#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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See #NephJC Influencers/Analytics.

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Annabel Biruete 🇲🇽 @anniebelch
And, Dr. Jans Titze is here! Talking about balancing wobbles in sodium in Neptune room. Good way to get ready for #NephJC #ERAEDTA17
Annabel Biruete 🇲🇽 @anniebelch
6. Water intake does not match sodium intake either #NephJc #ERAEDTA17 https://t.co/oqnTg7XTKj
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Excellent thread, on Dr Titze's talk at #ERAEDTA17, as preamble to this week's #NephJC https://t.co/ZS8zGMPKqZ https://t.co/a488jWYujB
Thahir @docthahir
RT @hswapnil: Excellent thread, on Dr Titze's talk at #ERAEDTA17, as preamble to this week's #NephJC https://t.co/ZS8zGMPKqZ https://t.co/a488jWYujB
Potomac Health @PHAInc
VA announces #BAA ($$$) for private sector/non-profits/universities innovations in #Kidney #KidneyDisease #NephJC https://t.co/QInu6L9O8h
Mana @manasigh
RT @hswapnil: Excellent thread, on Dr Titze's talk at #ERAEDTA17, as preamble to this week's #NephJC https://t.co/ZS8zGMPKqZ https://t.co/a488jWYujB
Matthew Sparks, MD @Nephro_Sparks
⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
ERA - European Renal Association @ERAkidney
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
RT @hswapnil: Excellent thread, on Dr Titze's talk at #ERAEDTA17, as preamble to this week's #NephJC https://t.co/ZS8zGMPKqZ https://t.co/a488jWYujB
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
Joel M. Topf, MD FACP @kidney_boy
RT @anniebelch: And, Dr. Jans Titze is here! Talking about balancing wobbles in sodium in Neptune room. Good way to get ready for #NephJC #ERAEDTA17
Matthew Sparks, MD @Nephro_Sparks
You mean Mars room 🤔 #eraedta17 https://t.co/qp2e9Y1Q1Q
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
Mayuri Trivedi @MayuriTrivedi80
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
Dr Aidan Baron @Aidan_Baron
RT @Rx_Ed: #HIV is more deleterious to the kidneys than #diabetes. And folks with both HIV and diabetes (very common) have the WORST prognosis. #NephJC https://t.co/3KJ9dvaEdE
Lucy Hindle @LucyHindle1
RT @Rx_Ed: #HIV is more deleterious to the kidneys than #diabetes. And folks with both HIV and diabetes (very common) have the WORST prognosis. #NephJC https://t.co/3KJ9dvaEdE
Joel M. Topf, MD FACP @kidney_boy
First draft of #VisualAbstract for tomorrow's #NephJC. Feedback welcomed. This is my worst first draft. Complex study. #TooManyWords https://t.co/WEsOMN4XWm
Nathaniel Reisinger @nephrothaniel
RT @kidney_boy: First draft of #VisualAbstract for tomorrow's #NephJC. Feedback welcomed. This is my worst first draft. Complex study. #TooManyWords https://t.co/WEsOMN4XWm
Annabel Biruete 🇲🇽 @anniebelch
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
@Nephronline: Invite patients to the meetings + policy formation so that #patientcare is designed for them #nephJC https://t.co/UKcFJn9VAp
Andrew M. Ibrahim MD, MSc (He/Him) @AndrewMIbrahim
RT @kidney_boy: First draft of #VisualAbstract for tomorrow's #NephJC. Feedback welcomed. This is my worst first draft. Complex study. #TooManyWords https://t.co/WEsOMN4XWm
Gates Colbert, MD @DoctorGates
Tomorrow @ #NephJC we will be talking Mars, Russians, salt, fluid collections, and isolation zones. Sound familiar? #NSMC #Salt https://t.co/J7Jcdgc9lp
Matthew Sparks, MD @Nephro_Sparks
RT @DoctorGates: Tomorrow @ #NephJC we will be talking Mars, Russians, salt, fluid collections, and isolation zones. Sound familiar? #NSMC #Salt https://t.co/J7Jcdgc9lp
Joel M. Topf, MD FACP @kidney_boy
@NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Ernesto LopezAlmaraz @kidney_doctor
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Andrew M. Ibrahim MD, MSc (He/Him) @AndrewMIbrahim
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
محذوف @milardport
RT @DoctorGates: Tomorrow @ #NephJC we will be talking Mars, Russians, salt, fluid collections, and isolation zones. Sound familiar? #NSMC #Salt https://t.co/J7Jcdgc9lp
Wings Implied @Wingsimplied
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Nephrology Journal Club @NephJC
Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Manuel Marquez (he/him) 👨🏻‍⚕️🇲🇽 🥗 @Kidney_Power
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Nathaniel Reisinger @nephrothaniel
RT @NephJC: Does increased Sodium intake truly cause increased Water intake? https://t.co/w3WxDtaHT8 #NephJC
Kenar Jhaveri @kdjhaveri
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Franklin Loachamin @FranLoachamin
RT @Nephro_Sparks: ⚡️ “Dr. Titze's Balancing Wobbles in Tissue Sodium” by @anniebelch #eraedta17 #NephJC #NSMC https://t.co/eqnunBP079
HofNorthwell Kidney @HofstraKidney
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
HofNorthwell Kidney @HofstraKidney
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Journal of Clinical Investigation @jclinicalinvest
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Healthcare Hashtag Project @healthhashtags
New Health Hashtag 👉 #ERAEDTA18 https://t.co/Ln7QrDKO3K 👏 @ERAEDTA #nephjc "55th ERA-EDTA Congress"
ChristosArgyropoulos MD, PhD PharmanukerInChief @ChristosArgyrop
RT @DoctorGates: Tomorrow @ #NephJC we will be talking Mars, Russians, salt, fluid collections, and isolation zones. Sound familiar? #NSMC #Salt https://t.co/J7Jcdgc9lp
Doc Maia @nephgirlsketch
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
ERA - European Renal Association @ERAkidney
RT @healthhashtags: New Health Hashtag 👉 #ERAEDTA18 https://t.co/Ln7QrDKO3K 👏 @ERAEDTA #nephjc "55th ERA-EDTA Congress"
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
#NephsWhoLead @DaVitaDoc
RT @NephJC: Is everything we know about sodium physiology wrong? #NephJC discusses the @JClinicalInvest study https://t.co/qqRAPdqTMb
Nephrology Journal Club @NephJC
#NephJC June 6/7 Article https://t.co/Klo3HNzZEW @jclinicalinvest Summary https://t.co/w3WxDtaHT8 #VisualAbstract https://t.co/vaKAbpBOxQ
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: #NephJC June 6/7 Article https://t.co/Klo3HNzZEW @jclinicalinvest Summary https://t.co/w3WxDtaHT8 #VisualAbstract https://t.co/vaKAbpBOxQ
Journal of Clinical Investigation @jclinicalinvest
RT @NephJC: #NephJC June 6/7 Article https://t.co/Klo3HNzZEW @jclinicalinvest Summary https://t.co/w3WxDtaHT8 #VisualAbstract https://t.co/vaKAbpBOxQ
Michelle Rheault @rheault_m
What does Mars have to do with sodium and tonight's #nephJC? Confession: I have no idea. https://t.co/ougnrxE2g7
Michelle Rheault @rheault_m
But I promise I'll read the paper by 9 EST so I'm ready to discuss. Join us! https://t.co/J1iRq4DYnC
Mira Krendel @KidneyMyosin
@rheault_m This is such an interesting study and a great summary, looking forward to the #NephJC . Here is the Mars connection. https://t.co/GNbnZyO8kz
Mira Krendel @KidneyMyosin
RT @rheault_m: What does Mars have to do with sodium and tonight's #nephJC? Confession: What does Mars have to do with sodium and tonight's #nephJC? Confession: I have no idea. https://t.co/ougnrxE2g7
Wings Implied @Wingsimplied
RT @rheault_m: What does Mars have to do with sodium and tonight's #nephJC? Confession: What does Mars have to do with sodium and tonight's #nephJC? Confession: I have no idea. https://t.co/ougnrxE2g7
Wings Implied @Wingsimplied
RT @KidneyMyosin: @rheault_m This is such an interesting study and a great summary, looking forward to the #NephJC . Here is the Mars connection. https://t.co/GNbnZyO8kz
Navdeep Tangri @NavTangri
RT @kidney_boy: @NephJC The #VIsualAbstract for this weeks #NephJC: @NephJC The #VIsualAbstract for this weeks #NephJC: How does salt intake affect water intake and what does that mean for metabolism. https://t.co/aSOPlxeOgP
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
@crickethealth is on the side of angels + needs #healthcare policies to make their model sustainable! #nephJC #ckd #dialysis #esrd https://t.co/8YTBRRtugm
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
@dsgold: the field of #nephrology would greatly benefit #dialysis + #kidney #transplant recipients Untapped opportunity #nephJC #hcldr https://t.co/2luGo8ziqc
Michelle Rheault @rheault_m
Ok, not a good sign when I have to start looking up words for #nephJC. "Infradian" means:
Nephrology Journal Club @NephJC
60 minutes for tonight's #NephJC Not too late to catch up. https://t.co/m2RafMHOm7
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: 60 minutes for tonight's #NephJC Not too late to catch up. https://t.co/m2RafMHOm7
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @rheault_m: Ok, not a good sign when I have to start looking up words for #nephJC. "Infradian" means:
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
RT @NephJC: #NephJC June 6/7 Article https://t.co/Klo3HNzZEW @jclinicalinvest Summary https://t.co/w3WxDtaHT8 #VisualAbstract https://t.co/vaKAbpBOxQ
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Fabulous summary by Joel @kidney_boy: https://t.co/ZS8zGMPKqZ no excuse not to read & join tonight #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@rheault_m funny how we learn new words. TEMPO gave me 'pollakiuria' ... #nephjc
Nephrology Journal Club @NephJC
This study is humdinger. Going to pour myself a coffee, feel free to talk among yourselves #nephjc
Matthew Sparks, MD @Nephro_Sparks
Matt Sparks @DukeKidney APD no COI #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC how long will it take the caffeine to come out from....or does it get retained? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Swapnil Hiremath #NephJC cofounder from @ottawacity @OttawaRenal Measure 24 hour Na/K all the time! No other CoI https://t.co/uD3VTVMdTu
Anna Burgner MD MEHP @anna_burgner
Anna Burgner, APD at @VUMCKidney, No COI #nephjc
Nephrology Journal Club @NephJC
It’s 9 PM Tuesday. Welcome to this edition of #NephJC
Nephrology Journal Club @NephJC
I'm Joel Topf, @Kidney_Boy and I will be hosting tonight's chat on the world shaking sodium article in JCI #NephJC
Nephrology Journal Club @NephJC
While we wait for everyone to arrive, please introduce yourselves and reveal any relevent conflicts of interest (COI) #NephJC
Matthew Sparks, MD @Nephro_Sparks
@hswapnil @ottawacity @OttawaRenal Hi Swap #NephJC
Nephrology Journal Club @NephJC
What would a COI even look like for this study? I work for Morton's Salt? #nephjc
Matthew Sparks, MD @Nephro_Sparks
@SLeonMD Hi Scherly #NephJC
Roger Rodby @NephRodby
Roger Rodby, Rush Chicago, no COI except big fan of salt on food #nephjc
Nephrology Journal Club @NephJC
No relevent COI, but I wanted to be an astronaut when I was a kid #NephJC
Matthew Sparks, MD @Nephro_Sparks
@anna_burgner @VUMCKidney Hi Anna #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@Nephro_Sparks Hey Matt!, hey Anna , Scherly. Rodby is in the house #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Nice to join in for my first #NephJC Interesting paper getting a lot of press
Anna Burgner MD MEHP @anna_burgner
Hi Matt, Swap, and Joel! #nephjc
Gates Colbert, MD @DoctorGates
Dallas based Nephrologist. #NSMC 2017. Saline pusher. #nephjc
Nephrology Journal Club @NephJC
Thanks for coming paul #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@PaulAWelling1 fabulous, thanks for joining! #nephjc
Nephrology Journal Club @NephJC
Hey gates and anna #nephjc
Matthew Sparks, MD @Nephro_Sparks
@NephRodby Here we go #RushRenalRules at #NephJC hint hint
Michelle Rheault @rheault_m
@NephJC Michelle here. Just managed to lose my copy of the paper in a stack of kid papers brought home for end of school year. #NephJC
Charbel C Khoury @Charbel_Khoury
Charbel Khoury, Renal Fellow, Clinical nutrition fellow, MGH/BWH, no COI. Hi everyone! #nephjc
Matthew Sparks, MD @Nephro_Sparks
@PaulAWelling1 Yes Dr Welling is joining #NephJC
Nephrology Journal Club @NephJC
Raise your hand if you could explain free water clearance to a high school student (sheepishly puts hands in his pocket) #nephjc
Anna Burgner MD MEHP @anna_burgner
@PaulAWelling1 So glad you could join us!!! #nephjc
Joshua Schwimmer, MD @joshuaschwimmer
Joshua, Nephrologist. #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Michelle, Charbel, Gates - and Szymon! (what time?) #nephjc
Nephrology Journal Club @NephJC
Hey Josh! #nephjc
Matthew Sparks, MD @Nephro_Sparks
@rheault_m @NephJC Lol Michelle #NephJC
Nephrology Journal Club @NephJC
Remember to add #NephJC to every tweet you want to be part of the discussion and recorded in the journal club archive.
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@joshuaschwimmer Nice to see you! Welcome back! #nephjc
Matthew Sparks, MD @Nephro_Sparks
@Charbel_Khoury See you soon Charbel #NephJc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@joshuaschwimmer Nice to see you! Welcome back! #nephjc
Nephrology Journal Club @NephJC
We recommend using tchat.io or https://t.co/rFoH4MVMzu. They filter out everything but the hashtag and add #NephJC to every tweet
Nephrology Journal Club @NephJC
@rheault_m printed studies, how quaint #nephjc
Nephrology Journal Club @NephJC
Nice! RT @brzoskos: @NephJC 3AM, just gave a kiss to my 4 weeks old son :) #nephjc
Matthew Sparks, MD @Nephro_Sparks
@khaled1409 Hi Khaled #NephJc
Brian Stotter, MD @StotterMD
Hello #nephjc! Brian Stotter, peds renal fellow, Boston. COI: I'm eating homemade gravlax during this salt discussion https://t.co/N5iIby3nCT
Matthew Sparks, MD @Nephro_Sparks
RT @StotterMD: Hello #nephjc! Brian Stotter, peds renal fellow, Boston. COI: Hello #nephjc! Brian Stotter, peds renal fellow, Boston. COI: I'm eating homemade gravlax during this salt discussion https://t.co/N5iIby3nCT
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@khaled1409 Hi Khaled, welcome to #NephJC
Nephrology Journal Club @NephJC
@StotterMD Nice! #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@StotterMD heh! Welcome - nice CoI #nephjc
Nephrology Journal Club @NephJC
#NephJC is a great way to build your personal learning network, so punch that follow button early and often!
Nephrology Journal Club @NephJC
Just Punch It! https://t.co/WTusn7Yx2W #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@Wagner_Nephro great to see you Brent! #nephjc
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
Hector Madariaga. From #PatriotsNation. No COI. Doing baby duties; trying to type and holding/feeding a baby 😃 #NephJC #multitasking
B. Wagner, M.D. 🇺🇸 @Wagner_Nephro
@hswapnil @Wagner_Nephro Ditto. #nephjc
Ivy Melgarejo @IvyM808
Hello! Im Ivy, medical resident from Honolulu. Nephrology wannabe. No COI, except we love Spam in Hawaii. #nephjc
Nephrology Journal Club @NephJC
Thank god you're here. We'll need real physiologists to get through this one MT @Wagner_Nephro: program director UTHSC San Antonio #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@IvyM808 awesome! Welcome to #NephJC...what time is it? #nephjc
Nephrology Journal Club @NephJC
@IvyM808 Awesome! thanks for coming. And it's pork shoulder, not SPAM! #nephjc
Ivy Melgarejo @IvyM808
@hswapnil @IvyM808 Hi! Its 3PM here in paradise. #nephjc
Nephrology Journal Club @NephJC
First follow of the day! RT @IvyM808: Hello! Im Ivy, medical resident from Honolulu. Nephrology wannabe. No COI... #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Edgar Lerma, Chicago-based Nephrologist #NephJC https://t.co/HLEzfXPeQK
Nephrology Journal Club @NephJC
This is our second article from the hallowed pages of JCI: https://t.co/j6MZmaH6Za #NephJC
Nephrology Journal Club @NephJC
The article is open access at: https://t.co/Klo3HNzZEW #nephjc
Nephrology Journal Club @NephJC
It's just 10 pages (2 pages of references) but don't miss the 1,131 page online supplement. #NephJC
Mira Krendel @KidneyMyosin
Mira Krendel, cell biologist, SUNY Upstate, lurking for #nephjc . No COI other than owning a Russian cosmonaut figurine. :) https://t.co/78cPDRY2NI
Roger Rodby @NephRodby
@IvyM808 https://t.co/UKfjC4GZun #nephjc
Nephrology Journal Club @NephJC
1,131 pages WTF #nephjc
Les @LBEBEN
New to this. Why can't I wash out my phosphorous retainers without making them angry? Why is more time unacceptable? https://t.co/KF6iwVPn13
Michelle Rheault @rheault_m
@IvyM808 Welcome Ivy! We love spam in MN too. You'll fit right in. #NephJC https://t.co/xMfeStAROd
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@KidneyMyosin welcome! great CoI! #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@LBEBEN Don't forget the hashtag! #NephJC
Michelle Rheault @rheault_m
RT @NephJC: It's just 10 pages (2 pages of references) but don't miss the 1,131 page online supplement. #NephJC
Ivy Melgarejo @IvyM808
@NephJC @IvyM808 Ooops, didn't know that! I guess kalua pork might be better. #nephjc
Nephrology Journal Club @NephJC
@KidneyMyosin Nice cosmonaut, I'll see your figure and raise you one pop song about Yuri Gargarin https://t.co/zycgXMwrDZ #nephjc
Matthew Sparks, MD @Nephro_Sparks
@IvyM808 Hi Ivy.. .welcome back #nephjc
Nephrology Journal Club @NephJC
T0: On a scale of "Fake News" to "I belive in Gravity", how certain were you than Na in = Na out? #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
How does salt intake affect water intake⁉️ #VisualAbstract by @kidney_boy #NephJC #Nephpearls https://t.co/R3nxSjzBul https://t.co/ooVzSDmwv5
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
@KidneyMyosin Welcome! How's Syracuse? Still cold? Say hi to Dr Narsipur for me! :) #nephjc
Roger Rodby @NephRodby
@NephJC I believe in gravity #nephjc
Nephrology Journal Club @NephJC
T0: On a scale of "Fake News" to "I believe in Gravity", how certain were you than Na in = Na out? #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@kidney_boy The Great SALT Debate from @NEJM #Nephpearls #NephJC https://t.co/U11mPsP1iC via @youtube
Matthew Sparks, MD @Nephro_Sparks
T0- I believe in gravity #nephjc
Nephrology Journal Club @NephJC
Me too RT @Nephro_Sparks: T0- I believe in gravity #nephjc
Ivy Melgarejo @IvyM808
@NephRodby @IvyM808 Yup, thats exactly how we like it. :) #nephjc
Gates Colbert, MD @DoctorGates
I think all of us have read the Supplement, just like all our legislators read the bills they pass #nephjc
Roger Rodby @NephRodby
Steady state is is about as basic a tenet that there is in nephrology #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
T0: Strong believer. Gravity level. https://t.co/jUxUA0ZKgT gave me some doubts way back, but only for a few seconds #nephjc
Nephrology Journal Club @NephJC
RT @DoctorGates: I think all of us have read the Supplement, just like all our legislators read the bills they pass #nephjc
Charbel C Khoury @Charbel_Khoury
T0- "I believe in Gravity" when on earth #nephjc
Brian Stotter, MD @StotterMD
@DoctorGates Or how we all read the Apple TOS #nephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: T0: T0: On a scale of "Fake News" to "I believe in Gravity", how certain were you than Na in = Na out? #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
The study shows Na in = Na out #nephjc
Matthew Sparks, MD @Nephro_Sparks
RT @NephRodby: Steady state is is about as basic a tenet that there is in nephrology #nephjc
Ivy Melgarejo @IvyM808
@rheault_m @IvyM808 Sounds great! Thank you! #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Background: To maintain osmotic balance, the body must gain ~333 ml of water for every 3gm increase in dietary salt (NaCl). #nephjc
Roger Rodby @NephRodby
https://t.co/8fs2silHM4 #nephjc
Matthew Sparks, MD @Nephro_Sparks
RT @PaulAWelling1: The study shows Na in = Na out #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: Steady state is is about as basic a tenet that there is in nephrology #nephjc
Nephrology Journal Club @NephJC
Absolutely, unless you only measure for 24-48 hrs RT @PaulAWelling1: The study shows Na in = Na out #nephjc #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@Nephro_Sparks Did you say gravity 🚀 ⁉️ #NephJC https://t.co/sVznn74dR2
Nephrology Journal Club @NephJC
The question in the study stems from the observation that Na is rhythmicly stored and released on a weekly and monthly cycle. #NephJC
Nephrology Journal Club @NephJC
I had never heard of that. You? #NephJC
Peter Suzman @Biomaven
Really interesting. https://t.co/e7RJjY8acU
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
T0: I believe in gravity #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: The question in the study stems from the observation that Na is rhythmicly stored and released on a weekly and monthly cycle. #NephJC
Matthew Sparks, MD @Nephro_Sparks
RT @edgarvlermamd: @Nephro_Sparks Did you say gravity 🚀 ⁉️ #NephJC https://t.co/sVznn74dR2
Brian Stotter, MD @StotterMD
Could make a bad Wicked reference right now #nephJC
Michelle Rheault @rheault_m
@NephJC I think you mean cycle with an "Infradian" rhythm. #NephJC
Roger Rodby @NephRodby
@NephJC crazy how Na has this extra-extracellular storage #nephjc
Anna Burgner MD MEHP @anna_burgner
@NephJC I had never heard of that before, I guess I need to pay more attention at research conference! #nephjc
Nephrology Journal Club @NephJC
this word, I do not know what it means RT @rheault_m: @NephJC I think you mean cycle with an "Infradian" rhythm. #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: The question in the study stems from the observation that Na is rhythmicly stored and released on a weekly and monthly cycle. #NephJC
Nephrology Journal Club @NephJC
Sodium is apparently released when cortisol is at its peak and aldosterone is at its trough #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Renal Physiology 101: Regulators of renal Na excretion #Nephpearls #NephJC 👉🏼 https://t.co/qaIE4wl9ac https://t.co/nfOiOODGSL
Nephrology Journal Club @NephJC
Since these hormones rise and fall on a weekly cycle, 24- or 48- hour balance studies are inadequate #NephJC
Nephrology Journal Club @NephJC
Topic 1: Methods #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @PaulAWelling1: The study shows Na in = Na out #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: Absolutely, unless you only measure for 24-48 hrs RT @PaulAWelling1: Absolutely, unless you only measure for 24-48 hrs RT @PaulAWelling1: The study shows Na in = Na out #nephjc #nephjc
Nephrology Journal Club @NephJC
The simulated Mars missions Mars105 and Mars 520 provided a unique opportunity to do prolonged metabolic balance studies #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@anna_burgner @NephJC ahem! or your colleagues https://t.co/qfyPSj5NXV ;-) #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @NephRodby: Steady state is is about as basic a tenet that there is in nephrology #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @PaulAWelling1: Background: Background: To maintain osmotic balance, the body must gain ~333 ml of water for every 3gm increase in dietary salt (NaCl). #nephjc
Michelle Rheault @rheault_m
RT @NephJC: The simulated Mars missions Mars105 and Mars 520 provided a unique opportunity to do prolonged metabolic balance studies #NephJC
Nephrology Journal Club @NephJC
Wikipedia has a nice page about the Simulated Mars Mission #NephJC https://t.co/2Ps13jDfKj
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Sodium is apparently released when cortisol is at its peak and aldosterone is at its trough #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@kidney_boy Evolution of food in space 🚀 #NephJC https://t.co/sOrp2dthdF
Nephrology Journal Club @NephJC
During the Mars missions, the diets were cycled from 12 g to 9 g to 6 gram salt. Each salt level was maintaned for at least 29 days. #NephJC
Matthew Sparks, MD @Nephro_Sparks
Had a patient ask me about this study #nephjc
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
RT @NephJC: The question in the study stems from the observation that Na is rhythmicly stored and released on a weekly and monthly cycle. #NephJC
Anna Burgner MD MEHP @anna_burgner
@hswapnil @NephJC Yeah that's what I meant, need to listen better while they are talking at conference!! :-) #nephjc #ISwearIWasntNapping
Anna Burgner MD MEHP @anna_burgner
@Nephro_Sparks wow! what was their question? Can I eat more salt? #NephJC
Michelle Rheault @rheault_m
@NephJC Was the salt content blinded? I couldn't tell from methods. Could influence water intake?? #NephJC
Nephrology Journal Club @NephJC
You told them it was just Russian Hackers trying to ruin physiology? RT @Nephro_Sparks: Had a patient ask me about this study #nephjc
Fred Wu, MD 🫀 吳明杰 @FredWuMD
RT @PaulAWelling1: Background: Background: To maintain osmotic balance, the body must gain ~333 ml of water for every 3gm increase in dietary salt (NaCl). #nephjc
Nephrology Journal Club @NephJC
good question. Not addressed RT @rheault_m: @NephJC Was the salt content blinded? I couldn't tell from methods. #NephJC
Matthew Sparks, MD @Nephro_Sparks
said- tune in to #NephJC
Nephrology Journal Club @NephJC
Always the right answer! RT @Nephro_Sparks: said- tune in to #NephJC
Nephrology Journal Club @NephJC
Urine output, water intake and dietary compliance were carefully measured and recorded #NephJC
Nephrology Journal Club @NephJC
They stratified the 24 hour urine sodium measurements in every dietary group into tertiles #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Methods: Fluid intake measured and self reported #nephjc
Matthew Sparks, MD @Nephro_Sparks
I seriously did RT @Nephro_Sparks: said- tune in to #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: During the Mars missions, the diets were cycled from 12 g to 9 g to 6 gram salt. Each salt level was maintaned for at least 29 days. #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: Urine output, water intake and dietary compliance were carefully measured and recorded #NephJC
Gates Colbert, MD @DoctorGates
Do you think when USA does this Mars study we will be "Merica and go for 24g? Location #Area51 #nephjc
Nephrology Journal Club @NephJC
What I meant by stratified and then tertiled #NephJC https://t.co/ctEyUVkalZ
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: They stratified the 24 hour urine sodium measurements in every dietary group into tertiles #NephJC
Nephrology Journal Club @NephJC
That will be the low salt group MT @DoctorGates: Do you think when USA does this Mars study we will be "Merica and go for 24g? #nephjc
Nephrology Journal Club @NephJC
They likewise stratified the aldo and cortisol levels into tertiles for each diet group #NephJC
Nephrology Journal Club @NephJC
I am a bit uncomfortable with this post hoc stratification. That bother anyone else? #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: They likewise stratified the aldo and cortisol levels into tertiles for each diet group #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Right. And fluid intake unrestricted RT @PaulAWelling1: Methods: Fluid intake measured and self reported #nephjc #nephjc
Bobby Foulcamp @bobby_foulcamp
RT @edgarvlermamd: Renal Physiology 101: Renal Physiology 101: Regulators of renal Na excretion #Nephpearls #NephJC 👉🏼 https://t.co/qaIE4wl9ac https://t.co/nfOiOODGSL
Nephrology Journal Club @NephJC
Fluid intake had to be unrestricted, it was an outcome of the study #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @rheault_m: @NephJC Was the salt content blinded? I couldn't tell from methods. Could influence water intake?? #NephJC
Matthew Sparks, MD @Nephro_Sparks
for mouse metabolic cage studies food and water given as gel. #nephjc
Matthew Sparks, MD @Nephro_Sparks
bacon flavored and capped at 10g gel food per 24hrs #nephjc
Michelle Rheault @rheault_m
@NephJC Doesn't bother me any more than throwing out all salt and water balance knowledge due to results of a study with 10 people. #NephJC
Nephrology Journal Club @NephJC
RT @rheault_m: @NephJC Doesn't bother me any more than throwing out all salt and water balance knowledge due to results of a study with 10 people. #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC Stratification bugs me too, especially with fluid intake--no obvious mechanism #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC perhaps an editorial/reviewer request? #nephjc
Nephrology Journal Club @NephJC
I'm getting ready to move on to the results, any more comments on the methods? #nephjc
Nephrology Journal Club @NephJC
@hswapnil @NephJC I doubt it, most of the interpretation depended on it. #nephjc
Michelle Rheault @rheault_m
@NephJC Methods reinforce how hard it is to collect good 24 hour urine. These were highly trained folk and still 2 couldn't do it. #nephJC
Nephrology Journal Club @NephJC
Topic 2: Results #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Methods: Stats models will become a part of the discussion #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @rheault_m: @NephJC Methods reinforce how hard it is to collect good 24 hour urine. These were highly trained folk and still 2 couldn't do it. #nephJC
Nephrology Journal Club @NephJC
@rheault_m @NephJC astronauts had 4 one hour sessions to train them how to do it too. #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: @rheault_m @NephJC astronauts had 4 one hour sessions to train them how to do it too. #nephjc
Roger Rodby @NephRodby
So you have to be a rocket scientist to collect a 24 hour urine? #nephjc
Nephrology Journal Club @NephJC
@PaulAWelling1 what do you want to say about the stats? Or save it? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@rheault_m @NephJC based on this, likely unblinded! (pg 15/1131) #NephJC https://t.co/T1Hx3SfnJl
J. Brian Byrd Lab @thebyrdlab
RT @NephRodby: So you have to be a rocket scientist to collect a 24 hour urine? #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
RT @NephJC: @PaulAWelling1 what do you want to say about the stats? Or save it? #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC save it #nephjc
Bill Whittier @TWhittier_RUSH
Hi everyone. No COI. here to learn as usual #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
QFT MT @rheault_m: Methods reinforce how hard it is to collect good 24 hour urine. Highly trained folk and still 2 couldn't do it. #nephJC
Nephrology Journal Club @NephJC
RT @hswapnil: @rheault_m @NephJC based on this, likely unblinded! (pg 15/1131) #NephJC https://t.co/T1Hx3SfnJl
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: @rheault_m @NephJC astronauts had 4 one hour sessions to train them how to do it too. #nephjc
Roger Rodby @NephRodby
TWhittier in the house, on parole #nephjc
Nephrology Journal Club @NephJC
Average daily urine sodium fell with the falling dietary sodium intake. Lots of daily variability in Na excretion #NephJC
Nephrology Journal Club @NephJC
They did not see a lot of variability in water intake. #NephJC
Matthew Sparks, MD @Nephro_Sparks
thankful they have wifi for TWittier #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@TWhittier_RUSH Hey Bill! (when are you changing that Avatar!?) #nephjc
Michelle Rheault @rheault_m
@hswapnil @NephJC Way to read the fine print. Thanks! Sounds like a dietitian's nightmare job. #NephJC
Roger Rodby @NephRodby
@hswapnil @TWhittier_RUSH Never! best pic ever #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: Average daily urine sodium fell with the falling dietary sodium intake. Lots of daily variability in Na excretion #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @NephJC: They did not see a lot of variability in water intake. #NephJC
Nephrology Journal Club @NephJC
See how more variability there is in Na than water intake. See it? See it? #NephJC Me neither https://t.co/eKZqnbapTb
Matthew Sparks, MD @Nephro_Sparks
I think we need to reproduce this study at #KidneyWk with #NephJC members providing 24hr urines
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
@hswapnil @rheault_m I've heard Jens comment they pretty much refused to...not such great 'volunteers' #nephjc
Bill Whittier @TWhittier_RUSH
@hswapnil funny how often i get that question. not sure why... #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC but they claim water intake decreased with increasing salt--which, of course, is paradoxical #nephjc
Gates Colbert, MD @DoctorGates
The camel hump reference making water from fat gives me a lot of hope for my adipose collection. #nephjc
Nephrology Journal Club @NephJC
They documented a clear reduction in water intake with increased sodium intake. #NephJC
J. Brian Byrd Lab @thebyrdlab
RT @DrJMLuther: @hswapnil @rheault_m I've heard Jens comment they pretty much refused to...not such great 'volunteers' #nephjc
Matthew Sparks, MD @Nephro_Sparks
oh my RT @DoctorGates: The camel hump reference making water from fat gives me a lot of hope for my adipose collection. #nephjc
Saurabh Jha @RogueRad
@hswapnil @kidney_boy What I want to know. Should I still be taking salt with water if running in the heat & sweating my head off to prevent hyponatremia? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @Nephro_Sparks: I think we need to reproduce this study at #KidneyWk with #NephJC members providing 24hr urines
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC The water decrease is NOT so clear #nephjc
Nephrology Journal Club @NephJC
Water intake fell with increasing sodium intake #NephJC https://t.co/uF9jzDNRKO
J. Brian Byrd Lab @thebyrdlab
RT @PaulAWelling1: @NephJC but they claim water intake decreased with increasing salt--which, of course, is paradoxical #nephjc
Michelle Rheault @rheault_m
RT @PaulAWelling1: @NephJC but they claim water intake decreased with increasing salt--which, of course, is paradoxical #nephjc
Roger Rodby @NephRodby
@NephJC So very nonintuitive, I eat pizza and I am thirsty as hell, but maybe different with acute Na load #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: See how more variability there is in Na than water intake. See it? See it? #NephJC Me neither https://t.co/eKZqnbapTb
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
@hswapnil @rheault_m Matt luther- Vanderbilt nephrologist, Clin Pharm. no Coi but I'll have to review this later- sorry to miss most #NephJC
Michelle Rheault @rheault_m
RT @NephJC: Water intake fell with increasing sodium intake #NephJC https://t.co/uF9jzDNRKO
Arvind Canchi (Conjeevaram)🇮🇳 @arvindcanchi
@NephJC @DoctorGates Morning all. Here in India 42gm of salt seems okay. #nephjc https://t.co/IEsNrwJwIr https://t.co/JMDLMV0fOG
Matthew Sparks, MD @Nephro_Sparks
@NephJC look at that Y axis #nephjc
Matthew Sparks, MD @Nephro_Sparks
@arvindcanchi @NephJC @DoctorGates Hi Arvind #nephjc
Roger Rodby @NephRodby
Acute Na load increases extracellular osmolality and ADH and thirst, don't think that applies here #nephjc
Matthew Sparks, MD @Nephro_Sparks
@DrJMLuther @hswapnil @rheault_m HI James #nephjc
Nephrology Journal Club @NephJC
You just think you are thirsty MT @NephRodby: @So very nonintuitive, I eat pizza and I am thirsty as hell... #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
my bartender swears he sells more drinks when he puts out salty food on the bar #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Water intake fell with increasing sodium intake #NephJC https://t.co/uF9jzDNRKO
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @PaulAWelling1: @NephJC but they claim water intake decreased with increasing salt--which, of course, is paradoxical #nephjc
Ivy Melgarejo @IvyM808
RT @PaulAWelling1: @NephJC but they claim water intake decreased with increasing salt--which, of course, is paradoxical #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: @NephJC So very nonintuitive, I eat pizza and I am thirsty as hell, but maybe different with acute Na load #nephjc
Bill Whittier @TWhittier_RUSH
@NephRodby then if ADH increases, shouldn't urine output fall? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @arvindcanchi: @NephJC @DoctorGates Morning all. Here in India 42gm of salt seems okay. #nephjc https://t.co/IEsNrwJwIr https://t.co/JMDLMV0fOG
Matthew Sparks, MD @Nephro_Sparks
bingo. tons of urinals in bars too RT @PaulAWelling1: my bartender swears he sells more drinks when he puts out salty food on bar #nephjc
Nephrology Journal Club @NephJC
Holy Morton's Salt batman! 42 grams! RT @arvindcanchi: Here in India 42gm of salt seems okay. #nephjc https://t.co/Ms5yqUFo6D #nephjc
Roger Rodby @NephRodby
@TWhittier_RUSH except I DO drink to give water to excrete the Na #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@TWhittier_RUSH @NephRodby if ADH increases, free water clearance decreases #nephjc
İbrahim akdag @iakdag16
RT @edgarvlermamd: How does salt intake affect water intake⁉️ #VisualAbstract by @kidney_boy #NephJC #Nephpearls https://t.co/R3nxSjzBul https://t.co/ooVzSDmwv5
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
I have a little trouble with the water intake studies #nephjc
Nephrology Journal Club @NephJC
@PaulAWelling1 must not be a space bartender #nephjc
محذوف @milardport
RT @NephJC: I'm Joel Topf, @Kidney_Boy and I will be hosting tonight's chat on the world shaking sodium article in JCI #NephJC
محذوف @milardport
RT @NephJC: While we wait for everyone to arrive, please introduce yourselves and reveal any relevent conflicts of interest (COI) #NephJC
Nephrology Journal Club @NephJC
Where do you think they get Miller beer from? RT @Nephro_Sparks: bingo. tons of urinals in bars too #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@PaulAWelling1 me too. But data reported seems to support their conclusion? What am I missing> #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC Image of Star Wars bar #nephjc
محذوف @milardport
RT @NephJC: What would a COI even look like for this study? I work for Morton's Salt? #nephjc
محذوف @milardport
RT @NephJC: No relevent COI, but I wanted to be an astronaut when I was a kid #NephJC
Nephrology Journal Club @NephJC
Urine volume did not track with sodium intake, but did increase with increased sodium excretion. #NephJC
Nephrology Journal Club @NephJC
This is seen with the urine sodium tertiles. #NephJC
Nephrology Journal Club @NephJC
Here is the authors justification for tertles of Na. Look kosher to you? #NephJC https://t.co/GP5M4t7kCY
Nephrology Journal Club @NephJC
Using month long data Na in did equal Na out. So the conservation of mass is still intact. #NephJC
Nephrology Journal Club @NephJC
Na in = Na out, if watch it for a month. #NephJC https://t.co/a8TBqwgT9l
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Look at the middle column, Water intake. Doesn't look very different across groups. Bars are SD, so divide by sq of 10 for SE #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC it looks like Na in = Na out in figure 1 #nephjc
Roger Rodby @NephRodby
@NephJC so we need to do 720 hour urine collections for Na intake study? #nephjc
Nephrology Journal Club @NephJC
yup, this was averaged over a month RT @PaulAWelling1: @NephJC it looks like Na in = Na out in figure 1 #nephjc
Charbel C Khoury @Charbel_Khoury
Mark Zeidel Editorial notes: infusion of hypertonic saline reliably result in ADH release, while thirst is variable #nephjc ref https://t.co/gZ3LWPzhax
Nephrology Journal Club @NephJC
that's what they are saying RT @NephRodby: @NephJC so we need to do 720 hour urine collections for Na intake study? #nephjc
Matthew Sparks, MD @Nephro_Sparks
half of month ok? RT @NephRodby: @NephJC so we need to do 720 hour urine collections for Na intake study? #nephjc
Matthew Sparks, MD @Nephro_Sparks
just do a Urinary Na to Creat ratio on the 720 hour collection #nephjc
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
Over long term but not day to day- we know that single 24hr urine not totally reflect daily Na intake/ this cd explain why #nephjc https://t.co/sKI60792Gp
Nephrology Journal Club @NephJC
The tragic futility of the 24 hour urine #NephJC #CoinToss https://t.co/L5XJUlxGPM
محذوف @milardport
RT @NephJC: The question in the study stems from the observation that Na is rhythmicly stored and released on a weekly and monthly cycle. #NephJC
Roger Rodby @NephRodby
The fact that Na in is not Na out (over a day) is just crazy to me. I figured it would be meal to meal much less several days. #nephjc
Matthew Sparks, MD @Nephro_Sparks
this is me in Vegas RT @NephJC: The tragic futility of the 24 hour urine #NephJC #CoinToss https://t.co/zvRAHNdTde
Nephrology Journal Club @NephJC
To explain the decrease in water intake with higher sodium intake the authors looked to the magic of free water clearance. #NephJC
Nephrology Journal Club @NephJC
The greater the solute load that needed to be cleared the more negative free water clearance became. #NephJC
محذوف @milardport
RT @NephJC: this word, I do not know what it means RT @rheault_m: this word, I do not know what it means RT @rheault_m: @NephJC I think you mean cycle with an "Infradian" rhythm. #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
I'm not buying water intake stats #nephjc
محذوف @milardport
RT @NephJC: Sodium is apparently released when cortisol is at its peak and aldosterone is at its trough #NephJC
Roger Rodby @NephRodby
@PaulAWelling1why? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC should be OK, unless your patient eats dramatically differently every day? #nephjc
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
RT @NephRodby: @NephJC so we need to do 720 hour urine collections for Na intake study? #nephjc
Ivy Melgarejo @IvyM808
RT @NephJC: The greater the solute load that needed to be cleared the more negative free water clearance became. #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: The fact that Na in is not Na out (over a day) is just crazy to me. I figured it would be meal to meal much less several days. #nephjc
Roger Rodby @NephRodby
@hswapnil @NephJC Good point but do we even know that? ' #nephjc
Matthew Sparks, MD @Nephro_Sparks
@PaulAWelling1 would like to understand this as well #nephjc
Nephrology Journal Club @NephJC
@hswapnil @NephJC they showed a lot of variability on fixed diets #nephjc
𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 @DrJMLuther
Or multiple (>=4) 24hr collections to get an average #nephjc https://t.co/RahPAB9hFg
Roger Rodby @NephRodby
@DrJMLuther > 4 collections means no collections #nephjc
Matthew Sparks, MD @Nephro_Sparks
RT @brzoskos:
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Look at figure 1 middle column--intake data are not different. I would use an N= 10 subjects; they used an N ~1600 Pseudo-rep #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: @hswapnil @NephJC they showed a lot of variability on fixed diets #nephjc
Nephrology Journal Club @NephJC
Swapnil this is the problem with a single measurement on a fixed diet. Bouncing around like crazy #NephJC https://t.co/DV9XgtWK7E
محذوف @milardport
RT @NephJC: The simulated Mars missions Mars105 and Mars 520 provided a unique opportunity to do prolonged metabolic balance studies #NephJC
محذوف @milardport
RT @NephJC: You told them it was just Russian Hackers trying to ruin physiology? RT @Nephro_Sparks: You told them it was just Russian Hackers trying to ruin physiology? RT @Nephro_Sparks: Had a patient ask me about this study #nephjc
محذوف @milardport
RT @NephJC: Urine output, water intake and dietary compliance were carefully measured and recorded #NephJC
Matthew Sparks, MD @Nephro_Sparks
@PaulAWelling1 like tele mice BP readings. 6000 BP readings = 1 reading #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Swapnil this is the problem with a single measurement on a fixed diet. Bouncing around like crazy #NephJC https://t.co/DV9XgtWK7E
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @PaulAWelling1: Look at figure 1 middle column--intake data are not different. I would use an N= 10 subjects; they used an N ~1600 Pseudo-rep #nephjc
Nephrology Journal Club @NephJC
The R^2 for this is an unimpressive 0.11, but P<0.001. This relationship could only be detected w/ 1000s of 24-hr urines #NephJC
محذوف @milardport
RT @NephJC: I'm getting ready to move on to the results, any more comments on the methods? #nephjc
Nephrology Journal Club @NephJC
Think of how much data needs to be collected to see a pattern in those seemingly random scatter plots #NephJC https://t.co/beUE7Y7zWT
Nephrology Journal Club @NephJC
Remember a negative FWC means more endogenous water created by the kidney. This happens with concentrated urine. #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC This is were I have a problem with the stratification #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephRodby @NephJC McCarron says so: https://t.co/8bmtx3MrMz (but at population level, based on 24 hour Urine, so who knows!) #NephJC https://t.co/7k8Sqb0lkB
Nephrology Journal Club @NephJC
With lower salt loads, the urine was less concentrated and there was less water generation. #NephJC
Nephrology Journal Club @NephJC
This is what triggered the confusing decrease in water intake with high salt loads, more endogenous water creatin by the kidney #NephJC
Nephrology Journal Club @NephJC
The high salt diet urines had less urea, leading authors to conclude the urea was being concentrated in the medulla #NephJC
Nephrology Journal Club @NephJC
This urea was needed to concentrate the urine and generate the endogenous water creation by the kidney #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Remember a negative FWC means more endogenous water created by the kidney. This happens with concentrated urine. #NephJC
محذوف @milardport
RT @NephJC: They documented a clear reduction in water intake with increased sodium intake. #NephJC
محذوف @milardport
RT @Nephro_Sparks: oh my RT @DoctorGates: oh my RT @DoctorGates: The camel hump reference making water from fat gives me a lot of hope for my adipose collection. #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
We shouldn't be surprised that the FWC decreases with increased salt. Remember ADH? #nephjc
محذوف @milardport
RT @NephJC: Water intake fell with increasing sodium intake #NephJC https://t.co/uF9jzDNRKO
محذوف @milardport
RT @Nephro_Sparks: @NephJC look at that Y axis #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@kidney_boy MT @anniebelch @DrBMK_RD TITZE: Predictions & findings about balancing wobbles in body Na #ERAEDTA17 🇪🇸 #Nephpearls #NephJC https://t.co/w7GrKWdQKd
محذوف @milardport
RT @NephJC: You just think you are thirsty MT @NephRodby: You just think you are thirsty MT @NephRodby: @So very nonintuitive, I eat pizza and I am thirsty as hell... #nephjc
محذوف @milardport
RT @NephJC: Holy Morton's Salt batman! 42 grams! RT @arvindcanchi: Holy Morton's Salt batman! 42 grams! RT @arvindcanchi: Here in India 42gm of salt seems okay. #nephjc https://t.co/Ms5yqUFo6D #nephjc
Nephrology Journal Club @NephJC
The authors suppose cortisol triggers protein catabolism to provide the urea needed to concentrate the urine while excreting NaCl #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
RT @NephJC: The authors suppose cortisol triggers protein catabolism to provide the urea needed to concentrate the urine while excreting NaCl #nephjc
Nephrology Journal Club @NephJC
@PaulAWelling1 but it wouldn't increase ADH if it triggered thirst, which it doesn't? #nephjc
محذوف @milardport
RT @NephJC: Where do you think they get Miller beer from? RT @Nephro_Sparks: Where do you think they get Miller beer from? RT @Nephro_Sparks: bingo. tons of urinals in bars too #nephjc
محذوف @milardport
RT @Nephro_Sparks: bingo. tons of urinals in bars too RT @PaulAWelling1: bingo. tons of urinals in bars too RT @PaulAWelling1: my bartender swears he sells more drinks when he puts out salty food on bar #nephjc
Matthew Sparks, MD @Nephro_Sparks
cortisol is not our friend #nephjc
محذوف @milardport
RT @NephJC: Urine volume did not track with sodium intake, but did increase with increased sodium excretion. #NephJC
محذوف @milardport
RT @NephJC: This is seen with the urine sodium tertiles. #NephJC
محذوف @milardport
RT @NephJC: Here is the authors justification for tertles of Na. Look kosher to you? #NephJC https://t.co/GP5M4t7kCY
Roger Rodby @NephRodby
@NephJC wow, what a thought, but seems way too complicated #nephjc
Nephrology Journal Club @NephJC
trying to wrap cortisol in to sodium and water balance is when my brain says STOP, that's ALDOS job! #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
For some reason they focus on cortisol (second paper), rather than the well known effects of ADH on urea, AQP2, urine concentration #nephjc
محذوف @milardport
RT @NephJC: Using month long data Na in did equal Na out. So the conservation of mass is still intact. #NephJC
Nephrology Journal Club @NephJC
RT @PaulAWelling1: For some reason they focus on cortisol (second paper), rather than the well known effects of ADH on urea, AQP2, urine concentration #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: This is what triggered the confusing decrease in water intake with high salt loads, more endogenous water creatin by the kidney #NephJC
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Sodium is the job of aldosterine, water ADH @NephJC #nephjc
محذوف @milardport
RT @NephJC: that's what they are saying RT @NephRodby: that's what they are saying RT @NephRodby: @NephJC so we need to do 720 hour urine collections for Na intake study? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: The authors suppose cortisol triggers protein catabolism to provide the urea needed to concentrate the urine while excreting NaCl #nephjc
Matthew Sparks, MD @Nephro_Sparks
dogma RT @PaulAWelling1: Sodium is the job of aldosterine, water ADH @NephJC #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @Nephro_Sparks: dogma RT @PaulAWelling1: dogma RT @PaulAWelling1: Sodium is the job of aldosterine, water ADH @NephJC #nephjc
محذوف @milardport
RT @Nephro_Sparks: this is me in Vegas RT @NephJC: this is me in Vegas RT @NephJC: The tragic futility of the 24 hour urine #NephJC #CoinToss https://t.co/zvRAHNdTde
محذوف @milardport
RT @NephJC: The tragic futility of the 24 hour urine #NephJC #CoinToss https://t.co/L5XJUlxGPM
محذوف @milardport
RT @NephJC: To explain the decrease in water intake with higher sodium intake the authors looked to the magic of free water clearance. #NephJC
محذوف @milardport
RT @NephJC: The greater the solute load that needed to be cleared the more negative free water clearance became. #NephJC
Matthew Sparks, MD @Nephro_Sparks
seems like we can repeat these in mice/rats and do some interventional stuff (or maybe that is in supplemental) #nephjc
Rob Bruno @drrobbruno
RT @NephJC: Think of how much data needs to be collected to see a pattern in those seemingly random scatter plots #NephJC https://t.co/beUE7Y7zWT
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
@NephJC Not sure what you mean by "it wouldn't increase ADH if it triggered thirst, which it doesn't? " #nephjc
Roger Rodby @NephRodby
Not to trivialize this at all, but can anyone give me clinical significance except not collecting 24 hr U Na? #nephjc
Nephrology Journal Club @NephJC
@Nephro_Sparks so there is a companion publication with mouse data and some interventional manipulation #nephjc
محذوف @milardport
RT @NephJC: Swapnil this is the problem with a single measurement on a fixed diet. Bouncing around like crazy #NephJC https://t.co/DV9XgtWK7E
Rob Bruno @drrobbruno
RT @NephJC: The tragic futility of the 24 hour urine #NephJC #CoinToss https://t.co/L5XJUlxGPM
محذوف @milardport
RT @NephJC: Think of how much data needs to be collected to see a pattern in those seemingly random scatter plots #NephJC https://t.co/beUE7Y7zWT
محذوف @milardport
RT @NephJC: This urea was needed to concentrate the urine and generate the endogenous water creation by the kidney #NephJC
محذوف @milardport
RT @NephJC: The high salt diet urines had less urea, leading authors to conclude the urea was being concentrated in the medulla #NephJC
Matthew Sparks, MD @Nephro_Sparks
figured (sorry) RT @NephJC: so there is a companion publication with mouse data and some interventional manipulation #nephjc
محذوف @milardport
RT @NephJC: The authors suppose cortisol triggers protein catabolism to provide the urea needed to concentrate the urine while excreting NaCl #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
The mouse study shows fluid intake increased with increases dietary salt, unless mice were give salt water instead of tap water #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@PaulAWelling1 @NephJC yeah: high sodium intake-> increased osmolality -> more ADH (& thirst) at least transiently? #nephjc
Nephrology Journal Club @NephJC
@NephRodby I think the biggest take away is we have built huge knowledge edifices on the 24 hour Urine Na = 24 hour dietary Na #nephjc
Nephrology Journal Club @NephJC
@NephJC @NephRodby If that is false, all of the INTERSALT study and so many observations of Na and mortality fail. #nephjc
Roger Rodby @NephRodby
@NephJC "huge knowledge edifices" who talks like that? #nephjc
Matthew Sparks, MD @Nephro_Sparks
mentioned that on rounds today RT @NephRodby: @NephJC "huge knowledge edifices" who talks like that? #nephjc
Roger Rodby @NephRodby
@NephJC @NephJC I know, throws a real wrench in so many studies? #nephjc
Nephrology Journal Club @NephJC
@NephRodby @NephJC It's all just castles made of sand https://t.co/qADeoOcdvU #nephjc
Michelle Rheault @rheault_m
@Nephro_Sparks Any reason to think results would be different in women? Are there sex differences in sodium balance/aldo effect? #NephJC
Matthew Sparks, MD @Nephro_Sparks
@rheault_m my guess is YES... a birdy told me to watch the journals for a big paper coming soon #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC very very speculative...#NephJC (I am clinging to the dogma...)
Nephrology Journal Club @NephJC
Hey, another hour has slipped away like grains of salt in the wind. Thanks for coming and wrapping your brain around this study #nephjc
Nephrology Journal Club @NephJC
I'm going for a run. #nephjc
Matthew Sparks, MD @Nephro_Sparks
thanks @kidney_boy #nephjc
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
There is physiological basis for no change in water intake with increased salt. The small increase in ECFV causes AngII to decrease #nephjc
Matthew Sparks, MD @Nephro_Sparks
fantastic chat. interesting study. got us all thinking sodium #nephjc
Matthew Sparks, MD @Nephro_Sparks
thanks @PaulAWelling1 for joining and sharing your wisdom #nephjc
Roger Rodby @NephRodby
@NephJC " Like the sands through the hourglass, so are the days of our lives" #nephjc
Charbel C Khoury @Charbel_Khoury
??? #NephJC https://t.co/IpVYKMoTL0
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Hey, another hour has slipped away like grains of salt in the wind. Thanks for coming and wrapping your brain around this study #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @PaulAWelling1: There is physiological basis for no change in water intake with increased salt. The small increase in ECFV causes AngII to decrease #nephjc
J. Brian Byrd Lab @thebyrdlab
RT @Nephro_Sparks: fantastic chat. interesting study. got us all thinking sodium #nephjc
Arvind Canchi (Conjeevaram)🇮🇳 @arvindcanchi
@NephJC This is all very confusing. My brain in pickled. #NephJC
Matthew Sparks, MD @Nephro_Sparks
The numbers: 409 Tweets. 62 Participants. More #NephJC 📊 here https://t.co/4ftgkHjcRM via @symplur
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
wow its 10:03 already (still on pg 17/1131!) thanks everyone - esp @Paulwelling1 for coming. And great job @Kidney_boy #nephjc
Roger Rodby @NephRodby
@Twhittier_Rush, back to his cellblock. #nephjc
Matthew Sparks, MD @Nephro_Sparks
is it a high or low sodium day RT @NephRodby: @Twhittier_Rush, back to his cellblock. #nephjc
Nephrology Journal Club @NephJC
More than I thought: 409 Tweets. 62 Participants. June 5th 2017. More #NephJC 📊 here https://t.co/GrmCNbVzaK via @symplur
Paul A Welling,@PAWellingMD@med-mastodon.com @PAWellingMD
Thanks @kidney_boy; this was fun 1hr goes by quickly #nephjc
Franklin Loachamin @FranLoachamin
RT @edgarvlermamd: How does salt intake affect water intake⁉️ #VisualAbstract by @kidney_boy #NephJC #Nephpearls https://t.co/R3nxSjzBul https://t.co/ooVzSDmwv5
Nephrology Journal Club @NephJC
@PaulAWelling1 you really made the chat. We depend on our community to provide expertise and you delivered the mail. Thanks #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
there seems to be some heterogeneity: 11, 15, 53: body weight went up with lower sodium intakes...(on pg 19/1131 - long way to go!) #NephJC https://t.co/4S5hnnVhEq
Roger Rodby @NephRodby
#nephJC https://t.co/Rnr30a6D4J
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: @PaulAWelling1 you really made the chat. We depend on our community to provide expertise and you delivered the mail. Thanks #nephjc
Joel M. Topf, MD FACP @kidney_boy
RT @edgarvlermamd: @kidney_boy MT @anniebelch @DrBMK_RD TITZE: @kidney_boy MT @anniebelch @DrBMK_RD TITZE: Predictions & findings about balancing wobbles in body Na #ERAEDTA17 🇪🇸 #Nephpearls #NephJC https://t.co/w7GrKWdQKd
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Ok that supplement pgs 28 - 1131 is just code & output. 1-27 is what you should be reading, Fascinating https://t.co/hhUX8MYXHI #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
you know what: why should there be a physiological circadian 24 hour cycle for this? Maybe they are right...(talking to myself) #nephjc
Thahir @docthahir
RT @edgarvlermamd: Renal Physiology 101: Renal Physiology 101: Regulators of renal Na excretion #Nephpearls #NephJC 👉🏼 https://t.co/qaIE4wl9ac https://t.co/nfOiOODGSL
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@PaulAWelling1 @NephJC They do mention ADH in limitations: #NephJC https://t.co/RKddk0wp33
Matthew Sparks, MD @Nephro_Sparks
RT @hswapnil: @PaulAWelling1 @NephJC They do mention ADH in limitations: @PaulAWelling1 @NephJC They do mention ADH in limitations: #NephJC https://t.co/RKddk0wp33
Abraham E. Gracia R. @Abraham_RMI
RT @edgarvlermamd: Renal Physiology 101: Renal Physiology 101: Regulators of renal Na excretion #Nephpearls #NephJC 👉🏼 https://t.co/qaIE4wl9ac https://t.co/nfOiOODGSL
Abraham E. Gracia R. @Abraham_RMI
RT @edgarvlermamd: @Nephro_Sparks Did you say gravity 🚀 ⁉️ #NephJC https://t.co/sVznn74dR2
Abraham E. Gracia R. @Abraham_RMI
RT @edgarvlermamd: How does salt intake affect water intake⁉️ #VisualAbstract by @kidney_boy #NephJC #Nephpearls https://t.co/R3nxSjzBul https://t.co/ooVzSDmwv5
Helbert Rondon, MD, MS, FACP, FASN, FNKF @NephroMD
RT @rheault_m: @NephJC Doesn't bother me any more than throwing out all salt and water balance knowledge due to results of a study with 10 people. #NephJC
#NephJC content from Twitter.