswapnil Not sure how universal it is, but where I train we don’t call a child steroid resistant/start planning biopsy unti…
Swapnil Hiremath, MD, MPH @hswapnil
RT @rheault_m: @NephJC @mcstarr1 No. Would want to go shorter steroid course than even 8 week (or non-steroid). The original ISKDC regimen…
Cathy Quinlan @KidneyCathy
@hswapnil @RCHMelbourne And will you change @rheault_m ?#nephjc
Nephrology Jrnl Club @NephJC
RT @rheault_m: @NephJC @mcstarr1 No. Would want to go shorter steroid course than even 8 week (or non-steroid). The original ISKDC regimen…
Joseph Flynn @drjosflynn
Right. 6wks daily/6wks QODis pretty much standard IMHO #NephJC
Ajaya @Renaltubules
@StotterMD @hswapnil also had a high risk for late steroid resistance #nephjc
Nephrology Jrnl Club @NephJC
T2B: Baseline characteristics were similar between the two groups as expected for an RCT. Mean age 4.9 years, Girls 35%. 20% of participants were of South Asian ethnicity. Is this similar to the patients you see with childhood nephrotic syndrome? #NephJC https://t.co/M3KQ00lqDO
Brian Stotter, MD @StotterMD
@Renaltubules @hswapnil https://t.co/OgqN0c1uTK #NephJC
Nephrology Jrnl Club @NephJC
RT @CWPedNephMD: We know from survey studies that adherence is closer to just 50%. Urine monitoring adherence is also around 50%. The excel…
Joseph Flynn @drjosflynn
@NephJC @mcstarr1 @rheault_m That's been done, w/a prolonged taper. No benefit. #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
@drjosflynn Welcome back - Don’t drive & tweet Jos! #NephJC
Nephrology Jrnl Club @NephJC
T2C: For primary outcome, there was no difference in time to first relapse between the extended (16 week) course of prednisolone treatment vs a standard (8 week) course (p = 0.28, HR 0.87, 95% CI 0.65-1.17) What do you think of this result? #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T2B: Baseline characteristics were similar between the two groups as expected for an RCT. Mean age 4.9 years, Girls 35%. 20% o…
Joel Topf, MD FACP @kidney_boy
@NephJC I don't understand, didn't they need to be proteinuria to be enrolled? Doesn't that mean they were all steroid sensitive at randomization? #NephJC
Michelle Rheault @rheault_m
@kidneytweets @NephJC We did that experiment in the 39’s and 40’s. 70% of kids died of infection. Placebo arm not ethical in my opinion. #NephJC.
Nephrology Jrnl Club @NephJC
#NephJC
Mohsin Aijaz @AligMohsin
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Brian Stotter, MD @StotterMD
@kidney_boy @NephJC They were randomized once they were proven to be in remission after starting full 60 mg/m2 dosing #NephJC
Michelle Rheault @rheault_m
@KidneyCathy @hswapnil @RCHMelbourne Sigh, probably not. #NephJC
Joel Topf, MD FACP @kidney_boy
@StotterMD @NephJC so how could they be steroid resistant? #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @rheault_m: @kidneytweets @NephJC We did that experiment in the 39’s and 40’s. 70% of kids died of infection. Placebo arm not ethical in…
Nephrology Jrnl Club @NephJC
@kidney_boy Think a small number appeared steroid sensitive then later became resistant? #nephJC
Nephrology Jrnl Club @NephJC
T2D: For secondary outcomes, there were no differences in the mean number of relapses or the proportion developing frequently relapsing or steroid dependent nephrotic syndrome or requiring 2nd line immunosuppressive treatment. #NephJC https://t.co/PoBRRtVrpa
Ajaya @Renaltubules
When do you call Steroid resistant Nephrotic syndrome? - ours 4 week #nephjc
Chia-shi Wang, MD, MSc @CWPedNephMD
@NephJC @kidney_boy this seemed what happened. #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
@NephJC Glass half full or half empty? #NephJC https://t.co/noCtg2vuCE
Nephrology Jrnl Club @NephJC
@rheault_m @KidneyCathy @hswapnil @RCHMelbourne Why not? #nephJC
Brian Stotter, MD @StotterMD
@Renaltubules Wow that’s tight. We say 8 weeks. #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T2D: For secondary outcomes, there were no differences in the mean number of relapses or the proportion developing frequently r…
Cathy Quinlan @KidneyCathy
@rheault_m @hswapnil @RCHMelbourne Is that a sigh because it’s just so hard to get consensus in such an opinion based field? If so, I hear ya #nephjc
Nephrology Jrnl Club @NephJC
T2E: The extended course treatment did not lead to more steroid related side effects or serious adverse events. Interestingly, poor behavior was reported more often by parents in the standard course group, but this was not seen in the Achenbach child behavior checklist #NephJC https://t.co/mN7KUCF9Zj
Brian Stotter, MD @StotterMD
@Renaltubules Old ISKDC studies show 80% of minimal change respond by 4 weeks, still 20% to wait on #NephJC
Ajaya @Renaltubules
@CWPedNephMD @NephJC @kidney_boy but if there became resistant after 4 week of treatment .they were excluded #nephjc
Joseph Flynn @drjosflynn
@Renaltubules 6 wks no response. But begin to worry at 4wks.#NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T2E: The extended course treatment did not lead to more steroid related side effects or serious adverse events. Interestingly,…
Ng Jia Hwei @jiahweing
RT @Renaltubules: Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common…
Swapnil Hiremath, MD, MPH @hswapnil
@NephJC This is so important More steroids were not harmful! #NephJC
Joseph Flynn @drjosflynn
@NephJC No surprise there really. #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
@NephJC The primary outcome was a bit surprising given the median time to first relapse was 139 days. Which is after the 16 week window. So I expected those with 8 weeks of treatment to relapse a bit sooner #nephjc
Nephrology Jrnl Club @NephJC
T2F: The investigators also did a cost effectiveness analysis (suppl appendix) & found extended treatment was cost effective - fewer primary care & hospital visits, lower cost of some drugs + better QoL at some time points. Could this be a benefit of extended treatment? #NephJC https://t.co/TQjpf2iA5F
Swapnil Hiremath, MD, MPH @hswapnil
As @KidneyCathy pointed out - main result also is that 80% had a relapse Eventually #nephjc https://t.co/Vkw8NRFDmg
Brian Stotter, MD @StotterMD
@hswapnil @NephJC Linear growth appears to be missing (or I’m missing it) #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @StotterMD: @hswapnil @NephJC Linear growth appears to be missing (or I’m missing it) #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
@CWPedNephMD @NephJC Could it be since they pushed all relapses to 18 weeks? #NephJC
Nephrology Jrnl Club @NephJC
Extended course was cheaper - and more effective; see image #NephJC https://t.co/JqHGc6XFr8
Chia-shi Wang, MD, MSc @CWPedNephMD
What is really confusing is Fig 1. They show 50 discontinued drug during d/t relapse after 4 weeks in Standard and 29 discontinued d/t relapse in extended. It seemed there was a difference in the relapse rate just in Fig1. #nephjc
Nephrology Jrnl Club @NephJC
@StotterMD @hswapnil Height/weight/BMI were exploratory outcomes "The mean height, weight, and body mass index z scores did not differ between the two treatment groups at any time point throughout the trial period." #NephJC
Nephrology Jrnl Club @NephJC
RT @hswapnil: As @KidneyCathy pointed out - main result also is that 80% had a relapse Eventually #nephjc https://t.co/Vkw8NRFDmg
Chia-shi Wang, MD, MSc @CWPedNephMD
@hswapnil @NephJC I thought so but the sensitivity analysis also showed no difference. #NephJC
Nephrology Jrnl Club @NephJC
#nephJC https://t.co/cazsUAM3JS
Michelle Rheault @rheault_m
@kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resistant over time. High risk for post transplant recurrence. #NephJC https://t.co/JP9g8jOhap
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: @StotterMD @hswapnil Height/weight/BMI were exploratory outcomes "The mean height, weight, and body mass index z scores did no…
Nephrology Jrnl Club @NephJC
T2G: Anything more you would like to know about the results? #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @rheault_m: @kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resis…
Michelle Starr @mcstarr1
@CWPedNephMD I agree - this really confused me! #nephjc
Nephrology Jrnl Club @NephJC
Thanks to everyone for the great discussion. Heading to T3 and conclusions soon. #NephJC
Cathy Quinlan @KidneyCathy
@hswapnil @NephJC Yes - perhaps we've swung towards too much steroid fear.... At the small alternate day doses it may be worth de-escalation of anxiety #nephjc
Nephrology Jrnl Club @NephJC
RT @rheault_m: @kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resis…
Nephrology Jrnl Club @NephJC
#nephJC
Swapnil Hiremath, MD, MPH @hswapnil
RT @KidneyCathy: @hswapnil @NephJC Yes - perhaps we've swung towards too much steroid fear.... At the small alternate day doses it may be w…
Tiffany Caza @Tiff_Caza
RT @rheault_m: @kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resis…
Nephrology Jrnl Club @NephJC
RT @NephJC: T2F: The investigators also did a cost effectiveness analysis (suppl appendix) & found extended treatment was cost effective -…
Nephrology Jrnl Club @NephJC
T3A: The authors concluded that an extended 16 week course of prednisolone did not reduce the rate of relapse compared to a standard 8 week course. Extended course steroid treatment did not lead to more adverse events. #NephJC
Joseph Flynn @drjosflynn
@hswapnil @KidneyCathy Typical for childhood NS. Almost never see (OR hear of) kids who have had just one episode. #NephJC
Cathy Quinlan @KidneyCathy
@hswapnil @rheault_m @NephJC @profnickwebb That's standard - parents describe the dipstick as "the most stressful 60 seconds of their day". They wait to see the colour change before planning how their day will go. #nephjc
Nephrology Jrnl Club @NephJC
#nephJC
Brian Stotter, MD @StotterMD
@drjosflynn @hswapnil @KidneyCathy I always discuss with families upfront that NS is a relapsing disease. Single episodes are rare. #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
@NephJC Absolutely, always makes it just a bit more difficult to extend to clinical practice.#nephjc
Cathy Quinlan @KidneyCathy
RT @NephJC: T3A: The authors concluded that an extended 16 week course of prednisolone did not reduce the rate of relapse compared to a sta…
Nephrology Jrnl Club @NephJC
9:47 T3B: What are your thoughts on the results? Standard course is good enough? Extended course is just as safe? Will this change how you treat children presenting with nephrotic syndrome? #NephJC
Nephrology Jrnl Club @NephJC
#nephJC
Cathy Quinlan @KidneyCathy
RT @rheault_m: @kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resis…
Nephrology Jrnl Club @NephJC
RT @NephJC: 9:47 T3B: What are your thoughts on the results? Standard course is good enough? Extended course is just as safe? Will this c…
Joseph Flynn @drjosflynn
RT @StotterMD: @drjosflynn @hswapnil @KidneyCathy I always discuss with families upfront that NS is a relapsing disease. Single episodes ar…
Nephrology Jrnl Club @NephJC
RT @NephJC: T3A: The authors concluded that an extended 16 week course of prednisolone did not reduce the rate of relapse compared to a sta…
Nephrology Jrnl Club @NephJC
T3C: Any limitations of the study? What are areas for future research on the treatment of childhood nephrotic syndrome? #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
@NephJC For now, sticking with standard course since there's no compelling reason to extend treatment.#NephJC
Jinn-Yuh Guh @guhjy
RT @edgarvlermamd: Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8…
Nephrology Jrnl Club @NephJC
Last 10 minutes: What’s your take home message? #NephJC
Nephrology Jrnl Club @NephJC
RT @NephJC: Last 10 minutes: What’s your take home message? #NephJC
Joseph Flynn @drjosflynn
@NephJC Won't affect my practice b/c they did not test the regimen that most ppl seem to use - based on poll by @rheault_m. #NephJC
Nephrology Jrnl Club @NephJC
@drjosflynn @rheault_m Which regimens would you ideally like to see tested/compared? #NephJC
Cathy Quinlan @KidneyCathy
@NephJC 80% of kids relapse. This should influence how we counsel parents. #nephjc
Michelle Rheault @rheault_m
@drjosflynn @NephJC As we all know, Twitter polls are binding. #NephJC https://t.co/XLuNXdEuaX
Edgar V. Lerma 🇵🇭 @edgarvlermamd
MT @NephJC @ericau PREDNOS: The authors concluded that an extended 16 week course of prednisolone did not reduce the rate of relapse compared to a standard 8 week course 📌 Extended course steroid treatment did not lead to more adverse events. #NephJC #Nephpearls
Nephrology Jrnl Club @NephJC
#NephJC
Nephrology Jrnl Club @NephJC
RT @KidneyCathy: @NephJC 80% of kids relapse. This should influence how we counsel parents. #nephjc
Tiffany Caza @Tiff_Caza
RT @edgarvlermamd: MT @NephJC @ericau PREDNOS: The authors concluded that an extended 16 week course of prednisolone did not reduce the rat…
Chia-shi Wang, MD, MSc @CWPedNephMD
Incredible effort. Confirms our trend and interest in evaluating shorter prednisone courses or alternative agents as "first-line"#nephjc
Nephrology Jrnl Club @NephJC
RT @edgarvlermamd: MT @NephJC @ericau PREDNOS: The authors concluded that an extended 16 week course of prednisolone did not reduce the rat…
Ajaya @Renaltubules
Now every reason to treat with either 4 wk + 4 Wk or 6 wk + 6 wk without worrying about extended period of treatment #nephjc
Nephrology Jrnl Club @NephJC
#nephJC
Michelle Rheault @rheault_m
@NephJC @drjosflynn I’d like to see trial of daily steroids until response, then QOD vs daily for fixed time. Like we use for relapses. Why not for first episode? #NephJC
Nephrology Jrnl Club @NephJC
RT @NephJC: @drjosflynn @rheault_m Which regimens would you ideally like to see tested/compared? #NephJC
Chia-shi Wang, MD, MSc @CWPedNephMD
@rheault_m @NephJC @drjosflynn there's our next trial. #nephjc
Nephrology Jrnl Club @NephJC
RT @drjosflynn: @NephJC Won't affect my practice b/c they did not test the regimen that most ppl seem to use - based on poll by @rheault_m.…
Nephrology Jrnl Club @NephJC
RT @rheault_m: @NephJC @drjosflynn I’d like to see trial of daily steroids until response, then QOD vs daily for fixed time. Like we use fo…
Michelle Starr @mcstarr1
@NephJC Don’t think there's a compelling reason to extend treatment. No change for me #NephJC
Nephrology Jrnl Club @NephJC
#NephJC
Michelle Rheault @rheault_m
@nephjc The Ped Nephs came out of the woodwork tonight! Strong showing all. #nephjc https://t.co/FT6RBc3s52
Nephrology Jrnl Club @NephJC
#NephJC
Nephrology Jrnl Club @NephJC
RT @mcstarr1: @NephJC Don’t think there's a compelling reason to extend treatment. No change for me #NephJC
Nephrology Jrnl Club @NephJC
RT @CWPedNephMD: @NephJC For now, sticking with standard course since there's no compelling reason to extend treatment.#NephJC
Pediatric Nephrology Research Consortium @thePNRC
@kidneytweets @BabyBeanDoc @NephJC Did somebody call?? #NephJC https://t.co/SzQdhIqUgA
Michelle Starr @mcstarr1
Nice work all! #nephjc
Nephrology Jrnl Club @NephJC
@rheault_m Great to see everyone joining today! #NephJC
Nephrology Jrnl Club @NephJC
Thanks for joining us today and for contributing to this discussion. #NephJC
Cathy Quinlan @KidneyCathy
Thanks everyone - hope our adult colleagues learned something about the wonders of paediatric nephrotic syndrome! #nephjc
Nephrology Jrnl Club @NephJC
Please join us for the #NephJC Asia chat at Wed 9:00 pm IST and Europe chat at Wed 9 pm BST
Nephrology Jrnl Club @NephJC
RT @NephJC: Please join us for the #NephJC Asia chat at Wed 9:00 pm IST and Europe chat at Wed 9 pm BST
Sami Alasfar @SamiAlasfar
@KidneyCathy I certainly did #NephJC
Nephrology Jrnl Club @NephJC
If you haven’t already, please sign up for our weekly newsletter https://t.co/5aumn8ImwF #NephJC
Michelle Rheault @rheault_m
@KidneyCathy @NephJC @drjosflynn #NephJC https://t.co/3poQnVBj53
AbePumpernickel🇺🇸 @abepumpernickel
RT @kidney_boy: Sorry I'm late. Doing Tech Support for my parents. Joel Topf, community nephrologist. Detroit Michigan. #nephJC
Nephrology Jrnl Club @NephJC
Want to get some #NephJC merchandise? Click here https://t.co/eOqYlnH0Ou
Nephrology Jrnl Club @NephJC
Goodbye everyone! #NephJC
Nephrology Jrnl Club @NephJC
@Kat1eJones @rheault_m Definitely come along! Hopefully more pediatric articles on #NephJC also
Joel Topf, MD FACP @kidney_boy
Impressive numbers: 318 Tweets. 82 Participants. 1,970,346 Impressions. June 24th 2019. More #NephJC 📊 here https://t.co/YAszPR9XVM via @symplur
Michelle Rheault @rheault_m
@Kat1eJones @NephJC It’s fun! Even when they discuss an adult article I don’t care about. #nephjc
Joseph Flynn @drjosflynn
RT @KidneyCathy: Thanks everyone - hope our adult colleagues learned something about the wonders of paediatric nephrotic syndrome! #nephjc
Michelle Rheault @rheault_m
@KLS_leeson @Kat1eJones @NephJC This is such a rare disease, it’s hard to believe health economics even matters. #NephJC
Juan Castellanos @cococast
RT @edgarvlermamd: Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8…
Michelle Rheault @rheault_m
@KidneyCathy @kidneytweets @NephJC What IS the circulating factor? #NephJC
Tathagata Bose @tbosex67
Tathagata Bose, India, no COI.. This is what we follow.. Indian Society of Pediatric Nephrology (ispn guidelines) #NephJC https://t.co/3o8jSIIxCx
Justin Davis @jbda19
RT @NephJC: Want to get some #NephJC merchandise? Click here https://t.co/eOqYlnH0Ou
Justin Davis @jbda19
RT @NephJC: If you haven’t already, please sign up for our weekly newsletter https://t.co/5aumn8ImwF #NephJC
Justin Davis @jbda19
RT @NephJC: Please join us for the #NephJC Asia chat at Wed 9:00 pm IST and Europe chat at Wed 9 pm BST
Fitsum Tilahun MD @fitse_t
@Bezatheo as you are the only pediatric nephrologist I know in #Ethiopia 🇪🇹 an tagging you here to check today's #nephjc
Nayra @NayraKqy
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
Swasti Chaturvedi @SwastiThinks
RT @NephJC: T3A: The authors concluded that an extended 16 week course of prednisolone did not reduce the rate of relapse compared to a sta…
Swasti Chaturvedi @SwastiThinks
RT @hswapnil: As @KidneyCathy pointed out - main result also is that 80% had a relapse Eventually #nephjc https://t.co/Vkw8NRFDmg
Swasti Chaturvedi @SwastiThinks
RT @rheault_m: @kidney_boy @StotterMD @NephJC We call this group “late steroid resistant”. Initially respond to steroids, then become resis…
Hillel Sternlicht, MD @ConceptsInHTN
RT @kidney_boy: Impressive numbers: 318 Tweets. 82 Participants. 1,970,346 Impressions. June 24th 2019. More #NephJC 📊 here https://t.co/YA…
abdelhamid Hamdy @abdelhamed012
RT @Renaltubules: When do you call Steroid resistant Nephrotic syndrome? - ours 4 week #nephjc
Ajaya @Renaltubules
Remission in Nephrotic syndrome depends on ? - Dose of prednisolone OR - Duration of treatment OR - Both dose and duration #NephJC #ipnajjc #eraedta
Bollam Rajesh @BollamRajesh4
RT @AbaRenua: Polls for far; 67% concerned of overcorrection when correcting hypernatraemia presumably neurological concerns. Let’s review…
Marvin Gonzalez @MarvinGonzlez16
Marvin Gonzalez, from Nicaragua. No COI. #nephJC #NSMC
Johndbaptist! @brosobio
RT @Renaltubules: Childhood Nephrotic facts -Incidence-2 per 100 000 children -Presents at median age of 2-3 years -Boys>Girls -More common…
DrAna_FamilyNameTooHardToPronounce🌈❤️🍒🤓 @PokrajacAna
RT @NephJC: T2D: For secondary outcomes, there were no differences in the mean number of relapses or the proportion developing frequently r…
Gregorio Romero González @Tubulocentric
RT @edgarvlermamd: Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8…
Saulo Fernández @saufdez
RT @edgarvlermamd: Investigations of glucocorticoid action in glomerulonephritis ca. 2017 from @JASN_News #Nephpearls #NephJC 👉🏼 https://t.…
BAPN @BAPNnephrology
The British and Europeans are coming! Join #nephjc @PREDNOS chat tonight 9pm BST https://t.co/v7z4LFmeuF
Michal Malina @DrMalinaM
@BAPNnephrology @PREDNOS Aren't British also Europeans? 🤔 😀 Looking fwd to the #nephjc
Eduardo @eduverdem
RT @edgarvlermamd: MT @NephJC @ericau PREDNOS: The authors concluded that an extended 16 week course of prednisolone did not reduce the rat…
Era Europa @Era_Europa
RT @JMGardnerMD: This one never gets old! Amazing photo by @BethBraunhut of membranous nephropathy. Looks at those spikes! #pathology #path
chakkra @chakkra3
RT @edgarvlermamd: Glucocorticoids in the treatment of glomerular diseases ca. 2018 from @CJASN #Nephpearls #NephJC 👉🏼 https://t.co/wn81b8…
Quique Montagud @QuimonMar
RT @Renaltubules: When do you call Steroid resistant Nephrotic syndrome? - ours 4 week #nephjc
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