#LCSM Transcript

Healthcare social media transcript of the #LCSM hashtag.
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See #LCSM Influencers/Analytics.

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Fred Gray @fcgiii
I see you #lcsm
NCI Cancer Stats @NCICancerStats
Every year, ~7,330 lung cancer deaths occur among adult nonsmokers in the United States as a result of #secondhandsmoke. Check out NCI Map Stories for more info: https://t.co/1GvSpfGmUy #LCSM https://t.co/vh3MkX0osA
Janet Freeman-Daily @JFreemanDaily
Welcome to the first #LCSM Chat of 2019! We’ve shifted to monthly chats this year. Tonight we’re hosting a collaborative chat across all cancer hashtag communities #hcsm #bcsm #btsm #gyncsm #mmsm #ayacsm, etc. To participate, include #LCSM in all your tweets.
joey steward @jsteward2930
RT @NCICancerStats: Every year, ~7,330 lung cancer deaths occur among adult nonsmokers in the United States as a result of #secondhandsmoke
Janet Freeman-Daily @JFreemanDaily
@SunshineKK68 Yep, we're on! Here we go! #LCSM
Janet Freeman-Daily @JFreemanDaily
Tonight’s chat is titled “Immunotherapy: What patients need to know.” More info at https://t.co/yzwKSTFWfl #LCSM
Timothy Craig Allen @TimAllenMDJD
Tim here. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Welcome to the first #LCSM Chat of 2019! We’ve shifted to monthly chats this year. Tonight we’re hosting a collaborative…
Faces of Lung Cancer @LungCancerFaces
RT @JFreemanDaily: Welcome to the first #LCSM Chat of 2019! We’ve shifted to monthly chats this year. Tonight we’re hosting a collaborative…
Janet Freeman-Daily @JFreemanDaily
We'll get started in a few minutes -- please take a moment to introduce yourselves #LCSM
Faces of Lung Cancer @LungCancerFaces
RT @JFreemanDaily: Tonight’s chat is titled “Immunotherapy: What patients need to know.” More info at https://t.co/yzwKSTFWfl #LCSM
Christine Qiong Wu @wi_qiong
I'm here. #lcsm
Kim Moran-MacIntosh 🇨🇦 @Kamacintosh
I'm here #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: We'll get started in a few minutes -- please take a moment to introduce yourselves #LCSM
#LCSM Chat @lcsmchat
@wi_qiong Welcome Christine! #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: Tonight’s chat is titled “Immunotherapy: What patients need to know.” More info at https://t.co/yzwKSTFWfl #LCSM
#LCSM Chat @lcsmchat
@Kamacintosh Hi Kim! #lcsm
Janet Freeman-Daily @JFreemanDaily
Our special guest is Lisa Rezende (@LisaRezende1), @UofA Assistant Professor of Practice in Molecular and Cellular Biology, cancer advocate, BRCA previvor, daughter of a long-term ovarian cancer survivor, and caregiver for a stepmother with metastatic breast cancer. #LCSM
#LCSM Chat @lcsmchat
Deana @LungCancerFaces tweeting from the @lcsmchat account. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Our special guest is Lisa Rezende (@LisaRezende1), @UofA Assistant Professor of Practice in Molecular and Cellular Biolo…
KC Dill @kasedill
Hello from TX excited to join everyone .#LCSM
Lisa Rezende @LisaRezende1
I'm Lisa. I teach intro biology and science outreach. I've worked and/or volunteered as a hereditary cancer patient advocate since 2011. #LCSM
Faces of Lung Cancer @LungCancerFaces
RT @JFreemanDaily: Our special guest is Lisa Rezende (@LisaRezende1), @UofA Assistant Professor of Practice in Molecular and Cellular Biolo…
Janet Freeman-Daily @JFreemanDaily
I’m your moderator Janet Freeman-Daily: writer (https://t.co/OBCc87ZwkG), science geek, stage IV #lungcancer patient/activist #LCSM
Christine Qiong Wu @wi_qiong
Hello, Bob, I see you are here. #lcsm
#LCSM Chat @lcsmchat
@kasedill Welcome! Thanks for joining. #lcsm
Sally James @jamesian
@JFreemanDaily Hi, I'm not staying for chat, but explained the value of #LCSM to an audience of about 50 on Tuesday in a suburb of #seattle. Hope some new members join. (My name is Sally, and I'm a journalist who has written about patients on social)
Bob Steele @steele_bob
Bob here from chilly Greensboro, NC #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: I'm Lisa. I teach intro biology and science outreach. I've worked and/or volunteered as a hereditary cancer patient advoc…
Jill @jillfeldman4
Hello from very cold Chicago! #LCSM
Anita Figueras @scifiknitter
Good evening all! Anita here. #LCSM
#LCSM Chat @lcsmchat
@LisaRezende1 Welcome! Thanks for being our expert this evening. #lcsm
OurWarOnCancer @OurWarOnCancer
RT @andrewjayloftis: Updates on my medical misadventures don't lend themselves to character limits, so I'll post the screenshot from Facebo…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: I’m your moderator Janet Freeman-Daily: writer (https://t.co/OBCc87ZwkG), science geek, stage IV #lungcancer patient/act…
Peggy Dennis @peggyddennis
Hello from Denver #lcsm
KC Dill @kasedill
@jillfeldman4 Hi Jill #lcsm
Dee Sparacio @womenofteal
@JFreemanDaily Dee #ovca survivor, Resaerch advocate and #gyncsm co-moderator with @btrfly12 and still forgot to use the hashtag #lcsm
Christine Qiong Wu @wi_qiong
Hello, Janet. #lcsm
#LCSM Chat @lcsmchat
@jamesian @JFreemanDaily Thank you, Sally! #lcsm
Marilyn Kempf @MarilynKempf
RT @LungCancerFaces: And 4,000+ Americans have died of lung cancer by day 10 of 2019. It's not a competition. It's a #NationalEmergency. MB…
#LCSM Chat @lcsmchat
RT @jamesian: @JFreemanDaily Hi, I'm not staying for chat, but explained the value of #LCSM to an audience of about 50 on Tuesday in a subu…
OurWarOnCancer @OurWarOnCancer
RT @JFreemanDaily: Our special guest is Lisa Rezende (@LisaRezende1), @UofA Assistant Professor of Practice in Molecular and Cellular Biolo…
#LCSM Chat @lcsmchat
@steele_bob Hey, Bob! Hope you and your wife are OK. #lcsm
#LCSM Chat @lcsmchat
@jillfeldman4 Hey, Jill! #lcsm
Janet Freeman-Daily @JFreemanDaily
@LisaRezende1 Welcome Lisa! #LCSM
#LCSM Chat @lcsmchat
@scifiknitter Hello gorgeous! #lcsm
Michigan_Yallers ❤💟 admin:Jennifer.V.Aiken @Michigan_Yaller
RT @JFreemanDaily: Our special guest is Lisa Rezende (@LisaRezende1), @UofA Assistant Professor of Practice in Molecular and Cellular Biolo…
#LCSM Chat @lcsmchat
@peggyddennis Hi Peggy! #lcsm
Lisa Rezende @LisaRezende1
Thanks for the invitation! I am not a health care provider or a researcher. My expertise is helping patients understand their cancer and options. I believe that you should not need a degree in biology to participate in shared decision making with your health care team. #LCSM
#LCSM Chat @lcsmchat
@womenofteal @JFreemanDaily @btrfly12 Welcome Dee! #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: Thanks for the invitation! I am not a health care provider or a researcher. My expertise is helping patients understand…
Janet Freeman-Daily @JFreemanDaily
If you are new to Twitter chats and/or #LCSM Chat, you might find our primer on how to participate helpful https://t.co/5g28sSQQLb #LCSM
KC Dill @kasedill
RT @LisaRezende1: Thanks for the invitation! I am not a health care provider or a researcher. My expertise is helping patients understand…
Janet Freeman-Daily @JFreemanDaily
@LisaRezende1 Absolutely awesome! #LCSM
Geri Massa @GeriGerim13
Hi ya’ll .... #LCSM
Janet Freeman-Daily @JFreemanDaily
Please remember to use #lcsm in all your tweets so others participating in the chat can see them #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: If you are new to Twitter chats and/or #LCSM Chat, you might find our primer on how to participate helpful https://t.co/…
Janet Freeman-Daily @JFreemanDaily
If you prefer just to listen, please tweet “#LCSM” so we know you’re in the audience #LCSM
#LCSM Chat @lcsmchat
@GeriGerim13 Hey Geri! #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Please remember to use #lcsm in all your tweets so others participating in the chat can see them #LCSM
Janet Freeman-Daily @JFreemanDaily
Note: Twitter allows tweets up to 280 characters, but some tweetchat apps (like https://t.co/A2M7gXQ66L) will not display tweets longer than 140. #LCSM
Lung Cancer Sux @LungCancerSux
Happy New Year! #lcsm
Kim Moran-MacIntosh 🇨🇦 @Kamacintosh
HI Jill,! #lcsm
Faces of Lung Cancer @LungCancerFaces
RT @JFreemanDaily: If you are new to Twitter chats and/or #LCSM Chat, you might find our primer on how to participate helpful https://t.co/…
Janet Freeman-Daily @JFreemanDaily
I will announce FIVE topics (T1 T2 etc). Pls label your answers with T1, T2, etc to make transcript easier to follow. #LCSM
Betsy @wildwestannie
#LCSM
#LCSM Chat @lcsmchat
@LungCancerSux Welcome! #lcsm
KC Dill @kasedill
@LungCancerSux Happy New Year #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: If you prefer just to listen, please tweet “#LCSM” so we know you’re in the audience #LCSM
KC Dill @kasedill
RT @JFreemanDaily: I will announce FIVE topics (T1 T2 etc). Pls label your answers with T1, T2, etc to make transcript easier to follow. #…
Janet Freeman-Daily @JFreemanDaily
T1: Why doesn’t the immune system prevent cancer? #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Note: Twitter allows tweets up to 280 characters, but some tweetchat apps (like https://t.co/A2M7gXQ66L) will not displa…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: I will announce FIVE topics (T1 T2 etc). Pls label your answers with T1, T2, etc to make transcript easier to follow. #…
#LCSM Chat @lcsmchat
@wildwestannie We see you! #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T1: Why doesn’t the immune system prevent cancer? #LCSM
Bob Steele @steele_bob
RT @JFreemanDaily: T1: Why doesn’t the immune system prevent cancer? #LCSM
Jill @jillfeldman4
RT @JFreemanDaily: T1: Why doesn’t the immune system prevent cancer? #LCSM
Betsy Mullen @betsymullen
RT @NCICancerStats: Every year, ~7,330 lung cancer deaths occur among adult nonsmokers in the United States as a result of #secondhandsmoke
Stephen V Liu @StephenVLiu
T1: it does prevent cancer - but cancers can evolve many different ways to escape immune surveillance - such as expression of PDL1 among others #LCSM
Jill @jillfeldman4
T1 Cancer finds a way to evade our immune system #LCSM
Lung Cancer Sux @LungCancerSux
Where is @BrendonStilesMD when we need him #lcsm
#LCSM Chat @lcsmchat
RT @StephenVLiu: T1: it does prevent cancer - but cancers can evolve many different ways to escape immune surveillance - such as expression…
#LCSM Chat @lcsmchat
RT @jillfeldman4: T1 Cancer finds a way to evade our immune system #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T1: Why doesn’t the immune system prevent cancer? #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @StephenVLiu: T1: it does prevent cancer - but cancers can evolve many different ways to escape immune surveillance - such as expression…
#LCSM Chat @lcsmchat
@StephenVLiu Elaborate, please? #lcsm
Lisa Rezende @LisaRezende1
T1 A properly functioning immune system must recognize and eliminate pathogens (bacteria, viruses, and parasites) and harmful cells without hurting healthy cells. #LCSM
Janet Freeman-Daily @JFreemanDaily
Our cells have tumor suppression mechanisms, but sometimes they don't recognize a cell is "Not Me." #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1 A properly functioning immune system must recognize and eliminate pathogens (bacteria, viruses, and parasites) and har…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Our cells have tumor suppression mechanisms, but sometimes they don't recognize a cell is "Not Me." #LCSM
Timothy Craig Allen @TimAllenMDJD
Often cancer cells molecularly "trick" the immune system into not recognizing them as abnormal cells. #LCSM
Lisa Rezende @LisaRezende1
T1. Cells have markers on their surface, called antigens, that help the immune system determine if the cell is healthy or not. #LCSM
Jill @jillfeldman4
T1 But it's puzzling and don't know exactly why it happens in some people and not others. Where/what is the breakdown and why? #LCSM
Kim Moran-MacIntosh 🇨🇦 @Kamacintosh
actually use immune cells to facilitate their attack on the body. #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: Our cells have tumor suppression mechanisms, but sometimes they don't recognize a cell is "Not Me." #LCSM
Ildiko Medve @MedveIldiko
RT @lgreco_ny: Podcast in which I'm featured talking about patient advocacy and clinical trials. @MassBio @bjork5 #lcsm https://t.co/T99jk…
Bob Steele @steele_bob
RT @LisaRezende1: T1. Cells have markers on their surface, called antigens, that help the immune system determine if the cell is healthy or…
#LCSM Chat @lcsmchat
RT @TimAllenMDJD: Often cancer cells molecularly "trick" the immune system into not recognizing them as abnormal cells. #LCSM https://t.co/…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. Cells have markers on their surface, called antigens, that help the immune system determine if the cell is healthy or…
#LCSM Chat @lcsmchat
RT @jillfeldman4: T1 But it's puzzling and don't know exactly why it happens in some people and not others. Where/what is the breakdown and…
Lisa Rezende @LisaRezende1
If the immune system recognizes the marker as belong there (sometimes called self) then it does not attack the cell. If the immune systems does not then it will mount an immune response. #LCSM
Bob Steele @steele_bob
RT @lgreco_ny: Podcast in which I'm featured talking about patient advocacy and clinical trials. @MassBio @bjork5 #lcsm https://t.co/T99jk…
Stephen V Liu @StephenVLiu
@lcsmchat Our immune system will recognize and eliminate cancers - cancers that happen to have certain characteristics that allow escape (by chance) are the ones that survive. Our system selects for these cancers (immunoediting). #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: If the immune system recognizes the marker as belong there (sometimes called self) then it does not attack the cell. If…
Janet Freeman-Daily @JFreemanDaily
I know @LisaRezende1 has some cool slides prepared for this chat--apparently her Internet connection isn't letting the images post. Pooh. Hopefully she can post them later. #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @LisaRezende1: If the immune system recognizes the marker as belong there (sometimes called self) then it does not attack the cell. If…
Timothy Craig Allen @TimAllenMDJD
RT @StephenVLiu: @lcsmchat Our immune system will recognize and eliminate cancers - cancers that happen to have certain characteristics tha…
Lisa Rezende @LisaRezende1
T1. Cancer cells develop when a series of changes to the cell's DNA affect the mechanisms that control how the cell divides. Some of these changes lead to new marker on the cell surface. #LCSM
Lisa Rezende @LisaRezende1
T1. If the immune system identifies the new marker as abonormal, it will attack and eliminate the cancer cell. #LCSM
✌️24/7 WWW News 🇺🇸 @tvanon1
RT @NCICancerStats: Every year, ~7,330 lung cancer deaths occur among adult nonsmokers in the United States as a result of #secondhandsmoke
#LCSM Chat @lcsmchat
RT @StephenVLiu: @lcsmchat Our immune system will recognize and eliminate cancers - cancers that happen to have certain characteristics tha…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: I know @LisaRezende1 has some cool slides prepared for this chat--apparently her Internet connection isn't letting the i…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. Cancer cells develop when a series of changes to the cell's DNA affect the mechanisms that control how the cell divid…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. If the immune system identifies the new marker as abonormal, it will attack and eliminate the cancer cell. #LCSM
Dee Sparacio @womenofteal
RT @LisaRezende1: If the immune system recognizes the marker as belong there (sometimes called self) then it does not attack the cell. If…
Dee Sparacio @womenofteal
RT @LisaRezende1: T1. Cancer cells develop when a series of changes to the cell's DNA affect the mechanisms that control how the cell divid…
Lisa Rezende @LisaRezende1
T1. In some cases, the immune system cannot eliminate the cancer cell but can keep the cell from growing out of control. This phase, where tumor growth is kept under control is called equilibrium. #LCSM
Janet Freeman-Daily @JFreemanDaily
Our cells' DNA acquire mutations over time as they make copies of themselves, and/or are exposed to something that causes them to mutate. The immune system SHOULD recognize those cells as "Not Me," but for some reason that doesn't always work. #LCSM
Stephen V Liu @StephenVLiu
By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint inhibitors are just the start! #LCSM
Lisa Rezende @LisaRezende1
T1. If a tumor has formed and spread, then it has developed a way to evade the immune system-- sometimes called escape. #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. In some cases, the immune system cannot eliminate the cancer cell but can keep the cell from growing out of control.…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Our cells' DNA acquire mutations over time as they make copies of themselves, and/or are exposed to something that cause…
#LCSM Chat @lcsmchat
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Janet Freeman-Daily @JFreemanDaily
T2: What types of immunotherapy have been approved? #LCSM
Dee Sparacio @womenofteal
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. If a tumor has formed and spread, then it has developed a way to evade the immune system-- sometimes called escape.…
KC Dill @kasedill
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Dee Sparacio @womenofteal
RT @JFreemanDaily: Our cells' DNA acquire mutations over time as they make copies of themselves, and/or are exposed to something that cause…
Lisa Rezende @LisaRezende1
T1. Immunotherapy treatments help the immune system regain control of the cancer cells. #LCSM
Jill @jillfeldman4
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Emily Drake @EK_Drake
RT @JFreemanDaily: Welcome to the first #LCSM Chat of 2019! We’ve shifted to monthly chats this year. Tonight we’re hosting a collaborative…
Fred Gray @fcgiii
T1 a cancer cell is a normal cell and has the required markers to identify is as a good guy. But it exhibits uncontrolled growth. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T1. Immunotherapy treatments help the immune system regain control of the cancer cells. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T2: What types of immunotherapy have been approved? #LCSM
#LCSM Chat @lcsmchat
RT @fcgiii: T1 a cancer cell is a normal cell and has the required markers to identify is as a good guy. But it exhibits uncontrolled growt…
Lisa Rezende @LisaRezende1
T2. Just as there are different types of chemotherapies, there are different types of immunotherapies. #LCSM
Bob Steele @steele_bob
Surprised to learn that immuno drugs are "targeted" like precision tx. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. Just as there are different types of chemotherapies, there are different types of immunotherapies. #LCSM
#LCSM Chat @lcsmchat
RT @steele_bob: Surprised to learn that immuno drugs are "targeted" like precision tx. #lcsm
Dee Sparacio @womenofteal
Checkpoint inhibitors that target PD-1 like Keytruda is one that comes to mind. #lcsm
Anita Figueras @scifiknitter
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Janet Freeman-Daily @JFreemanDaily
Lisa's wonderful prepared tweets are not going through for some reasons ... #LCSM
Lisa Rezende @LisaRezende1
T2. While all of these therapies help the immune system fight cancer, different types have been approved for different cancers. The patient experience will depend on the type of therapy they recieve. #LCSM
#LCSM Chat @lcsmchat
RT @womenofteal: Checkpoint inhibitors that target PD-1 like Keytruda is one that comes to mind. #lcsm
Brendon Stiles @BrendonStilesMD
Joining in from road with bad connection! Just spent all day talking lung cancer. How is everyone?! I miss all of you. Happy new year! #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Lisa's wonderful prepared tweets are not going through for some reasons ... #LCSM
Christine Qiong Wu @wi_qiong
How does PD-1 and PD-?1 work? #lcsm
SunshineKK @SunshineKK68
How does Keytruda work with chemotherapies even without PDL1? #lcsm
KC Dill @kasedill
T2 Nivolumab is another approved checkpoint inhibitor. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. While all of these therapies help the immune system fight cancer, different types have been approved for different ca…
Bob Steele @steele_bob
How do immuno drugs differ from antibiotics? #lcsm
Lisa Rezende @LisaRezende1
T2. Adoptive cell transfer therapies use the patient's own immune cell. An example is CAR T-cell therapy, which is approved for some blood cancers. #LCSM
Nicole Kuderer @NicoleKuderer
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Brendon Stiles @BrendonStilesMD
Where are we in this whole conversation? #lcsm
Aparna Hegde, MD @notahedge
T1 T-cells are like cops, patrolling the body for bad guys which may be bacteria/viruses/even 🦀 cells. Normal cells express proteins on their surface to let the T cells knw tht they belong in the body ex: PDL1. 🦀 cells escape killing by Tcells by expressing the same PDL1. #LCSM
Lecia Sequist, MD, MPH @LeciaSequist
Hi twitter buddies! Joining the chat briefly from Boston. Lung cancer medical oncologist. Immune therapy has been a game changer in lung cancer (yes, I said game changer) #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @LisaRezende1: T2. Adoptive cell transfer therapies use the patient's own immune cell. An example is CAR T-cell therapy, which is appro…
KC Dill @kasedill
@BrendonStilesMD Hello T2 #LCSM
#LCSM Chat @lcsmchat
@BrendonStilesMD We miss you, too! Don't worry--you're moderating the Feb chat. xo #lcsm
Betsy @wildwestannie
What is the checkpoint that is inhibited? #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @notahedge: T1 T-cells are like cops, patrolling the body for bad guys which may be bacteria/viruses/even 🦀 cells. Normal cells express…
Lisa Rezende @LisaRezende1
T2. Most patients think of vaccines in terms of prevention. In immunotherapy, cancer vaccines are used for treatment. These are often called therapeutic vaccines. #LCSM
Gia Sonata @RedGia
#lcsm - late but here.
#LCSM Chat @lcsmchat
RT @LeciaSequist: Hi twitter buddies! Joining the chat briefly from Boston. Lung cancer medical oncologist. Immune therapy has been a game…
MaryAnn Bradley @Dollybrad
@BrendonStilesMD Happy new year #LCSM
KC Dill @kasedill
@LeciaSequist Hello! I will take game changer.. #LCSM
Janet Freeman-Daily @JFreemanDaily
@BrendonStilesMD We're on T2, but Twitter is misbehaving so we're behind on our tweets. #LCSM
#LCSM Chat @lcsmchat
@LeciaSequist Yippee! Hi there. #lcsm
Lisa Rezende @LisaRezende1
T2. Cancer therapeutic vaccines train the immune system to recognize and eliminate cancer cells. Most are still in clinical trials but there is one approved for prostate cancer. #LCSM
Brendon Stiles @BrendonStilesMD
@lcsmchat Going to bring the A-game and get the A-listers out in force. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. Adoptive cell transfer therapies use the patient's own immune cell. An example is CAR T-cell therapy, which is appro…
#LCSM Chat @lcsmchat
RT @notahedge: T1 T-cells are like cops, patrolling the body for bad guys which may be bacteria/viruses/even 🦀 cells. Normal cells express…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. Most patients think of vaccines in terms of prevention. In immunotherapy, cancer vaccines are used for treatment. T…
Bob Steele @steele_bob
RT @BrendonStilesMD: @lcsmchat Going to bring the A-game and get the A-listers out in force. #lcsm
#LCSM Chat @lcsmchat
@RedGia Hi there! #lcsm
Brendon Stiles @BrendonStilesMD
@kasedill @LeciaSequist Who doesn't love a good game changer!? #lcsm
Janet Freeman-Daily @JFreemanDaily
@wildwestannie There is more than one type of checkpoint inhibitor. One types blocks the PD-1 pathway. Another blocks the CT4 pathway. Others are in development. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @BrendonStilesMD We're on T2, but Twitter is misbehaving so we're behind on our tweets. #LCSM
Dee Sparacio @womenofteal
T2 @AmericanCancer has a great page on Immune Checkpoint inhibitors and how they work https://t.co/cCIjr2pvWm #lcsm
Janet Freeman-Daily @JFreemanDaily
T3: How can we tell if immunotherapy will work for my cancer? #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. Cancer therapeutic vaccines train the immune system to recognize and eliminate cancer cells. Most are still in clini…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @wildwestannie There is more than one type of checkpoint inhibitor. One types blocks the PD-1 pathway. Another blocks…
MaryAnn Bradley @Dollybrad
#LCSM
#LCSM Chat @lcsmchat
RT @womenofteal: T2 @AmericanCancer has a great page on Immune Checkpoint inhibitors and how they work https://t.co/cCIjr2pvWm #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @womenofteal: T2 @AmericanCancer has a great page on Immune Checkpoint inhibitors and how they work https://t.co/cCIjr2pvWm #lcsm
Lisa Rezende @LisaRezende1
T2. This therapeutic vaccine is more complicated than a shot. Immune cells are isolated from a patient's blood, then trained to recognize the cancer. Finally, the cells are given back to the patient so they will attack the cancer. #LCSM
Bob Steele @steele_bob
RT @womenofteal: T2 @AmericanCancer has a great page on Immune Checkpoint inhibitors and how they work https://t.co/cCIjr2pvWm #lcsm
Betsy @wildwestannie
RT @JFreemanDaily: @wildwestannie There is more than one type of checkpoint inhibitor. One types blocks the PD-1 pathway. Another blocks…
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: @wildwestannie There is more than one type of checkpoint inhibitor. One types blocks the PD-1 pathway. Another blocks…
Aparna Hegde, MD @notahedge
T2 There are diff types of immunotherapies. But all of them leverage our own immune system to kill 🦀 #LCSM
KC Dill @kasedill
RT @JFreemanDaily: T3: How can we tell if immunotherapy will work for my cancer? #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. This therapeutic vaccine is more complicated than a shot. Immune cells are isolated from a patient's blood, then trai…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. This therapeutic vaccine is more complicated than a shot. Immune cells are isolated from a patient's blood, then trai…
Brendon Stiles @BrendonStilesMD
T2. Lots of great drugs, each used in sometimes different contexts. Many have not been tried head to head but there are probably differences in efficacy. #lcsm
Bob Steele @steele_bob
RT @notahedge: T2 There are diff types of immunotherapies. But all of them leverage our own immune system to kill 🦀 #LCSM
#LCSM Chat @lcsmchat
@Dollybrad Hi MaryAnn! #lcsm
#LCSM Chat @lcsmchat
RT @notahedge: T2 There are diff types of immunotherapies. But all of them leverage our own immune system to kill 🦀 #LCSM
Lisa Rezende @LisaRezende1
T2. Checkpoint inhibitors are what we see most often in the headlines today. #LCSM
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T2. Lots of great drugs, each used in sometimes different contexts. Many have not been tried head to head but there…
Janet Freeman-Daily @JFreemanDaily
@LisaRezende1 CimaVax is a therapeutic vaccine in clinical trials for #lungcancer. It's approved in Cuba and some other countries, but is still being evaluated in the US. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T3: How can we tell if immunotherapy will work for my cancer? #LCSM
Dee Sparacio @womenofteal
RT @LisaRezende1: T2. Most patients think of vaccines in terms of prevention. In immunotherapy, cancer vaccines are used for treatment. T…
Brendon Stiles @BrendonStilesMD
T3. Great question for which we need more research. Tumor PD-L1 expression is best segregator now, but not perfect. #lcsm
Janet Freeman-Daily @JFreemanDaily
@womenofteal @AmericanCancer Thanks Dee! #LCSM
Brendon Stiles @BrendonStilesMD
T3. How many total mutations your tumor has (TMB) may also be an important predictor. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. Checkpoint inhibitors are what we see most often in the headlines today. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @LisaRezende1 CimaVax is a therapeutic vaccine in clinical trials for #lungcancer. It's approved in Cuba and some other…
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T3. Great question for which we need more research. Tumor PD-L1 expression is best segregator now, but not perfect.…
Lisa Rezende @LisaRezende1
So happy to see everyone sharing links- Twitter is not letting me cut and past right now so I can't provide the links I've collected! #LCSM
Lecia Sequist, MD, MPH @LeciaSequist
@JFreemanDaily T3 This is the million dollar question. We have a biomarker that predicts likelihood of response to CPI (PDL1 staining) but it is a mediocre predictor - nothing like the biomarkers for targeted therapy. Good news: in lung cancer chemo + IO works well regardless of PD1. #LCSM
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T3. How many total mutations your tumor has (TMB) may also be an important predictor. #lcsm
Bob Steele @steele_bob
RT @BrendonStilesMD: T3. How many total mutations your tumor has (TMB) may also be an important predictor. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: So happy to see everyone sharing links- Twitter is not letting me cut and past right now so I can't provide the links I'v…
Dee Sparacio @womenofteal
Yes we hear more and more about TMB . #lcsm
Stephen V Liu @StephenVLiu
T3: Unfortunately we don’t have a perfect predictor of whether immunotherapy will work or not. For now, it should be part of standard therapy for anyone with stage 4 lung cancer that does not have a driver mutation like EGFR or ALK #LCSM
Aparna Hegde, MD @notahedge
T2 Broadly, 1. Vaccines 2. CART cell therapies 3. Checkpoint inhibitors. Several other modulators of the immune system are being researched. #LCSM
gilberto lopes @GlopesMd
RT @StephenVLiu: By understanding how cancers escape immune surveillance, we can develop strategies to restore immune control. Checkpoint i…
Brendon Stiles @BrendonStilesMD
T3. Unfortunately, right now if you have EGFR+ or ALK+ lung cancer, immuno probably WON'T work. Lots of trials to figure out ways to improve this. #lcsm
SunshineKK @SunshineKK68
How does Keytruda enhance chemotherapy even without PD-L1 expression? #lcsm
#LCSM Chat @lcsmchat
@LisaRezende1 We can work on the links after the chat. Thanks for trying. #lcsm
Timothy Craig Allen @TimAllenMDJD
Jury is still out on it. #lcsm
#LCSM Chat @lcsmchat
RT @LeciaSequist: @JFreemanDaily T3 This is the million dollar question. We have a biomarker that predicts likelihood of response to CPI (P…
jane stewart @yaaintseenothin
RT @fcgiii: T1 a cancer cell is a normal cell and has the required markers to identify is as a good guy. But it exhibits uncontrolled growt…
#LCSM Chat @lcsmchat
RT @StephenVLiu: T3: Unfortunately we don’t have a perfect predictor of whether immunotherapy will work or not. For now, it should be part…
Janet Freeman-Daily @JFreemanDaily
@BrendonStilesMD PD-L1 pathway (same as PD-1 pathway) is the best immunotherapy for #lungcancer, but not necessarily for ALL cancers. Remember, this is a collaborative chat across cancer types. #LCSM
#LCSM Chat @lcsmchat
RT @notahedge: T2 Broadly, 1. Vaccines 2. CART cell therapies 3. Checkpoint inhibitors. Several other modulators of the immune system are b…
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T3. Unfortunately, right now if you have EGFR+ or ALK+ lung cancer, immuno probably WON'T work. Lots of trials to fi…
Timothy Craig Allen @TimAllenMDJD
Lots of questions still to answer. #lcsm
#LCSM Chat @lcsmchat
RT @TimAllenMDJD: Jury is still out on it. #lcsm https://t.co/SgYwirI0PW
Timothy Craig Allen @TimAllenMDJD
RT @StephenVLiu: T3: Unfortunately we don’t have a perfect predictor of whether immunotherapy will work or not. For now, it should be part…
Lisa Rezende @LisaRezende1
T2. In normal conditions, the checkpoint acts as "brakes" to keep the immune system from attacking healthy cells. When some cancer cells escape, they use those "brakes" to evade the immune system. #LCSM
Aparna Hegde, MD @notahedge
T2 antibiotics are to bacteria/virus/fungi what chemotherapy is to cancer. They directly attack the cells. #LCSM
#LCSM Chat @lcsmchat
RT @SunshineKK68: How does Keytruda enhance chemotherapy even without PD-L1 expression? #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @BrendonStilesMD PD-L1 pathway (same as PD-1 pathway) is the best immunotherapy for #lungcancer, but not necessarily for…
Brendon Stiles @BrendonStilesMD
@SunshineKK68 Another great question. More likely that chemo may enhance the immune response by killing some cells and exposing tumor proteins which the immune system can recognize. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T2. In normal conditions, the checkpoint acts as "brakes" to keep the immune system from attacking healthy cells. When so…
#LCSM Chat @lcsmchat
RT @notahedge: T2 antibiotics are to bacteria/virus/fungi what chemotherapy is to cancer. They directly attack the cells. #LCSM
Bob Steele @steele_bob
RT @notahedge: T2 antibiotics are to bacteria/virus/fungi what chemotherapy is to cancer. They directly attack the cells. #LCSM
Lecia Sequist, MD, MPH @LeciaSequist
@BrendonStilesMD Very true @BrendonStilesMD and lack of IO efficacy probably extrapolates to other oncogene-driven cancers like MET e14, ROS, RET #LCSM
Kim Moran-MacIntosh 🇨🇦 @Kamacintosh
RT @notahedge: T2 antibiotics are to bacteria/virus/fungi what chemotherapy is to cancer. They directly attack the cells. #LCSM
Timothy Craig Allen @TimAllenMDJD
Testing is likely going to be valuable in the future as we learn more. #lcsm
Dee Sparacio @womenofteal
RT @BrendonStilesMD: @SunshineKK68 Another great question. More likely that chemo may enhance the immune response by killing some cells an…
Timothy Craig Allen @TimAllenMDJD
RT @LeciaSequist: @BrendonStilesMD Very true @BrendonStilesMD and lack of IO efficacy probably extrapolates to other oncogene-driven cancer…
#LCSM Chat @lcsmchat
@lcsmchat The impact created by the immune therapy in treatment of lung cancer is remarkable. While its effectiveness in bladder cancer and cervical cancer is also proven, its utility for breast cancer is waiting FDA approval. (From @israhkhan) #lcsm
Lisa Rezende @LisaRezende1
T3. Tumor DNA tests that look for defects in the cancer cell's ability to repair mistakes in DNA are also used to indicate that a cancer might respond to immunotherapy. #LCSM
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: @SunshineKK68 Another great question. More likely that chemo may enhance the immune response by killing some cells an…
Aparna Hegde, MD @notahedge
RT @LeciaSequist: @JFreemanDaily T3 This is the million dollar question. We have a biomarker that predicts likelihood of response to CPI (P…
#LCSM Chat @lcsmchat
RT @LeciaSequist: @BrendonStilesMD Very true @BrendonStilesMD and lack of IO efficacy probably extrapolates to other oncogene-driven cancer…
#LCSM Chat @lcsmchat
RT @TimAllenMDJD: Testing is likely going to be valuable in the future as we learn more. #lcsm https://t.co/7SIYmCGGIc
Betsy @wildwestannie
RT @LisaRezende1: T2. In normal conditions, the checkpoint acts as "brakes" to keep the immune system from attacking healthy cells. When so…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T3. Tumor DNA tests that look for defects in the cancer cell's ability to repair mistakes in DNA are also used to indicat…
KC Dill @kasedill
@BrendonStilesMD @SunshineKK68 I keep forgetting #LCSM
Timothy Craig Allen @TimAllenMDJD
Tumor microenvironment probably plays a role. Not yet completely defined. #lcsm
Bob Steele @steele_bob
From trial results, most folks have multiple driver mutations. Have seen pts with up to 15 mutations. That's got to make immuno tough #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @lcsmchat: @lcsmchat The impact created by the immune therapy in treatment of lung cancer is remarkable. While its effectiveness in blad…
Brendon Stiles @BrendonStilesMD
Was at a great panel for ⁦@AstraZeneca⁩ today with ⁦@redsoxdoc11⁩ and ⁦@benlevylungdoc⁩ today discussing immunotherapy and EGFR targeted therapy. #lcsm https://t.co/CvRYUm4hxq
Stephen V Liu @StephenVLiu
@LeciaSequist @BrendonStilesMD Definitely @LeciaSequist, with the possible exception being BRAF. But more study is needed #LCSM
Bob Steele @steele_bob
RT @TimAllenMDJD: Tumor microenvironment probably plays a role. Not yet completely defined. #lcsm https://t.co/vX0AWPf7Qp
#LCSM Chat @lcsmchat
RT @TimAllenMDJD: Tumor microenvironment probably plays a role. Not yet completely defined. #lcsm https://t.co/vX0AWPf7Qp
#LCSM Chat @lcsmchat
RT @steele_bob: From trial results, most folks have multiple driver mutations. Have seen pts with up to 15 mutations. That's got to make im…
#LCSM Chat @lcsmchat
RT @StephenVLiu: @LeciaSequist @BrendonStilesMD Definitely @LeciaSequist, with the possible exception being BRAF. But more study is needed…
Brendon Stiles @BrendonStilesMD
@kasedill @SunshineKK68 Provocative question. PACIFIC trial and a trial we have underway show a signal that radiation may help prime immune response, but data still early and needs more study. #lcsm
Janet Freeman-Daily @JFreemanDaily
T3: The upshot is that we have some tests that are designed to help determine those for whom immunotherapy will work, but they're not very accurate yet. We need better biomarkers. #LCSM
Lisa Rezende @LisaRezende1
T3. There is a checkpoint inhibitor approved for all tumors that have high microsatellite instability, regardless of type. Cancer associated with Lynch syndrome have this defect. #LCSM
#LCSM Chat @lcsmchat
"Will being pretreated with IMRT enhance the response as well?" (From @kasedill) #lcsm
Bob Steele @steele_bob
Clearly it's a multifactorial microenvironment. Hard computational issues. #lcsm
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: @kasedill @SunshineKK68 Provocative question. PACIFIC trial and a trial we have underway show a signal that radiation…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T3: The upshot is that we have some tests that are designed to help determine those for whom immunotherapy will work, b…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T3. There is a checkpoint inhibitor approved for all tumors that have high microsatellite instability, regardless of type…
Brendon Stiles @BrendonStilesMD
@TimAllenMDJD Key area of work for pathology. Has to be important! #lcsm
MaryAnn Bradley @Dollybrad
RT @BrendonStilesMD: @kasedill @SunshineKK68 Provocative question. PACIFIC trial and a trial we have underway show a signal that radiation…
#LCSM Chat @lcsmchat
RT @steele_bob: Clearly it's a multifactorial microenvironment. Hard computational issues. #lcsm
Janet Freeman-Daily @JFreemanDaily
@steele_bob Actually, it's rare for people to have multiple DRIVER mutations. There are many other mutations that are not consider the primary driver of the cancer. People with more mutations seem to do better on immunotherapy, which is why people are studying Tumor Mutation Burden. #LCSM
Cecília Arraes @CeciliaArraes
RT @JTOonline: In this JTO Editor's Choice, Eguchi and colleagues evaluate the association between the outcome of patients with STAS receiv…
Janet Freeman-Daily @JFreemanDaily
T4: What are the downsides of immunotherapy? #LCSM
CU Cancer Center @CUCancerCenter
Brigatinib becomes potential new first-line option for ALK-positive non-small lung cancer https://t.co/rsYIQtbTlp #LCSM #lungcancer @IASLC https://t.co/UL7VjbkjCT
Dee Sparacio @womenofteal
T3 @FacingOurRisk also describes immunotherapies - monoclonal antibodies, check pt inhibitors, vaccines etc https://t.co/y0uwjInH81 #lcsm #gyncsm
Lisa Rezende @LisaRezende1
T3. NCCN patient guidelines have useful information on currently approved therapies for different cancer, written in language patients can understand. These handbooks can help patients discuss options with their providers. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @steele_bob Actually, it's rare for people to have multiple DRIVER mutations. There are many other mutations that are n…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T4: What are the downsides of immunotherapy? #LCSM
Cecília Arraes @CeciliaArraes
RT @IASLC: “Cancer Statistics, 2019,” @AmericanCancer's report on cancer rates/trends, shows a 27% drop in the overall cancer death rate in…
#LCSM Chat @lcsmchat
RT @womenofteal: T3 @FacingOurRisk also describes immunotherapies - monoclonal antibodies, check pt inhibitors, vaccines etc https://t.co/y…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T3. NCCN patient guidelines have useful information on currently approved therapies for different cancer, written in lang…
Lisa Rezende @LisaRezende1
T3. The NCCN patient guidelines for melanoma and lung cancer both have nice discussions of approved immunotherapies. #LCSM
Brendon Stiles @BrendonStilesMD
T4. Can't let the hype set false expectations. Important to recognize that most patients may not respond. But also important to have hope and excitement. #lcsm
Janet Freeman-Daily @JFreemanDaily
@lcsmchat @kasedill Several studies are examining the value of combining radiation therapy with immunotherapy. Looks promising, but jury's still out. #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T4: What are the downsides of immunotherapy? #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @BrendonStilesMD: @TimAllenMDJD Key area of work for pathology. Has to be important! #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @steele_bob: Clearly it's a multifactorial microenvironment. Hard computational issues. #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T3. The NCCN patient guidelines for melanoma and lung cancer both have nice discussions of approved immunotherapies. #LC
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T4. Can't let the hype set false expectations. Important to recognize that most patients may not respond. But also…
Timothy Craig Allen @TimAllenMDJD
RT @lcsmchat: "Will being pretreated with IMRT enhance the response as well?" (From @kasedill) #lcsm https://t.co/7zybBhvIzQ
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @lcsmchat @kasedill Several studies are examining the value of combining radiation therapy with immunotherapy. Looks pr…
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T3: The upshot is that we have some tests that are designed to help determine those for whom immunotherapy will work, b…
Janet Freeman-Daily @JFreemanDaily
@LisaRezende1 NCCN Patient Guidelines are here: https://t.co/rxLWK1uLJL #LCSM
Brendon Stiles @BrendonStilesMD
T4. IO has a whole different set of immune related side effects. Many physicians may not be as aware. Important to recognize and treat early. #lcsm
Bob Steele @steele_bob
I put together Excel workbook with lung cancer gene mutations reported in 11 trials. Let me know if you want a copy. #lcsm
Lecia Sequist, MD, MPH @LeciaSequist
@JFreemanDaily T4 Two major downsides I see everyday in clinic: IO doesn't work for everyone (which is very disappointing to folks given the hype) and the side effects, which don't happen to everyone but can in rare cases be quite serious #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @LisaRezende1 NCCN Patient Guidelines are here: https://t.co/rxLWK1uLJL #LCSM
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T4. IO has a whole different set of immune related side effects. Many physicians may not be as aware. Important to…
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: @LisaRezende1 NCCN Patient Guidelines are here: https://t.co/rxLWK1uLJL #LCSM
KC Dill @kasedill
@steele_bob Bob count me in #LCSM
Brendon Stiles @BrendonStilesMD
T4. What do medical oncologists think about the idea of hyperprogression? A very small proportion of patients may have rapid progression of disease. #lcsm
#LCSM Chat @lcsmchat
RT @LeciaSequist: @JFreemanDaily T4 Two major downsides I see everyday in clinic: IO doesn't work for everyone (which is very disappointing…
Lisa Rezende @LisaRezende1
T4. Many articles on immunotherapy describe "harnessing" the immune system. Some patients describe it as "unleashing." This very active immune response can have side effects #LCSM
Cecília Arraes @CeciliaArraes
RT @JCO_ASCO: Updated analysis of KEYNOTE-024 - pembrolizumab vs platinum-based chemo for advanced NSCLC https://t.co/cy67qos7Be #lcsm #imm
Gia Sonata @RedGia
@JFreemanDaily #lcsm DARN! I forgot T4 and #lcsm sorry! I'm going to delete and repost.
#LCSM Chat @lcsmchat
RT @BrendonStilesMD: T4. What do medical oncologists think about the idea of hyperprogression? A very small proportion of patients may ha…
Brendon Stiles @BrendonStilesMD
@LeciaSequist @StephenVLiu #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T4. Many articles on immunotherapy describe "harnessing" the immune system. Some patients describe it as "unleashing." T…
Dee Sparacio @womenofteal
@JFreemanDaily T4 Side -effects comes to mind . @SITcancer has come up with recommendations "most side effects from checkpoint inhibitors are mild to moderate and can be treated with drugs that temporarily suppress the immune system. " #lcsm .https://t.co/JVnyZBQx9o
KC Dill @kasedill
RT @LisaRezende1: T4. Many articles on immunotherapy describe "harnessing" the immune system. Some patients describe it as "unleashing." T…
Janet Freeman-Daily @JFreemanDaily
T4: Important to recognized that immunotherapy is not without side effects. Some people have few side effects. Some have severe side effects, which may be permanent. #LCSM
Timothy Craig Allen @TimAllenMDJD
#EvidenceBasedMedicine #SkipTheHype #PatientsFirst #lcsm
Timothy Craig Allen @TimAllenMDJD
RT @womenofteal: @JFreemanDaily T4 Side -effects comes to mind . @SITcancer has come up with recommendations "most side effects from checkp…
Betsy @wildwestannie
RT @BrendonStilesMD: T4. What do medical oncologists think about the idea of hyperprogression? A very small proportion of patients may ha…
#LCSM Chat @lcsmchat
RT @womenofteal: @JFreemanDaily T4 Side -effects comes to mind . @SITcancer has come up with recommendations "most side effects from checkp…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T4: Important to recognized that immunotherapy is not without side effects. Some people have few side effects. Some ha…
Bob Steele @steele_bob
Seems that many non-Driver mutations are catalysts. #lcsm
Lisa Rezende @LisaRezende1
T4. ASCO and NCCN have guidelines on recognizing and managing the side effects of immunotherapies. A list of side effects is published on the ASCO https://t.co/w1RA7HdPrv site (I still can't paste links!) #LCSM
Janet Freeman-Daily @JFreemanDaily
RT @LeciaSequist: @JFreemanDaily T4 Two major downsides I see everyday in clinic: IO doesn't work for everyone (which is very disappointing…
Anita Figueras @scifiknitter
RT @JFreemanDaily: @LisaRezende1 NCCN Patient Guidelines are here: https://t.co/rxLWK1uLJL #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T4: Important to recognized that immunotherapy is not without side effects. Some people have few side effects. Some ha…
Gia Sonata @RedGia
@JFreemanDaily T4: #LCSM: Attacks on healthy tissue/glands: I'm now cortisol dependent due to IO therapy damaged pituitary which lead to adrenals not functioning correctly. Thyroid was the 1st to go. Base lines of all 3 should be established prior to 1st IO infusion imo. We only did thyroid.
Brendon Stiles @BrendonStilesMD
Have to drop off. Sorry for the brief cameo. Get ready for February!!! @lcsmchat #lcsm
Aparna Hegde, MD @notahedge
@lcsmchat @kasedill It may be so due to a phenomenon called abscopal effect. XRT to 1 lesion may result in shrinkage of other lesions elsewhere in the body. This is believed to be due to XRT stimulating the immune system via a number of mechanisms. Combining IO with XRT has strong rationale #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T4. ASCO and NCCN have guidelines on recognizing and managing the side effects of immunotherapies. A list of side effect…
#LCSM Chat @lcsmchat
RT @RedGia: @JFreemanDaily T4: #LCSM: Attacks on healthy tissue/glands: I'm now cortisol dependent due to IO therapy damaged pituitary whic…
#LCSM Chat @lcsmchat
RT @notahedge: @lcsmchat @kasedill It may be so due to a phenomenon called abscopal effect. XRT to 1 lesion may result in shrinkage of othe…
KC Dill @kasedill
@BrendonStilesMD @lcsmchat Thanks as always #LCSM
Gia Sonata @RedGia
@BrendonStilesMD #lcsm - Is this the same as "pseudo-progression"?
Timothy Craig Allen @TimAllenMDJD
RT @notahedge: @lcsmchat @kasedill It may be so due to a phenomenon called abscopal effect. XRT to 1 lesion may result in shrinkage of othe…
Lisa Rezende @LisaRezende1
T4. I agree hype can be frustrating for patients. It is important to remember we aren't there yet for all cancers or all patients with a cancer that has an approved IO. Health care providers need patients understand if it is an option for them #LCSM
Aparna Hegde, MD @notahedge
@lcsmchat @kasedill Trials testing this combination are underway. The Pacific trial showed that pts who started durvalumab within 14 days of completing XRT had better outcomes.#LCSM
Vamsi Velcheti, MD @VamsiVelcheti
Joining from New York @nyulangone #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T4. I agree hype can be frustrating for patients. It is important to remember we aren't there yet for all cancers or all…
#LCSM Chat @lcsmchat
RT @notahedge: @lcsmchat @kasedill Trials testing this combination are underway. The Pacific trial showed that pts who started durvalumab w…
Anita Figueras @scifiknitter
RT @LisaRezende1: T4. Many articles on immunotherapy describe "harnessing" the immune system. Some patients describe it as "unleashing." T…
Janet Freeman-Daily @JFreemanDaily
@RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growth accelerates. Pseudo-progression is when the tumor temporarily seems larger because immune system cells are drawn into the tumor and cause inflammation. #LCSM
#LCSM Chat @lcsmchat
@VamsiVelcheti @nyulangone Welcome! #lcsm
Dee Sparacio @womenofteal
RT @JFreemanDaily: @RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growt…
Timothy Craig Allen @TimAllenMDJD
RT @LisaRezende1: T4. I agree hype can be frustrating for patients. It is important to remember we aren't there yet for all cancers or all…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: @RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growt…
KC Dill @kasedill
RT @JFreemanDaily: @RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growt…
Anita Figueras @scifiknitter
RT @JFreemanDaily: @RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growt…
Janet Freeman-Daily @JFreemanDaily
T5: How can I find the right immunotherapy clinical trial for me? #LCSM
Lisa Rezende @LisaRezende1
T4. It is important for patients on immunotherapy to inform any health care provider (such as emergency room providers) that they are on an IO and not traditional chemo. The side effects are different. #LCSM
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T5: How can I find the right immunotherapy clinical trial for me? #LCSM
Janet Freeman-Daily @JFreemanDaily
T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by disease-specific advocacy groups, (3) Cancer Research Institute https://t.co/w5R0ObQtVg #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T5: How can I find the right immunotherapy clinical trial for me? #LCSM
Janet Freeman-Daily @JFreemanDaily
T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy and clinical trials for your cancer #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T4. It is important for patients on immunotherapy to inform any health care provider (such as emergency room providers) t…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
KC Dill @kasedill
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy an…
Janet Freeman-Daily @JFreemanDaily
T5: It’s helpful to discuss trial options with your oncologist, or during a second opinion visit at an academic cancer center that conducts research in your cancer (like an NCI SPORE program -- see https://t.co/9isPR2TclM ) #LCSM
Anita Figueras @scifiknitter
RT @RedGia: @JFreemanDaily T4: #LCSM: Attacks on healthy tissue/glands: I'm now cortisol dependent due to IO therapy damaged pituitary whic…
Lisa Rezende @LisaRezende1
T4. Some groups and companies have developed treatment-specific wallet cards that patients can carry to inform other providers of their treatment and the side effects they can expect. #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy an…
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
JC @stu12bball
@lcsmchat hello all new to the forum. Dad recently diagnosed lung cancer stage IV. He’s PD-L1. Oncologist recommending standard first line treatment. Will consider PD-L1 immunotherapy as second line treatment. Any recommendation from the audience #LCSM
Aparna Hegde, MD @notahedge
RT @JFreemanDaily: T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy an…
Vamsi Velcheti, MD @VamsiVelcheti
@BrendonStilesMD It is still unclear if hyper progression is a real phenomenon.. recent data by @drgandara at @myESMO on the OAK trial showed similar rates of ‘rapid’ progression in chemo and IO arms.. suspect what we are calling hyper progression may just be poor/aggressive biology #LCSM
Aparna Hegde, MD @notahedge
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: T5: It’s helpful to discuss trial options with your oncologist, or during a second opinion visit at an academic cancer c…
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: T5: It’s helpful to discuss trial options with your oncologist, or during a second opinion visit at an academic cancer c…
Dee Sparacio @womenofteal
T5 Could also try the patient recruitment page for the NIH https://t.co/EHCRKc91Vi #lcsm
#LCSM Chat @lcsmchat
RT @LisaRezende1: T4. Some groups and companies have developed treatment-specific wallet cards that patients can carry to inform other prov…
Janet Freeman-Daily @JFreemanDaily
Clinical trial finders recommended by ASCO's https://t.co/bZg1FNdtnK site https://t.co/Z1M9AQ6k9K •Emerging Med https://t.co/UakfAcMNQh •Lazarex Cancer Foundation https://t.co/TCGdlixibj #LCSM
Gia Sonata @RedGia
@JFreemanDaily #LCSM This may sound minor and an "easy fix" (prednisone daily) - but it created 2 lg pericardial effusions because I was in adrenal crisis -w/in two mnths of ea other at diff hospitals. Serious, almost fatal situations. It's why I am dedicated to preaching about baseline labs!
Lecia Sequist, MD, MPH @LeciaSequist
@BrendonStilesMD @BrendonStilesMD the concept of hyperprogression on IO is controversial and some think it doesn't exist. I tend to think that it does and that I've seen it a few times - where IO seems to "unleash" an entirely different tumor behavior #LCSM
Lisa Rezende @LisaRezende1
T5. For those with hereditary cancers, @FacingOurRisk has a clinical trial search tool for hereditary breast, ovarian, prostate, and pancreatic cancers. #LCSM
Dee Sparacio @womenofteal
Yes. Cards especially important for those in clinical trials. #lcsm
Stephen V Liu @StephenVLiu
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
KC Dill @kasedill
RT @JFreemanDaily: T5: It’s helpful to discuss trial options with your oncologist, or during a second opinion visit at an academic cancer c…
#LCSM Chat @lcsmchat
RT @stu12bball: @lcsmchat hello all new to the forum. Dad recently diagnosed lung cancer stage IV. He’s PD-L1. Oncologist recommending s…
Aparna Hegde, MD @notahedge
RT @VamsiVelcheti: @BrendonStilesMD It is still unclear if hyper progression is a real phenomenon.. recent data by @drgandara at @myESMO on…
Lisa Rezende @LisaRezende1
T5. Patients can always talk to their health care team about trials, but unfortunately, the best trial for their cancer might not be available locally. #LCSM
Stephen V Liu @StephenVLiu
@stu12bball @lcsmchat For lung cancer, standard therapy includes immunotherapy as part of initial therapy. Would strongly advise against waiting to implement. Best outsvimes are with first line use. #LCSM
#LCSM Chat @lcsmchat
RT @VamsiVelcheti: @BrendonStilesMD It is still unclear if hyper progression is a real phenomenon.. recent data by @drgandara at @myESMO on…
#LCSM Chat @lcsmchat
RT @womenofteal: T5 Could also try the patient recruitment page for the NIH https://t.co/EHCRKc91Vi #lcsm
KC Dill @kasedill
@JFreemanDaily Bookmarking for future reference. Great info Janet.. #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Clinical trial finders recommended by ASCO's https://t.co/bZg1FNdtnK site https://t.co/Z1M9AQ6k9K •Emerging Med https:/…
Gia Sonata @RedGia
@JFreemanDaily @BrendonStilesMD #LCSM Perfect. Thanks for the explanation.
#LCSM Chat @lcsmchat
RT @RedGia: @JFreemanDaily #LCSM This may sound minor and an "easy fix" (prednisone daily) - but it created 2 lg pericardial effusions beca…
#LCSM Chat @lcsmchat
RT @LeciaSequist: @BrendonStilesMD @BrendonStilesMD the concept of hyperprogression on IO is controversial and some think it doesn't exist.…
#LCSM Chat @lcsmchat
RT @LisaRezende1: T5. For those with hereditary cancers, @FacingOurRisk has a clinical trial search tool for hereditary breast, ovarian, pr…
#LCSM Chat @lcsmchat
RT @StephenVLiu: @stu12bball @lcsmchat For lung cancer, standard therapy includes immunotherapy as part of initial therapy. Would strongly…
Bob Steele @steele_bob
RT @RedGia: @JFreemanDaily #LCSM This may sound minor and an "easy fix" (prednisone daily) - but it created 2 lg pericardial effusions beca…
Gina @EAustin1969
RT @JFreemanDaily: T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy an…
Gia Sonata @RedGia
RT @JFreemanDaily: @RedGia @BrendonStilesMD Hyperprogression and pseudo progression are different. Hyperprogression means the cancer growt…
Dee Sparacio @womenofteal
Very Informative Chat. Thanks @JFreemanDaily for the invite. Looking forward to another joint chat in the summer. Got to run - two dogs need one more walk in the cold and windy outdoors. #lcsm
Janet Freeman-Daily @JFreemanDaily
We’re in our final minutes - closing thoughts? #LCSM
Inspire @teaminspire
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
Anita Figueras @scifiknitter
RT @LisaRezende1: T4. It is important for patients on immunotherapy to inform any health care provider (such as emergency room providers) t…
Stacey Tinianov @coffeemommy
Missed all but the last 2 minutes of the mixed group tweet chat on #Immunotherapy hosted by #LCSM. Now off to a high school music booster meeting but eager to catch up on the tweets later tonight/tomorrow. Hugs all around to the awesome advocates sharing their knowledge 💖
Timothy Craig Allen @TimAllenMDJD
RT @StephenVLiu: @stu12bball @lcsmchat For lung cancer, standard therapy includes immunotherapy as part of initial therapy. Would strongly…
Anita Figueras @scifiknitter
RT @JFreemanDaily: T5: search for I/O clinical trials at (1) NCI database https://t.co/cUZe8RmROH, (2) clinical trial finders offered by…
Aparna Hegde, MD @notahedge
T4 immunotherapy is not benign. Can have severe side effects that are likely more common than what has been reported. Unlike chemo, toxicities can have delayed onset affecting different organs at different time points. #LCSM
Timothy Craig Allen @TimAllenMDJD
RT @JFreemanDaily: Clinical trial finders recommended by ASCO's https://t.co/bZg1FNdtnK site https://t.co/Z1M9AQ6k9K •Emerging Med https:/…
Anita Figueras @scifiknitter
RT @JFreemanDaily: T5: Disease-specific online communities often have knowledgeable advocates who can help you learn about immunotherapy an…
Julia Robertson @Ailuj_Nostrebor
RT @CBlotner_: Pssttt: #btsm #bcsm #lcsm #ayacsm #gyncsm folks - check out this survey to develop a cancer resource for the queer community…
Bob Steele @steele_bob
Would like to see this topic repeated with researcher input. #lcsm
Anita Figueras @scifiknitter
RT @JFreemanDaily: T5: It’s helpful to discuss trial options with your oncologist, or during a second opinion visit at an academic cancer c…
Timothy Craig Allen @TimAllenMDJD
It has been a privilege to participate. #LCSM
Grumpy-ish @marlaceleri
RT @Dollybrad: All you need are lungs and you can get lung cancer. We are not immune to this horrible cancer. Be aware of your body and lis…
Janet Freeman-Daily @JFreemanDaily
Thanks everyone for joining our all-cancer chat about immunotherapy! Hope you found the info helpful. We'll try to get Lisa's slides up later in a post on the https://t.co/39i0y9oxgJ site. #LCSM
KC Dill @kasedill
@JFreemanDaily Always appreciate your moderation and the participants learned a lot tonight.. Good night all #LCSM
SunshineKK @SunshineKK68
Thank you Janet #lcsm
Lisa Rezende @LisaRezende1
T3. Some experts recommend genetic counseling and possibly testing for Lynch syndrome for patients whose tumors have microsatellite instability. If you are concerned that your cancer might be hereditary, a genetic counselor can help you decide if testing is right for you. #LCSM
Bob Steele @steele_bob
Oops. I left out the word "more" researcher input. #lcsm
Christine Qiong Wu @wi_qiong
I'm new for this Tweet, just 2nd time participate, still learning. #lcsm
#LCSM Chat @lcsmchat
RT @JFreemanDaily: We’re in our final minutes - closing thoughts? #LCSM
#LCSM Chat @lcsmchat
RT @notahedge: T4 immunotherapy is not benign. Can have severe side effects that are likely more common than what has been reported. Unlike…
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Thanks everyone for joining our all-cancer chat about immunotherapy! Hope you found the info helpful. We'll try to get…
Janet Freeman-Daily @JFreemanDaily
Thanks to our special guest @LisaRezende1 for bringing her cancer communications skills to the chat! #LCSM
#LCSM Chat @lcsmchat
RT @LisaRezende1: T3. Some experts recommend genetic counseling and possibly testing for Lynch syndrome for patients whose tumors have micr…
Lisa Rezende @LisaRezende1
Thanks for inviting me! #LCSM
Aparna Hegde, MD @notahedge
IO is a great advance for cancer but doesn't benefit everyone. We need to look past the hype and redouble efforts to find predictive markers, better drugs/ drug combinations and address toxicities #LCSM
Betsy @wildwestannie
Thank you Janet, really interesting and nicely explained. #LCSM
Gia Sonata @RedGia
@steele_bob #lcsm YES!
#LCSM Chat @lcsmchat
RT @JFreemanDaily: Thanks to our special guest @LisaRezende1 for bringing her cancer communications skills to the chat! #LCSM
#LCSM Chat @lcsmchat
RT @notahedge: IO is a great advance for cancer but doesn't benefit everyone. We need to look past the hype and redouble efforts to find pr…
Gia Sonata @RedGia
@coffeemommy Have a great evening - be safe and have fun! #lcsm
Anita Figueras @scifiknitter
RT @JFreemanDaily: Clinical trial finders recommended by ASCO's https://t.co/bZg1FNdtnK site https://t.co/Z1M9AQ6k9K •Emerging Med https:/…
Anita Figueras @scifiknitter
RT @RedGia: @JFreemanDaily #LCSM This may sound minor and an "easy fix" (prednisone daily) - but it created 2 lg pericardial effusions beca…
Anita Figueras @scifiknitter
RT @LisaRezende1: T5. For those with hereditary cancers, @FacingOurRisk has a clinical trial search tool for hereditary breast, ovarian, pr…
Cristobal Alvarado @CrisAlvaradoMD
RT @notahedge: @lcsmchat @kasedill It may be so due to a phenomenon called abscopal effect. XRT to 1 lesion may result in shrinkage of othe…
Dr. David Tom Cooke @DavidCookeMD
RT @JFreemanDaily: Thanks everyone for joining our all-cancer chat about immunotherapy! Hope you found the info helpful. We'll try to get…
Bob Steele @steele_bob
Thanks for hosting Janet. Looking forward to the next/every bi-weekly Lung Cancer Social Media Twitter chat session. #lcsm
Aparna Hegde, MD @notahedge
Happy new year everyone. Great chat as always. I enjoyed participating. Thanks for organizing @JFreemanDaily #LCSM
Israh (K.)Akhtar @israhkhan
Immunotherapy emerges as the the lifesaver to these killer cells #lcsm https://t.co/nK50D2SWzn
Bob Steele @steele_bob
RT @israhkhan: Immunotherapy emerges as the the lifesaver to these killer cells #lcsm https://t.co/nK50D2SWzn
KC Dill @kasedill
RT @notahedge: @lcsmchat @kasedill Trials testing this combination are underway. The Pacific trial showed that pts who started durvalumab w…
Anita Figueras @scifiknitter
Thank you @JFreemanDaily and @LisaRezende1 for a very interesting chat. #LCSM
KC Dill @kasedill
@JFreemanDaily “I” learned a lot tonight.. lol thank you Janet and participants.. #LCSM
Gia Sonata @RedGia
@JFreemanDaily Great 2019 kickoff! Well done, as always. Thanks everyone! Happy 2019! #lcsm And please - before IO talk to your onc about baseline labs for thyroid (more than just tsh) and pituitary/adrenal (cortisol, acth) . Talk to an endocrinologist familiar with IO. I wish I went sooner!
Janet Freeman-Daily @JFreemanDaily
@RedGia So sorry you developed thyroid issues after immunotherapy. Hope steroids and other treatments are helping with that. #LCSM
Janet Freeman-Daily @JFreemanDaily
@wi_qiong Glad you were able to join. We learn by doing! #LCSM
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