#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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See #NephJC Influencers/Analytics.

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jesse macs @lasvegaskidney
RT @edgarvlermamd: MT @arvindcanchi @ISNeducation ANCA Vasculitis: MT @arvindcanchi @ISNeducation ANCA Vasculitis: Factors increasing risk of relapse #Nephpearls #NephJC #WCN2017 🇲🇽 https://t.co/xOF06Lcmdu
jesse macs @lasvegaskidney
RT @edgarvlermamd: Potential therapeutic targets in ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/CCru5MgPfu https://t.co/gdPYNXFu6H
Dr. Miguel A. Cota:. @macotav
RT @ISNeducation: @edgarvlermamd @arvindcanchi This might be of interest from @macotav https://t.co/cv6m1TCwmg #nephJC #Nephpearls
Ana Maria Matias @AMCMA6
RT @GlomCon1: Tonigh #NephJC will discuss the study of C5a receptor inhibitor in ANCA-associated vasculitis. We look forward to a glombastic discussion! https://t.co/SKZJf7adSv
Ana Maria Matias @AMCMA6
RT @edgarvlermamd: Pathogenesis of ANCA Vasculitis #NephJC 👉🏼 https://t.co/l2DB0cOldd https://t.co/rBGFKFScHw
Ana Maria Matias @AMCMA6
RT @edgarvlermamd: MT @arvindcanchi @ISNeducation ANCA Vasculitis: MT @arvindcanchi @ISNeducation ANCA Vasculitis: Factors increasing risk of relapse #Nephpearls #NephJC #WCN2017 🇲🇽 https://t.co/xOF06Lcmdu
manuel macia heras @mmacia25
RT @NephJC: Less than 60 minutes to tonight's #NephJC Not too late to read the article: https://t.co/XQIiqDrL5j Or summary: https://t.co/ebwCRF1adF
Ana Maria Matias @AMCMA6
RT @ISNeducation: @edgarvlermamd @arvindcanchi This might be of interest from @macotav https://t.co/cv6m1TCwmg #nephJC #Nephpearls
Ana Maria Matias @AMCMA6
RT @NephRodby: Anything that spares or avoids steroids has Holy Grail potential #NephJC
Ana Maria Matias @AMCMA6
RT @NephRodby: Even though we save a life every time we dialyze, nothing is like bringing someone back from the dead from vasculitis #NephJC
Sanjeev Nair @Nair_Sanj
@KidneyCathy I am sure 1 of them did given I am the father. Not very sure about his mother though. #nephjc in the morning didn't exactly endear me 2 her😂
Fede P.S. @Sensingcrackest
RT @edgarvlermamd: @NephRodby Potential therapeutic targets in ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/CCru5MyqE4 https://t.co/mPOpKDaM2y
Trinity Kidneys @THKC1
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
Dr.Ling @wenxinv
RT @edgarvlermamd: Pathogenesis of ANCA Vasculitis #NephJC 👉🏼 https://t.co/l2DB0cOldd https://t.co/rBGFKFScHw
Ernesto LopezAlmaraz @kidney_doctor
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
V. Ocampo D @vod_md
RT @edgarvlermamd: Pathogenesis of ANCA Vasculitis #NephJC 👉🏼 https://t.co/l2DB0cOldd https://t.co/rBGFKFScHw
UmaraniMK @umaranigubbi
RT @JMGardnerMD: RT @BethBraunhut: RT @BethBraunhut: Gorgeous example of membranous nephropathy. Looks at those spikes! #pathology #pathArt #nephJC https://t.co/xAUlZfEUR4
Luis Raul López @luisraulmt
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
Anace Pastor ✨️ Renalis 🌷@Anace710 @anace710
RT @edgarvlermamd: Pathogenesis of ANCA Vasculitis #NephJC 👉🏼 https://t.co/l2DB0cOldd https://t.co/rBGFKFScHw
Anace Pastor ✨️ Renalis 🌷@Anace710 @anace710
RT @GlomCon1: Tonigh #NephJC will discuss the study of C5a receptor inhibitor in ANCA-associated vasculitis. We look forward to a glombastic discussion! https://t.co/SKZJf7adSv
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @DearbhlaKelly4:
Ester Sifuentes @T_Tsita
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
Sanjeev Nair @Nair_Sanj
RT @ISNeducation: @edgarvlermamd @arvindcanchi This might be of interest from @macotav https://t.co/cv6m1TCwmg #nephJC #Nephpearls
Ester Sifuentes @T_Tsita
RT @NephJC: Can a rheumatologist comment on the suitability of the Birmingham score for acute change? #nephJC #RheumJC
Ester Sifuentes @T_Tsita
RT @edgarvlermamd: C-ANCA Chocolate chip cookie 🍪 P-ANCA Popcorn 🍿 Credits: @ph_nachman #Nephpearls #NephJC https://t.co/f9f5tp1Vgs
Manan Doshi @manan_doshi
RT @ISNeducation: @edgarvlermamd @arvindcanchi This might be of interest from @macotav https://t.co/cv6m1TCwmg #nephJC #Nephpearls
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
@VasculitisIA @VasculitisUK @vascuk @VasculitisFound @UKvasculiti : Here is the #storify from last night's #nephJC chat #vasculitis https://t.co/GF6RFOiJOA
Pediatric Critical Care Medicine @PedCritCareMed
The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Sapna Kudchadkar, MD, PhD @SapnaKmd
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Alice Ackerman, MD, @CloseToHomeMD
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
Thanks @ASNKidney for sharing the information about the #AskASN chat on #Kidneyweek17 I'll be there #nephJC #KidneyDisease https://t.co/WQtIjcSR4K
Susan K 🇺🇦☮️ @bp1458
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Johns Hopkins Pediatric Critical Care Medicine @HopkinsPedsCCM
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
The Johns Hopkins PICU Up! Program @PICU_Up
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Syed Shahrul Naz @drshahrul80
RT @edgarvlermamd: C-ANCA Chocolate chip cookie 🍪 P-ANCA Popcorn 🍿 Credits: @ph_nachman #Nephpearls #NephJC https://t.co/f9f5tp1Vgs
Syed Shahrul Naz @drshahrul80
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
Syed Shahrul Naz @drshahrul80
RT @edgarvlermamd: Renal Vasculitis #Nephpearls #NephJC https://t.co/M8K8c5qPBo
Syed Shahrul Naz @drshahrul80
RT @edgarvlermamd: Potential therapeutic targets in ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/CCru5MgPfu https://t.co/gdPYNXFu6H
manuel macia heras @mmacia25
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
Syed Shahrul Naz @drshahrul80
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Ana Maria Matias @AMCMA6
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
Ana Maria Matias @AMCMA6
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
#KidneyDisease #RareDisease #esrd #vasculitis https://t.co/6Heu7NVHbP
Joel M. Topf, MD FACP @kidney_boy
Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
Arvind Canchi (Conjeevaram)🇮🇳 @arvindcanchi
RT @kidney_boy: Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
NBLU: Renal Leaders @NBLUniv
Great example of a #visualabstract!What font is that on the top line? https://t.co/ikxb83GMsH
Raj Mehta @raj_mehta
RT @kidney_boy: Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
Sibel Gokcay Bek @sibgokcay
RT @kidney_boy: Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
Fadel Alrowaie @fadelrowaie
RT @edgarvlermamd: C-ANCA Chocolate chip cookie 🍪 P-ANCA Popcorn 🍿 Credits: @ph_nachman #Nephpearls #NephJC https://t.co/f9f5tp1Vgs
Haneen Al.Maghrabi @Haneen_Maghrabi
RT @edgarvlermamd: C-ANCA Chocolate chip cookie 🍪 P-ANCA Popcorn 🍿 Credits: @ph_nachman #Nephpearls #NephJC https://t.co/f9f5tp1Vgs
Fadel Alrowaie @fadelrowaie
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
Fadel Alrowaie @fadelrowaie
RT @edgarvlermamd: Renal Vasculitis #Nephpearls #NephJC https://t.co/M8K8c5qPBo
Amer Mansour @am_altamimi
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
Andrew M. Ibrahim MD, MSc (He/Him) @AndrewMIbrahim
RT @kidney_boy: Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
UVA PICU @UVA_PICU
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Mana @manasigh
RT @edgarvlermamd: Potential therapeutic targets in ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/CCru5MgPfu https://t.co/gdPYNXFu6H
Brian Walsh PhD RRT @BrianKWalsh
RT @PedCritCareMed: The August @PedCritCareMed is out today, with FREE Feature Articles on their way! https://t.co/tS4CbqgIHl #sepsis #nephJC #airway #PedsICU https://t.co/7fWpmVVw0x
Rob Peel🏳️‍🌈💙🇬🇧🏴󠁧󠁢󠁳󠁣󠁴󠁿 @rabpeel
On holiday , a shame because @NHSHRenal is part of a trial with it https://t.co/95eWwAjSO1
Mo Alzubaidi @NephrosisMo
RT @kidney_boy: Beta #VisualAbstract for tonight's (and last night's) #NephJC Avacopan for ANCA Associated Vasculitis, a phase 2 trial https://t.co/cgfVSqqp4I
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
@KidneyPatients @RSNhope @PKDFoundation @KidneyResInst @kidneystories @GKH_org Hope you can join the conversation! #askasn #NephJC https://t.co/vp0A3rfXUa
Nephrology Journal Club @NephJC
T-90 minutes to #NephJC on Avacopan as a steroid alternative in ANCA vasculitis! All welcome!
Ana Maria Matias @AMCMA6
RT @manirath: @NephJC Ritux has come in big way. Now the first line of tx #NephJC
Jim Myers @kidneystories
RT @gratefull080504: @KidneyPatients @RSNhope @PKDFoundation @KidneyResInst @kidneystories @GKH_org Hope you can join the conversation! #askasn #NephJC https://t.co/vp0A3rfXUa
Nephrology Journal Club @NephJC
Welcome to #NephJC tonight! I @DearbhlaKelly4 will be your host. Please introduce yourself and declare any COI.
Nephrology Journal Club @NephJC
Tonight we are discussing Avacopan in ANCA-associated vasculitis. You can read the paper at https://t.co/XQIiqDrL5j #NephJC
Nephrology Journal Club @NephJC
Or read or @toates_19 wonderful summary here https://t.co/ebwCRF1adF #NephJC
Nephrology Journal Club @NephJC
We recommend using https://t.co/rFoH4MVMzu or TChat.io to follow the #nephjc chat. See a how to guide here: http//www.nephjc.com/how-to/
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Swapnil Hiremath from @OttawaHospital Lurking, but trying to make up for missing last night #NephJC https://t.co/cYKKd6X2Ru
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Or read or @toates_19 wonderful summary here https://t.co/ebwCRF1adF #NephJC
Nephrology Journal Club @NephJC
Let's kick off! T0: Steroids are the driving force for morbidity/mortality now in AAV. Who agrees? #NephJC
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @NephJC: Or read or @toates_19 wonderful summary here https://t.co/ebwCRF1adF #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@vascuk thanks for joining - and contributing to the @NephJC commentary! https://t.co/qyGAq881C8 @DearbhlaKelly4 #nephjc
Nephrology Journal Club @NephJC
RT @hswapnil: @vascuk thanks for joining - and contributing to the @NephJC commentary! https://t.co/qyGAq881C8 @DearbhlaKelly4 #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
T0: not sure. AAV pretty bad and nasty by itself (esp the renal cases seen by us). Steroids bad, AAV badder? #nephjc
Nephrology Journal Club @NephJC
T0: the greatest threat to patients with AAV in their first year is adverse tx events #nephjc https://t.co/45gqAenklM
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @DrMattGB: T0:
Nephrology Journal Club @NephJC
RT @hswapnil: T0: T0: not sure. AAV pretty bad and nasty by itself (esp the renal cases seen by us). Steroids bad, AAV badder? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @vascuk:
Nephrology Journal Club @NephJC
T0: From EUVAS trials, 41% had hypertension, 38% osteoporosis, 28% diabetes mellitus and 25% had cataracts. #NephJC https://t.co/wNL6QYcxEJ
Nephrology Journal Club @NephJC
RT @DrMattGB: T0:
Nephrology Journal Club @NephJC
RT @vascuk:
Nephrology Journal Club @NephJC
T0: Avacopan -small-molecule C5aR antagonist that blocks the effects of C5a, reducing neutrophil activation, accumulation & adhesion #NephJC
Nathaniel Reisinger @nephrothaniel
Nathaniel Reisinger. Nephrologist and clinical ultrasound fellow @PennKidney no pertinent COI #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @caioqualunque: T0:
Nephrology Journal Club @NephJC
T0: Complement - the hipster bruncher of the immunology world at the moment! #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: T0: T0: Avacopan -small-molecule C5aR antagonist that blocks the effects of C5a, reducing neutrophil activation, accumulation & adhesion #NephJC
Nephrology Journal Club @NephJC
T1: Moving on to methods - Randomised, phase II, double-blind, placebo-controlled, trial running from 2011-2016 #NephJC
Nephrology Journal Club @NephJC
T1: Interesting study design as exemplified in @kidney_boy visual abstract. Tx for just 12 wks #NephJC https://t.co/rLdiakG1gr
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: T1: T1: Interesting study design as exemplified in @kidney_boy visual abstract. Tx for just 12 wks #NephJC https://t.co/rLdiakG1gr
Nephrology Journal Club @NephJC
RT @vascuk:
Nephrology Journal Club @NephJC
@vascuk True but they seem to not be enough to prevent relapse? #NephJC
Joel M. Topf, MD FACP @kidney_boy
@caioqualunque Help me out why is that both misleading and true? It was striking. I came this close to tweeting yesterday. #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@louise_oni Hey Louise, thanks for joining in! Welcome to #NephJC
Nephrology Journal Club @NephJC
T1: What isn't clear from me from the methods is whether patients got methylprednisolone during induction with cyclophosphamide? #NephJC
Nephrology Journal Club @NephJC
T1: Primary endpoint chosen was a decrease in Birmingham Vasculitis Activity Score of 50% or more – any issues with this? #NephJC
Joel M. Topf, MD FACP @kidney_boy
Searched the whole document and the word methylprednisone wasn't used. #nephjc
Nephrology Journal Club @NephJC
RT @caioqualunque: T0:
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@kidney_boy @caioqualunque I am w/ Francesco. Citation 2: https://t.co/p8A7ImQ4qu true: infection > vascultitis misleading: would have likely died without Rx #NephJC https://t.co/hMTbiQnDED
محذوف @milardport
RT @NephJC: T-90 minutes to #NephJC on Avacopan as a steroid alternative in ANCA vasculitis! All welcome!
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Methodology set up for one outcome - but results extrapolated to another. Thx @poyanmehr #nephjc https://t.co/oeSxkJWyJp
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @vascuk:
Nephrology Journal Club @NephJC
A single dose of MP can have lasting effects on immunity. It would be important to define if there was truly a steroid free arm #NephJC https://t.co/q6vh8Xka7g
Nephrology Journal Club @NephJC
RT @hswapnil: @kidney_boy @caioqualunque I am w/ Francesco. Citation 2: @kidney_boy @caioqualunque I am w/ Francesco. Citation 2: https://t.co/p8A7ImQ4qu true: infection > vascultitis misleading: would have likely died without Rx #NephJC https://t.co/hMTbiQnDED
Nephrology Journal Club @NephJC
RT @poyanmehr: @NephJC @kidney_boy that is where the confusion comes in. clearly not powered & designed for what we would like to see #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @alehkir: @caioqualunque #nephJC misleading b/c in spite of treatment-associated morbidity/mortality hard to argue:
Nephrology Journal Club @NephJC
RT @DrMattGB:
Nephrology Journal Club @NephJC
T1: If the study had used a pre-specified BVAS scores of 0 instead of relative change, would this have been more compelling? #NephJC
Nephrology Journal Club @NephJC
T1: Analysis was intention to treat and based on non-inferiority #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC BVAS quite well accepted/validated (though I am w/ @DrMattGB on not being an expert on this; research tool > clinical use) #NephJC https://t.co/kcoBYO5eEk
Nephrology Journal Club @NephJC
RT @caioqualunque: T1:
Nephrology Journal Club @NephJC
RT @hswapnil: @NephJC BVAS quite well accepted/validated (though I am w/ @DrMattGB on not being an expert on this; research tool > clinical use) #NephJC https://t.co/kcoBYO5eEk
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC Ah, 20% non-inferiority (same as RAVE ). Time for me to roll out the non-inferiority must read https://t.co/uEBHVQoHIB #nephjc https://t.co/8Ppq2l7e1S
Nephrology Journal Club @NephJC
T2: Here is @toates_19 summary of efficacy findings. 'Tx response' seen in high proportion in all 3 grips #nephjc https://t.co/KaaTqs8Eqm
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
#NephJC https://t.co/KcvQTJ6AO2
Nephrology Journal Club @NephJC
RT @hswapnil: @NephJC Ah, 20% non-inferiority (same as RAVE ). Time for me to roll out the non-inferiority must read https://t.co/uEBHVQoHIB #nephjc https://t.co/8Ppq2l7e1S
Nephrology Journal Club @NephJC
T2: Mostly new diagnoses though some relapses with equal split MPO and PR3 #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: T2: T2: Here is @toates_19 summary of efficacy findings. 'Tx response' seen in high proportion in all 3 grips #nephjc https://t.co/KaaTqs8Eqm
Vasculitis Stichting @Vasculitis_NL
RT @caioqualunque: T0:
Nephrology Journal Club @NephJC
T2: only key diff between groups was that placebo + pred group had worse renal disease at baseline but Ava renally protective? #NephJC
Nephrology Journal Club @NephJC
Yes it's reassuring for PR3 patients albeit too short a trial to compare relapse rates #NephJC https://t.co/kz8j9CdNxE
Nephrology Journal Club @NephJC
T2: Seems to be safe. Adverse events were similar across all groups, with 17% (4/23) control patients and 25% (11/44) ava patients #NephJC
Nephrology Journal Club @NephJC
T2: Fewer side effects related to GC use were seen in patients on Ava (34% v 65%). Mainly fewer psych disorders and new DM. #NephJC
Gates Colbert, MD @DoctorGates
Dallas based Nephrologist. Lurking today and participating last night. #NephJC
Nephrology Journal Club @NephJC
RT @caioqualunque: T0:
Nephrology Journal Club @NephJC
Yes RITUXVAS was sponsored by La Roche I believe #NephJC https://t.co/4ilWn4B4gb
Nephrology Journal Club @NephJC
RT @caioqualunque: T2: inclusion criteria:
Nephrology Journal Club @NephJC
RT @alehkir:
Nephrology Journal Club @NephJC
T2: Interestingly, more lymphopenia with avacopan compared with control/steroid group. Any explanations for this? #NephJC
Nephrology Journal Club @NephJC
Really good point Fra! I didn't see that in study protocol? #nephJC https://t.co/BaDylLkCyH
Nephrology Journal Club @NephJC
@Edwinwong00 will definitely know the answer to this! #NephJC
Nephrology Journal Club @NephJC
RT @alehkir: @caioqualunque we're participating in the f/u study:
Nephrology Journal Club @NephJC
T3: So is this a win for Avacopan to replace high dose steroids? Chemocentryx certainly seem to think so with phase 3 studies #NephJC
Nephrology Journal Club @NephJC
T3: Definitely some valid statistical concerns as outlined by @toates_19 on their choice of primary outcome for a short study period #NephJC
Nephrology Journal Club @NephJC
Don't think we know yet #NephJC https://t.co/ELYbgWxEtH
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @alehkir:
Nephrology Journal Club @NephJC
T3:It will be interesting to see longterm data given that previous concerns about steroid withdrawal were based on withdrawal < 1yr #NephJC
Nephrology Journal Club @NephJC
https://t.co/qhM7JSPLev #NephJC
Nephrology Journal Club @NephJC
RT @DrMattGB:
Nephrology Journal Club @NephJC
RT @Errantnephron:
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
T3: not a perfect study. But rare/orphan dz, kudos to sponsor + researchers. Just happy new molecules being tested! #NephForward #nephjc
Nephrology Journal Club @NephJC
RT @vascuk:
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Yes! QFT MT @caioqualunque: We all want avacopan to win its race over steroids. #nephjc
Nephrology Journal Club @NephJC
RT @alehkir:
Nephrology Journal Club @NephJC
Time to wrap up I think! Thanks everyone for a really interesting discussion! #NephJC
TOUNSI @TUNISIAMOUNTAIN
Tunisian Journal of Medicine est sorti de presse! https://t.co/nGssMCYvCX Les unes d'aujourd'hui via @EMJRheum #arthritis #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @caioqualunque:
Ed @Rx_Ed
@NephJC Vaccination with avacopan likely not required because it's a receptor blocker. Eculizumab is a complement cleavage inhibitor. #NephJC
Joel M. Topf, MD FACP @kidney_boy
Solid #NephJC w/ 633 Tweets 125 Participants btw 2 Chats. Thanks @KidneyCathy & @DearbhlaKelly4. 📊 https://t.co/NMvBBK8cWS via @symplur
Nephrology Journal Club @NephJC
RT @Rx_Ed: @NephJC Vaccination with avacopan likely not required because it's a receptor blocker. Eculizumab is a complement cleavage inhibitor. #NephJC
Krishna Penmatsa @krishnadoctor1
RT @caioqualunque:
Poyan Mehr @poyanmehr
RT @NephJC: Methodology set up for one outcome - but results extrapolated to another. Thx @poyanmehr #nephjc https://t.co/oeSxkJWyJp
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: MT @arvindcanchi @ISNeducation ANCA Vasculitis: MT @arvindcanchi @ISNeducation ANCA Vasculitis: Factors increasing risk of relapse #Nephpearls #NephJC #WCN2017 🇲🇽 https://t.co/xOF06Lcmdu
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: ANCA Vasculitis: ANCA Vasculitis: Predictors of treatment relapse/ resistance #Nephpearls #NephJC https://t.co/sBKk4ek8uS
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Pathogenetic model highlighting differences between PR3-ANCA vs MPO-ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/3kSVh4n1nT
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Birmingham Vasculitis Activity Score (BVAS) #Nephpearls #NephJC https://t.co/bYPpe3xyt2
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Flow diagram for treatment of ANCA Vasculitis ca. 2015 #Nephpearls #NephJC 👉🏼 https://t.co/ERXMI3qFB8 https://t.co/qmnoDphueD
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Renal Vasculitis #Nephpearls #NephJC https://t.co/M8K8c5qPBo
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Potential therapeutic targets in ANCA Vasculitis #Nephpearls #NephJC 👉🏼 https://t.co/CCru5MgPfu https://t.co/gdPYNXFu6H
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @edgarvlermamd: Pathogenesis of ANCA Vasculitis #NephJC 👉🏼 https://t.co/l2DB0cOldd https://t.co/rBGFKFScHw
Alex Meraz @NephroGuy
RT @NephJC: T1: T1: Interesting study design as exemplified in @kidney_boy visual abstract. Tx for just 12 wks #NephJC https://t.co/rLdiakG1gr
Manish Rathi @manirath
RT @hswapnil: T0: T0: not sure. AAV pretty bad and nasty by itself (esp the renal cases seen by us). Steroids bad, AAV badder? #nephjc
Dr Mukesh Rulaniya @RulaniyaDr
RT @caioqualunque:
Dr Mukesh Rulaniya @RulaniyaDr
RT @caioqualunque:
#NephJC content from Twitter.