#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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See #NephJC Influencers/Analytics.

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Dr Mukesh Rulaniya @RulaniyaDr
RT @edgarvlermamd: @srrezaie ✅ The myth of renal dose dopamine #RenalRules #Nephpearls #NephJC 👉🏼 https://t.co/xHHgHoiG2Q https://t.co/39AoW7Z9Fj
Dr Mukesh Rulaniya @RulaniyaDr
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
The Herrick Society @herricksociety
RT @frank_dor:
Dragon Fisting @dragon_fisting
SICK PEOPLE: Median SBP was 83 mmHg (IQR, 76-87 mm Hg) with a median lactate level of 4.3 mmol/L (IQR, 2.8-7.7 mmol/L). #nephjc
David Llantén @d_llanten
RT @hec_310:
Ibrahim Showaihi @showaihi
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Sue G @living_donor
RT @frank_dor:
Ana G. Robles @AnaAGRob
RT @hec_310:
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: You have to wonder how many other things we assume are helpful may not be or are even harmful? #nephjc
Willij Zuidema @WillijZuidema
RT @frank_dor:
Joel M. Topf, MD FACP @kidney_boy
RT @Nephro_Sparks: thanks to @ansakhuja for joining. @Errantnephron for writeup and @kidney_boy for moderating. #NephJC I learned that sepsis in Zambia is bad
Prof. Dr. Ayhan ÖZHASENEKLER @AOzhasenekler
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Fitz @fpgmanmd
RT @edgarvlermamd: Early Resuscitation Protocol ➡️ In-hospital Mortality in Adults w/ Sepsis & Hypotension 🇿🇲 #NephJC #Nephpearls 👉🏼 https://t.co/C3GbN47L3M https://t.co/64yqVCHUnr
özgür özen @ozgurozen80
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Joel M. Topf, MD FACP @kidney_boy
#NephJC ? https://t.co/wsuDb5hIUF
Ibrahim Shatat @pedsnephrology
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Sidney Erwin Manahan, MD 🇵🇭 @PhRheumaJr
Ideally for (insert intervention). However, due to (finances/ unavailability/ etc) and discussion with pt, will give (alternative int). https://t.co/Z2pyHZTWw5
EVER OLIVIE CIPRIANO @DREVEROLIVIE
RT @edgarvlermamd: Edgar Lerma, 🌧 Chicago-based Nephrologist #NephJC https://t.co/1NawWghiRv
Pano @ED_TRex
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Samir C Gautam @drsamirgautam
RT @edgarvlermamd: Early Resuscitation Protocol ➡️ In-hospital Mortality in Adults w/ Sepsis & Hypotension 🇿🇲 #NephJC #Nephpearls 👉🏼 https://t.co/C3GbN47L3M https://t.co/64yqVCHUnr
American Society of Pediatric Nephrology @ASPNeph
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Taryn Lloyd @JustLloydering
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Austin Jule @AJule450
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Mana @manasigh
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Dr L K Tripathi @lktr18
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Hemachandar @drhemachandarr
RT @anupampom: @NephJC EGDT is a story of medical reversal ..We should take all 'bundled' approaches with pinch of salt #nephjc https://t.co/NDCNkneipL
Andres Cadena @ctropicalis
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
#NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Chris Laing @drchrislaing
Great graphic team. Well done. Surprising results? Maybe needs further validation in other centres? I note 4 litres in fluid protocol https://t.co/T8PFA6my1T
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@drchrislaing Excellent points! There will be a discussion again in about 30 minutes on #NephJC - hope you can join?
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: #NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Chris Laing @drchrislaing
RT @hswapnil: @drchrislaing Excellent points! There will be a discussion again in about 30 minutes on #NephJC - hope you can join?
Chris Laing @drchrislaing
Why not https://t.co/ImYwxlhjLz
Nephrology Journal Club @NephJC
Half an hour until #NephJC Take a look at the visual abstract! https://t.co/m0fPgpSdKi
Nephrology Journal Club @NephJC
Join us for the europe/africa edition in 15 minutes?! #NephJC https://t.co/ONS835kC5J
Nathaniel Reisinger @nephrothaniel
RT @NephJC: #NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Nephrology Journal Club @NephJC
It’s 8pm GMT - Welcome to #NephJC
Nephrology Journal Club @NephJC
#NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Nephrology Journal Club @NephJC
I’m @drbstewart - Neph/med trainee in Cambridge, UK hosting tonight’s #NephJC
Nephrology Journal Club @NephJC
It can be helpful to use https://t.co/rFoH4MVMzu tchat.io or https://t.co/HkSJU7K32t to tune into #NephJC
Nephrology Journal Club @NephJC
Remember to include #NephJC to every tweet
Nephrology Journal Club @NephJC
Please introduce yourself, any COI, what do you do? #NephJC
Nephrology Journal Club @NephJC
Don't be shy! Even if you are lurking/spectating #NephJC
Nephrology Journal Club @NephJC
Anyone working in Zambia? #NephJC
Nephrology Journal Club @NephJC
Great crowd already! #NephJC
Nephrology Journal Club @NephJC
Stateside had fun with this last night #NephJC
Nephrology Journal Club @NephJC
Tonight we are talking about an RCT of fluid resuscitation in sepsis #NephJC
Nephrology Journal Club @NephJC
@errantnephron has written an excellent summary of the article: https://t.co/cySCXGpFjZ #NephJC
Nephrology Journal Club @NephJC
The paper is available on JAMA https://t.co/XCOazv3Yer #NephJC
Nephrology Journal Club @NephJC
Also shhhh but there may be a link... #NephJC https://t.co/1mHpQxdq4n
Nephrology Journal Club @NephJC
Unfortunately not #openaccess #NephJC
Nephrology Journal Club @NephJC
@Wamugwe @DrMattGB Welcome! #NephJC
Nephrology Journal Club @NephJC
Remember to include #NephJC with every tweet
Nephrology Journal Club @NephJC
Let's get cracking #NephJC
Nephrology Journal Club @NephJC
We’ve been sailing down the EGDT river for a long time - choppy waters recently #NephJC
Nephrology Journal Club @NephJC
3 important trials ProCESS, ARISE and ProMISe from different corners of the globe spelled bad news for EGDT #NephJC https://t.co/cwKwY8r5Fk
Nephrology Journal Club @NephJC
The FEAST study https://t.co/Zqvm9VUbZr argued against fluid boluses in paediatric sepsis. #NephJC
Nephrology Journal Club @NephJC
FEAST was conducted in sub-saharan Africa #NephJC Nice LIFTL review here: https://t.co/wrekz9MyXX
Florian Buchkremer @swissnephro
Hi guys, Florian Buchkremer, no COI, still reading... (thanks, Tom) #NephJC
Nephrology Journal Club @NephJC
@swissnephro Hi! #NephJC
Nephrology Journal Club @NephJC
Total classic amongst clinical trials youtube videos right here: https://t.co/NHYVbmrQkl #NephJC
Nephrology Journal Club @NephJC
#NephJC Great to have you with us https://t.co/HDZlQn75ft
Nephrology Journal Club @NephJC
The venue for this study is Zambia - only 10 ICU beds! #NephJC
Fiona Duthie @faiduthie
Hi, Fiona from Edinburgh, multitasking and haven't read manuscript so mainly lurking! #nephjc
Arkana Laboratories @arkanalabs
RT @NephJC: Tonight we are talking about an RCT of fluid resuscitation in sepsis #NephJC
Nephrology Journal Club @NephJC
So the stage is set for the simplified severe sepsis protocol (SSSP) study #NephJC
Nephrology Journal Club @NephJC
I think we can all agree it’s fantastic work from the investigators and people of Zambia to produce these data #NephJC
Nephrology Journal Club @NephJC
Ok - Let’s crunch the methods and cohort #NephJC
Nephrology Journal Club @NephJC
Study ran oct 2012 to nov 2013 #NephJC
Nephrology Journal Club @NephJC
RT @AKIfellow:
Nephrology Journal Club @NephJC
Included sepsis (infection +>=2SIRS) with SBP<=90 or MAP <=65 #NephJC
Nephrology Journal Club @NephJC
@toates_19 Haha great! #NephJC
Fiona Duthie @faiduthie
@DrMattGB Hmmmmm it got more complicated mid-July..! #nephjc
Nephrology Journal Club @NephJC
They excluded the hypoxic and tachypnoeic #NephJC
Nephrology Journal Club @NephJC
Pretty broad inclusion criteria - agree? #NephJC
Nephrology Journal Club @NephJC
Two arms SSSP (106) vs standard care (103) #NephJC
Nephrology Journal Club @NephJC
Here is the SSSP: #NephJC https://t.co/z9mmdyar3W
Nephrology Journal Club @NephJC
SSSP gives overall 4 litres in five hours 2:1, 2:4 #NephJC
Nephrology Journal Club @NephJC
they clearly recognise this is a fair bit! - screened for overload every hour #goodmedicine #NephJC
Paul Phelan @paulphel
Evening, Paul Phelan, Edinburgh what did I miss? #nephjc
Nephrology Journal Club @NephJC
@paulphel But reflective of their presenting population? #NephJC
Nephrology Journal Club @NephJC
@logiebear111 What’s up with excluding GI bleed without fever? #NephJC
Nephrology Journal Club @NephJC
Fluids were not weight adjusted- no weights in paper #NephJC
Nephrology Journal Club @NephJC
SSSP mandated stopping fluids if JVP>3cm #NephJC
Nephrology Journal Club @NephJC
SSSP stopped fluids if SpO2 fell 3% or RR increased >=5bpm #NephJC
Nephrology Journal Club @NephJC
SSSP also allows for the addition of dopamine for hypotension and transfusion for anaemia #NephJC
Nephrology Journal Club @NephJC
What are your thoughts on dopamine in this mix? #NephJC
Nephrology Journal Club @NephJC
209 patients - mostly HIV+ #NephJC
Nephrology Journal Club @NephJC
These patients were sick - I think we can agree #NephJC
Nephrology Journal Club @NephJC
Sick patients = HIV median CD4 <100 #NephJC
Nephrology Journal Club @NephJC
Sick patients = Positive cultures for TB #NephJC
Nephrology Journal Club @NephJC
Sick patients = Mean Hb 7.8g/dL #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@AKIfellow @Wamugwe @NephJC HIV numbers may not be representative of gen population, but may be of patients with sepsis/shock? #nephjc
Nephrology Journal Club @NephJC
Sick patients = Median alb 2.2g/dl #NephJC
Nephrology Journal Club @NephJC
Sick patients = average lactate >4 #NephJC
Nephrology Journal Club @NephJC
RT @AKIfellow:
Nephrology Journal Club @NephJC
Average age was 36.7 - thoughts on how this shifts things vs other EGDT trials ? #NephJC
Nephrology Journal Club @NephJC
The authors were using the SIRS criteria. This was '12-13 #NephJC
Nephrology Journal Club @NephJC
RT @DrMattGB:
Fiona Duthie @faiduthie
@logiebear111 @NephJC Ditto but better than nothing given resource issue... #nephjc
Nephrology Journal Club @NephJC
Importantly the average IV fluid input over 1st 6h <2l in standard care - too much, too little? #NephJC
Nephrology Journal Club @NephJC
Less than half of standard care grp received any fluid bolus #NephJC
Nephrology Journal Club @NephJC
Very unusual #NephJC https://t.co/oS8zdDgUsa
Nephrology Journal Club @NephJC
Vasopressors in <2% in standard care grp #NephJC
Nephrology Journal Club @NephJC
Not subtle difference in management approach I think we can agree? #NephJC
Nephrology Journal Club @NephJC
@AKIfellow Depends on the clinician's "standard care" #NephJC
Nephrology Journal Club @NephJC
@toates_19 @logiebear111 Or post surgical abdominal sepsis disasters #IBD etc. #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@drchrislaing Sorry: just tweet with hashtag #NephJC Or go to https://t.co/zpxswszfWz
Nephrology Journal Club @NephJC
@DrMattGB @alehkir Malnourished TB and HIV in the cohort probably doesn't make for a very effective LV #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
#NephJC https://t.co/PANqvFvm4h
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
#NephJC https://t.co/f2UPoXw2Es
Nephrology Journal Club @NephJC
@toates_19 @DrMattGB @AKIfellow Sounds like kwashiorkor territory? #NephJC
Nephrology Journal Club @NephJC
Let’s talk results #NephJC - pretty clear cut!
Nephrology Journal Club @NephJC
Primary outcome was in hospital mortality #NephJC
Nephrology Journal Club @NephJC
Secondary outcome: 28-day mortality and time to death #NephJC
Nephrology Journal Club @NephJC
Bottom line: SSSP does harm - 48% in hospital mortality vs 33% for standard care #NephJC https://t.co/LySmplizbS
Nephrology Journal Club @NephJC
Please tag tweets with #NephJC
Nephrology Journal Club @NephJC
#NephJC https://t.co/T6UwOheJFd
Nephrology Journal Club @NephJC
Bottom line: SSSP does harm - 67% 28 day mortality vs 45% for standard care #NephJC
Nephrology Journal Club @NephJC
Nearly 70% pts died by 28 days! Let that sink in... #NephJC
Nephrology Journal Club @NephJC
Number needed to Harm is 6 for in hospital mortality and 4 for 28 day mortality #NephJC
Nephrology Journal Club @NephJC
Remember: only one patient made it to the ICU #NephJC
Nephrology Journal Club @NephJC
@neilturn @AKIfellow Particularly on the back of mounting (-) literature on EGDT #NephJC
Nephrology Journal Club @NephJC
Anyone willing to trot out reasons why we can ignore these results? #NephJC https://t.co/uXNQktIHR3
Nephrology Journal Club @NephJC
Is this harm all down to mostly volume? mostly dopamine? cocktail? Something great in standard care? #NephJC
Nephrology Journal Club @NephJC
#NephJC https://t.co/IE1nI5CwQ7
Nephrology Journal Club @NephJC
@AKIfellow @Dr_Beale_ @neilturn Tyranny of distance also #NephJC
Nephrology Journal Club @NephJC
Results in full detail - pretty clear evidence of harm overall #NephJC https://t.co/jBG6jUvvtk
Nephrology Journal Club @NephJC
K-M curve tells story of 2ndry endpoint #NephJC https://t.co/vHncQWbPQt
Fiona Duthie @faiduthie
@logiebear111 @toates_19 @NephJC Pulmonary oedema or ARDS? Anyone know if ards is less common in hiv given it's an inflammatory illness..? Maybe not the issue... #nephjc
Nephrology Journal Club @NephJC
Single centre - #FEAST went all over SSafrica ... would the results have changed? #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @neilturn:
Nephrology Journal Club @NephJC
@toates_19 With albumin that low, there's rationale for giving fluid that stays put? #NephJC
Nephrology Journal Club @NephJC
If you designed this study - what other end points would you want to include? #NephJC
Chris Laing @drchrislaing
#nephjc 4 litres seems a lot
Nephrology Journal Club @NephJC
SSSP gives overall 4 litres in five hours 2:1, 2:4 #NephJC https://t.co/fYcydcrC2r
Nephrology Journal Club @NephJC
Ok 10 minutes left - Any further ideas about where the paper leaves us? #NephJC
Nephrology Journal Club @NephJC
#NephJC how will this change your management?
Nephrology Journal Club @NephJC
Will you be "keeping 'em dry"? #NephJC https://t.co/WOZJZ8mroL
Chris Laing @drchrislaing
#nephjc none of the major GDT NEJM trials have reduced severe AKI rates. I guess what is surprising here is adverse outcome?
Nephrology Journal Club @NephJC
@WhistlingDixie4 thanks for joining! See you again #NephJC
Chris Laing @drchrislaing
#nephjc @toates_19 like many things in life with fluids "timing is everything"
Nephrology Journal Club @NephJC
@toates_19 Fluids = drugs with benefits and harms #NephJC (though not really any benefits here!)
Nephrology Journal Club @NephJC
Any final ideas about this paper? #NephJC
Dr. HattaN BojaN I د. هتان بوجان @hattanbojan
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
About time to draw to close - Thanks all for joining in - really enjoyed this #NephJC chat!
Nephrology Journal Club @NephJC
Absolutely this should be #openaccess #NephJC https://t.co/MezbddTSSi
Nephrology Journal Club @NephJC
Thanks for joining this #NephJC - this is @drbstewart signing off!
Chris Laing @drchrislaing
#nephjc don't forget with the big sepsis GDT trials "standard care" was not unrecognised sepsis/no action. Lack of evidence is around GDT
Chris Laing @drchrislaing
Another great graphic from the #NephJC team https://t.co/LEPf2q7LbT
Matthew Sparks, MD @Nephro_Sparks
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @neilturn:
Matthew Sparks, MD @Nephro_Sparks
fantastic stuff #NephJC https://t.co/R5HMQXVkDw
Gail Rae-Garwood @Slowitdownckd
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Michelle Rheault @rheault_m
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Jerad Gardner, MD @JMGardnerMD
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Jerad Gardner, MD @JMGardnerMD
#NephJC was a major inspiration for #pathJC. Our neph colleagues helped us a lot when starting the #pathology Twitter journal club! https://t.co/ghv5YkTxsx
YNP of ERA @ynptweets
RT @NephJC: I love me some Table 1! #NephJC https://t.co/zGBSQI0drS
YNP of ERA @ynptweets
RT @drchrislaing: Another great graphic from the #NephJC team https://t.co/LEPf2q7LbT
Sibel Gokcay Bek @sibgokcay
RT @NephJC: #NephJC chat tonight/tomorrow Summary: https://t.co/NAbvetvGSo Full text: https://t.co/lFTvhvOign #VisualAbstract : https://t.co/mHEtv2QYnr
Martín Vargas 🇲🇽 @MartinVargas89
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
MJ (Marietjie) Slabbert Keilty 🚁 🐈‍⬛ @Gas_Air_CCdoc
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Natalie Lavergne @LavergneNatalie
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
John P Erwin III MD FACC @HeartOTXHeartMD
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Dr.Carlos Fernandez Pereira @dr_cfp
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Jonathan Britton @JonTheMedic
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
#NephJC content from Twitter.