#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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See #NephJC Influencers/Analytics.

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Sharon Lagas @SharonLagas
RT @gratefull080504: Here are the @goKDIGO guidelines for #raredisease #kidneydisease @IGANFoundation @PKDFoundation @Nephcure #nephJC @AlportSyndFndn https://t.co/4BV567wHX6
CAPN-ANPC @CAPNeph
RT @NephJC: Fluid Resuscitation in Sepsis: Fluid Resuscitation in Sepsis: The next #NephJC summary https://t.co/l5X80arQ9F
Daniel Amador (IM, Neph) @DanielAmador_dr
RT @kidney_boy: Here is a #VisualAbstract (kind of) that describes Simplified Severe Sepsis Protocol (SSSP) that failed in the study. Don't do this! #NephJC https://t.co/emjepMVAG8
LifEnrich @LifEnrichLLC
RT @hswapnil: Paul Marik opines on the Andrews et al trial we are discussing tomorrow at #NephJC https://t.co/t5NDodZ4QD on @emcrit h/t @medevidenceblog
Arvind Canchi (Conjeevaram)🇮🇳 @arvindcanchi
Nice summary by @Errantnephron on the next #nephjc topic. Fluid Resus in Sepsis - Another Failure. https://t.co/uZ8xtiATUr
@askrenal @askrenal
.@nephjc RT @rednephron: Salient H&I slides from UCL transplant course #NephJC #askrenal https://t.co/0vokCax98q
@askrenal @askrenal
.@nephjc RT @rednephron: Anaesthetic assessment of pulmonary hypertension in the pre-tx work up. #NephJC #askrenal https://t.co/TQQVfMzB5I
@askrenal @askrenal
.@nephjc RT @rednephron: Really important slide - immunological pre-tx risk assessment. #askrenal #NephJC https://t.co/4HpUBWJgvU
Nephrology Journal Club @NephJC
Join us tonight to discuss a RCT of sepsis treatment. 9pm EST #NephJC https://t.co/cySCXGpFjZ
Sibel Gokcay Bek @sibgokcay
RT @askrenal: .@nephjc RT @rednephron: .@nephjc RT @rednephron: Anaesthetic assessment of pulmonary hypertension in the pre-tx work up. #NephJC #askrenal https://t.co/TQQVfMzB5I
Nephrology Journal Club @NephJC
Sepsis in Africa Visual Abstract https://t.co/Ng76OMPFwR
Cristhy Albornoz @acristhy
RT @NephJC: Fluid Resuscitation in Sepsis: Fluid Resuscitation in Sepsis: The next #NephJC summary https://t.co/l5X80arQ9F
ISN Education @ISNeducation
@DamianFog :) Send us your 2018 campaign and we'll list it in the re-designed Directory...releases December 2017 #NephEd #NephJC
Ana Maria Matias @AMCMA6
RT @askrenal: .@nephjc RT @rednephron: .@nephjc RT @rednephron: Anaesthetic assessment of pulmonary hypertension in the pre-tx work up. #NephJC #askrenal https://t.co/TQQVfMzB5I
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Join us tonight to discuss a RCT of sepsis treatment. 9pm EST #NephJC https://t.co/cySCXGpFjZ
Ana Maria Matias @AMCMA6
RT @NephJC: Join us tonight to discuss a RCT of sepsis treatment. 9pm EST #NephJC https://t.co/cySCXGpFjZ
Mana @manasigh
RT @kidney_boy: #VisualAbstract Release Candidate 1 for tomorrow's #NephJC on Protocol Driven Sepsis Therapy in Africa. Looking For Feedback. Be brutal. https://t.co/Hj9DyngKlc
Sibel Gokcay Bek @sibgokcay
RT @NephJC: Sepsis in Africa Visual Abstract https://t.co/Ng76OMPFwR
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Sepsis in Africa Visual Abstract https://t.co/Ng76OMPFwR
Sibel Gokcay Bek @sibgokcay
RT @kidney_boy: Here is a #VisualAbstract (kind of) that describes Simplified Severe Sepsis Protocol (SSSP) that failed in the study. Don't do this! #NephJC https://t.co/emjepMVAG8
Nephrology Journal Club @NephJC
RT @NephJC: Join us tonight to discuss a RCT of sepsis treatment. 9pm EST #NephJC https://t.co/cySCXGpFjZ
Nephrology Journal Club @NephJC
RT @NephJC: Sepsis in Africa Visual Abstract https://t.co/Ng76OMPFwR
Nephrology Journal Club @NephJC
#NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Joel M. Topf, MD FACP @kidney_boy
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Bea Concepcion @KidneyBea_n
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Rolando Claure, MD, FASN, FISN 🇧🇴 @RClaure_nefro
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
soda_troubles,https://med-mastodon.com/@haysam @set_fortess
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Gonzalo Bautista Prieto. MD 🇪🇨 @GonzalBautistaP
RT @kidney_boy: #VisualAbstract Release Candidate 1 for tomorrow's #NephJC on Protocol Driven Sepsis Therapy in Africa. Looking For Feedback. Be brutal. https://t.co/Hj9DyngKlc
Silvi Shah, MD, MS @silvishah
RT @NephJC: Sepsis in Africa Visual Abstract https://t.co/Ng76OMPFwR
devika nair md msci @devimol
sad to miss #NephJC - am a paul marik fan. many qs - usual care got ~earlier abx. 4L = a lot in ppl who are fluid avid+chronically-inflamed
Nephrology Journal Club @NephJC
Testing 1,2,3. #nephjc
Nephrology Journal Club @NephJC
We are live and ready to rock! #nephjc
Nephrology Journal Club @NephJC
Going to run and pour a glass scotch, don't start with out me #nephjc
Nephrology Journal Club @NephJC
It’s 9 PM Tuesday. Welcome to another exciting edition of #NephJC
Nephrology Journal Club @NephJC
I'm Joel Topf, co-founder of #NephJC. I'll be spinning the freshest Tweets from HDub https://t.co/qORqQgbyaG #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC The right fluid to discuss the fluid trial, eh Joel? #NephJC
Nephrology Journal Club @NephJC
Anybody out there? Or did I put in the wrong hashtag on TChat? #nephjc
Nephrology Journal Club @NephJC
Hey Swap, thanks for coming. #nephjc
Roger Rodby @NephRodby
Roger Rodby, love scotch but recently prefer Manhattans #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Swapnil Hiremath from @OttawaHospital #nephjc No CoI Restrictive fluid user? https://t.co/AQbhmjNYkw
Nephrology Journal Club @NephJC
Remember to add #NephJC to every tweet. That will allow everybody in the chat to see your contribution.
Nephrology Journal Club @NephJC
Hey Rodger, did the Cubs beat the Nats? #nephjc
Roger Rodby @NephRodby
Rained out today #nephjc
Nephrology Journal Club @NephJC
I am a clinical nephrologist. I have no conflicts of interest (COI). #NephJC
Annabel Biruete 🇲🇽 @anniebelch
Annabel Biruete, dietetic intern @BSUHealth and #NSMC intern. Lurking tonight🙊 #NephJC
Nephrology Journal Club @NephJC
Please share your name, and COI. #nephjc
Nephrology Journal Club @NephJC
We recommend using tchat.io or https://t.co/rFoH4MVMzu. They filter out everything but the hashtag and add #NephJC to every tweet
Nephrology Journal Club @NephJC
Hey Annabel, you coming to New Orleans? #nephjc
Michelle Rheault @rheault_m
@NephJC Michelle here. Ped Neph. COI in bio. Never been to Zambia. #NephJC
Nephrology Journal Club @NephJC
Ankit, thanks for coming! #nephjc
Nephrology Journal Club @NephJC
Michelle! Great! #nephjc
Matthew Sparks, MD @Nephro_Sparks
Matt Sparks #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@anniebelch @BSUHealth hey Annabel! #NSMC represent! #nephjc
Nephrology Journal Club @NephJC
One of the goals of #NephJC is to build a personal learning network, so punch that follow button https://t.co/WTusn7Yx2W
Silvi Shah, MD, MS @silvishah
Hi this is Silvi transplant nephrologist #nephJC no Coi
Nephrology Journal Club @NephJC
Hey Matt, thanks for making it. #nephjc
Nephrology Journal Club @NephJC
Silvi! #nephjc
Nephrology Journal Club @NephJC
Give a shout out when you push it and push it real good https://t.co/wxSJjm8YlZ #NephJC
Pravir @Proximal_Baxi
Pravir Baxi, Rush Nephrology, no COI #nephjc
Gates Colbert, MD @DoctorGates
Dallas Nephrologist. #NSMC 2017. COI: I take care of a LOT of ICU patients, sometimes with Na 180. Think fluid first, then wait/resist the bolus/track your I/O. #NephJC
Nephrology Journal Club @NephJC
@rheault_m You predicted the topic zero question! #nephjc
Nephrology Journal Club @NephJC
While we are waiting, Topic Zero: Have you been to Africa? Zambia? Have you been a doctor or nurse in Africa? #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@ansakhuja ooh! Critical care trained: just what we need tonight! #nephjc
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
Hi everyone. Hector Madariaga. From #Patriotsnation. No COI #nephjc
Nephrology Journal Club @NephJC
Pravir, thanks for coming. We interviewed one of your residents for our fellowship last week! #nephjc
Silvi Shah, MD, MS @silvishah
@NephJC No never..would like to go though #NephJC
Annabel Biruete 🇲🇽 @anniebelch
@NephJC Of course! Can't wait for #kidneywk and and the #NephJC #tweetup!
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@Proximal_Baxi hey Pravir! Thanks for coming tonight #nephjc
Roger Rodby @NephRodby
I've seen the Lion King on broadway, is that a COI? #nephjc
Nephrology Journal Club @NephJC
Roger being Roger! RT @NephRodby: I've seen the Lion King on broadway, is that a COI? #nephjc
Nephrology Journal Club @NephJC
@NephRodby you're like the Puig of #NephJC
Nephrology Journal Club @NephJC
Alternate Topic Zero. If Doc Rivers' Early Goal Directed Therapy was on Tinder, would you swipe left or right? #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Edgar Lerma, 🌧 Chicago-based Nephrologist #NephJC https://t.co/1NawWghiRv
Roger Rodby @NephRodby
RT @NephJC: @NephRodby you're like the Puig of #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@DoctorGates Awesome! Let's see some #280character tweets tonight! #nephjc
Bea Concepcion @KidneyBea_n
Bea Concepcion @VUMCKidney, Nashville TN, no COI #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: While we are waiting, Topic Zero: While we are waiting, Topic Zero: Have you been to Africa? Zambia? Have you been a doctor or nurse in Africa? #NephJC
Michelle Rheault @rheault_m
@NephJC I worked at an orphanage in rural Romania once. Pretty awful and low resource in its own way. #NephJC
Nephrology Journal Club @NephJC
Wow, sounds hard RT @rheault_m:I worked at an orphanage in rural Romania once. Pretty awful and low resource in its own way. #NephJC
Nephrology Journal Club @NephJC
Hey Bea, thanks for coming #nephjc
Matthew Sparks, MD @Nephro_Sparks
@KidneyBea_n @VUMCKidney Hi Bea #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
T0: no, not been to Africa or Tinder. #gulp #nephjc
Roger Rodby @NephRodby
RT @NephJC @NephRodby you're like the Puig of #NephJC The Puig of NephJC: all hype, overrated, egomaniac? Yikes
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
@NephJC never. Been a doctor in rural areas, though #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@KidneyBea_n @VUMCKidney Hi Bea! Good #NSMC presence tonight with @anniebelch & @DoctorGates #nephJC
Silvi Shah, MD, MS @silvishah
@anniebelch @BSUHealth Hi Anna! #nephjc
Nephrology Journal Club @NephJC
@edgarvlermamd did you ever practice medicine in the Philippines? #nephjc
Matthew Sparks, MD @Nephro_Sparks
@NephJC GDT was preached and meticulously followed when I was in ICU as resident #NephJC I drank the KoolAid
Pravir @Proximal_Baxi
@hswapnil thanks! too much rain and too late to golf ;) JK #nephjc
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
@anniebelch see you there! 😃 @NephJC #nephjc
Nephrology Journal Club @NephJC
with low resources? What was it like? RT @HecmagsMD: @NephJC never. Been a doctor in rural areas, though #nephjc
Matthew Sparks, MD @Nephro_Sparks
@NephJC Not sure which way the swipe is good #NephJC is it like clearing notification on EMR
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Early Resuscitation Protocol ➡️ In-hospital Mortality in Adults w/ Sepsis & Hypotension 🇿🇲 #NephJC #Nephpearls 👉🏼 https://t.co/C3GbN47L3M https://t.co/64yqVCHUnr
Nephrology Journal Club @NephJC
Had an opportunity to go to Kenya as a resident. Foolishly didn't do it. Big mistake. One of my few regrets. #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
Though working at public hospital in Mumbai was pretty resource poor. Lots of malaria and other infectious septic shock...#nephjc
Gates Colbert, MD @DoctorGates
TO: Tonights chat theme song: https://t.co/XwYSFsDdWf #NephJC
Nephrology Journal Club @NephJC
@Nephro_Sparks we're so old we won't admit to knowing how to use Tinder #nephjc
Roger Rodby @NephRodby
One of my partners Casey Gashti went to Haiti and volunteered, so limited in what he had to offer #nephjc
Nephrology Journal Club @NephJC
@DoctorGates I was thinking of using that for the title of the post #nephjc
Nephrology Journal Club @NephJC
RT @NephRodby: One of my partners Casey Gashti went to Haiti and volunteered, so limited in what he had to offer #nephjc
Matthew Sparks, MD @Nephro_Sparks
@Proximal_Baxi @hswapnil #MorningGolfGate #NephJC #RenalRushAttendingsGolfInsteadOfRound
Michelle Rheault @rheault_m
@NephJC @Nephro_Sparks I tell my husband I keep him around just so I don't have to learn how to use a new dating app. #NephJC
Nephrology Journal Club @NephJC
28-day mortality and time to death #nephjc
Nephrology Journal Club @NephJC
This is a single center, open label, randomized controlled trial of a sepsis protocol versus usual care. This was done in Zambia #NephJC
Nephrology Journal Club @NephJC
The burden of sepsis is greatest in developing countries but what we know about sepsis comes from wealthy countries. #NephJC
Nephrology Journal Club @NephJC
Do you think we should to apply the lessons of wealthy countries to developing countries? #NephJC
Silvi Shah, MD, MS @silvishah
@NephJC @HecmagsMD Have practiced medicine with low resources ... not that easy #nephjc
Bea Concepcion @KidneyBea_n
Victoria Falls in 2016 #NephJC https://t.co/vDTtRxjqbv
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: Do you think we should to apply the lessons of wealthy countries to developing countries? #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: The burden of sepsis is greatest in developing countries but what we know about sepsis comes from wealthy countries. #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@NephJC I came to the US 🇺🇸 right after graduation from @UST1611official @ustmaa #NephJC https://t.co/XgTqKQEzFk
Roger Rodby @NephRodby
The most limited I have ever been was moonlighting as a resident in a rural VA #nephjc
Scherly Leon, MD @SLeonMD
#nephjc Hello all! Scherly, nephrologist in NYC. Schedule conflicts with chats now. Joining on phone.
Annabel Biruete 🇲🇽 @anniebelch
RT @NephJC: The burden of sepsis is greatest in developing countries but what we know about sepsis comes from wealthy countries. #NephJC
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
Yes.Small outpatient clinic & limited resources including meds & diagnostic tests(almost non existent) Best resource was education #nephJC https://t.co/085abL5VA9
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC Etiology, patient profile different , but arguably pathogenesis, similar in septic shock? #nephjc
Nephrology Journal Club @NephJC
RT @edgarvlermamd: Edgar Lerma, 🌧 Chicago-based Nephrologist #NephJC https://t.co/1NawWghiRv
Cathy Quinlan @CathyQuinlan.bsky.social @KidneyCathy
Lurking today but learning loads. #NephJC
Roger Rodby @NephRodby
@hswapnil @NephJC sepsis is sepsis, must be, after all we evolved from Africa #nephjc
Nephrology Journal Club @NephJC
@SLeonMD You are missed! Do your best! Any developing country medical stories to share? #nephjc
Pravir @Proximal_Baxi
@hswapnil @NephJC thats what I would think as well #nephjc
Nephrology Journal Club @NephJC
The visual abstract for the study: https://t.co/Ng76OMPFwR #NephJC
Gates Colbert, MD @DoctorGates
@NephJC I think we have to trust the data we are given. Obviously we welcome publishing from resource poor settings. Look at Mesoamerican Nephropathy in Central America - hotspot of CKDu. Limited resources, wealth of data/insight/knowledge/hope. #280toolong? #NephJC
Nephrology Journal Club @NephJC
Topic One: Methods | What they did #nephjc
Nephrology Journal Club @NephJC
Study ran from Oct 2012 to November 2013. #NephJC
Nephrology Journal Club @NephJC
Inclusion criteria: 1. Sepsis (suspected infection + ≥ 2 SIRS syndrome criteria) #NephJC
Nephrology Journal Club @NephJC
Inclusion criteria: 2. and hypotension (SBP ≤90 or MAP ≤ 65) #NephJC
Nephrology Journal Club @NephJC
Exclusion Criteria: Hypoxia O2 sat < 90% or RR > 40 #NephJC
Nephrology Journal Club @NephJC
When NephJC gets 280 characters that will be easier #nephjc
Scherly Leon, MD @SLeonMD
Yes. Worked in Haiti after residency for short while and did trip to Peru in medical school. #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC Yes and No! What is efficacious may not be effective (eg processes)? #NephJC https://t.co/XCMelRbR2X
Nephrology Journal Club @NephJC
Additional exclusion criteria: GI bleed without fever, CHF exacerbation, ESRD, elevated JVP, need for immediate surgery. #NephJC
Nephrology Journal Club @NephJC
Inclusion and Exclusion seem kosher? What's there that is surprising? What's missing? #NephJC
Roger Rodby @NephRodby
important that these are savageble sepsis patients #nephjc
Scherly Leon, MD @SLeonMD
RT @NephJC: The visual abstract for the study: The visual abstract for the study: https://t.co/Ng76OMPFwR #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: The visual abstract for the study: The visual abstract for the study: https://t.co/Ng76OMPFwR #NephJC
Nephrology Journal Club @NephJC
@NephRodby that's hard to know prospectively #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: @hswapnil @NephJC sepsis is sepsis, must be, after all we evolved from Africa #nephjc
Nephrology Journal Club @NephJC
@ansakhuja can we also add ARISE to that group of failed EGDT studies? #nephjc
Matthew Sparks, MD @Nephro_Sparks
RT @HecmagsMD: Yes.Small outpatient clinic & limited resources including meds & diagnostic tests(almost non existent) Best resource was education #nephJC https://t.co/085abL5VA9
Nephrology Journal Club @NephJC
I guess GI bleed and fever in Africa means viral hemorrhagic fever? Frightening if so. #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC Is it too early to ask why it took 4 years to publish? #NephJC #skeptic
Bea Concepcion @KidneyBea_n
RT @NephJC: The visual abstract for the study: The visual abstract for the study: https://t.co/Ng76OMPFwR #NephJC
Hector Madariaga, MD FASN 🇲🇽 @HecmagsMD
RT @NephRodby: @hswapnil @NephJC sepsis is sepsis, must be, after all we evolved from Africa #nephjc
Roger Rodby @NephRodby
@NephJC yes but it seems that these were treated early enough to make a difference and actually study an effect of fluid #nephjc
Nephrology Journal Club @NephJC
Great work on enrolling patients within 4 hours of first BP measurement. #NephJC
Roger Rodby @NephRodby
@hswapnil @NephJC yes the elephant in the room #nephjc
Roger Rodby @NephRodby
RT @NephRodby @hswapnil @NephJC yes the elephant in the room #nephjc (no pun intended)
Nephrology Journal Club @NephJC
@hswapnil @NephJC yes too early #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@ansakhuja @NephJC Good points - but these were all legit practices in 2012 I presume? #NephJC
Gates Colbert, MD @DoctorGates
T1: Amazing that almost half had HIV. Striking. #NephJC
Nephrology Journal Club @NephJC
I thought it was 90% RT @DoctorGates: T1: Amazing that almost half had HIV. Striking. #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@NephJC Not this Doc Rivers #NephJC https://t.co/VmtjCMB74e
Nephrology Journal Club @NephJC
#NephJC HIV is everywhere https://t.co/qgJQ460qTp
Roger Rodby @NephRodby
What is used or preferred these days, SOFA, Apache, other? #nephjc
Gates Colbert, MD @DoctorGates
Yes my error, 90+ #NephJC
Nephrology Journal Club @NephJC
@edgarvlermamd or this one #NephJC https://t.co/PXEDfIqcfS
Annabel Biruete 🇲🇽 @anniebelch
@NephRodby When I did my first internship in 🇲🇽 it was Apache, now my internship here (5y later) I feel the ICU doctors mention mostly SOFA #NephJC
Nephrology Journal Club @NephJC
I can't find average weights for patients, anyone? MT @ansakhuja: 30cc/kg fluid is now recommended for sepsis #nephjc
Nephrology Journal Club @NephJC
People that did outcome assessments were blinded to the treatment group. #NephJC
Matthew Sparks, MD @Nephro_Sparks
I'm back #nephjc
Nephrology Journal Club @NephJC
Patients, treating clinicians, and clinical study personnel were aware of group assignment after enrollment. #NephJC Good
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Rivers’ Early Goal Directed Therapy EGDT Criteria #Nephpearls #NephJC https://t.co/cnKsLOmQNg
Gates Colbert, MD @DoctorGates
Anybody using the straight leg raise with CVP monitoring to assess fluid status? #NephJC
Nephrology Journal Club @NephJC
@ansakhuja @NephJC mean upper arm circumference, MUAC. It has its own Wikipedia page #nephjc
Pablo Garcia @PabloGarciaMD
#NephJC Pablo Garcia. Intern NSMC 2017. No CoI. Today from Guatemala. https://t.co/IjplNoYdP6
Nephrology Journal Club @NephJC
RT @DoctorGates: Anybody using the straight leg raise with CVP monitoring to assess fluid status? #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@ansakhuja which is perhaps acceptable for setting? Can't do something in RCT which cant translate to real life? #nephjc
Nephrology Journal Club @NephJC
OMG that is awesome! #Jelous #NephJC https://t.co/sUCPzRMpMj
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@PabloGarciaMD nice! #nephjc
Nephrology Journal Club @NephJC
There are only 10 ICU beds in all of Zambia! RT @ansakhuja: And only 1 of 209 patients was admitted in ICU. These were sick patients #nephjc
Nephrology Journal Club @NephJC
The treatment group received the Simplified Severe Sepsis Protocol (SSSP). See the 2nd visual abstract at: https://t.co/8MWxflxXn5 #NephJC
Nephrology Journal Club @NephJC
SSSP patients got 2 liters in 1 hour then 2 more liters in the next 4 hours. Dopamine is MAP <65 and transfusions for Hgb <7 #NephJC
Nephrology Journal Club @NephJC
Higher than placebo? RT @ansakhuja: Dopamine was the only pressor available, it is associated with higher mortality in septic shock #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
ProCESS Trial vs Rivers EGDT #Nephpearls #NephJC 👉🏼 https://t.co/pD3lEMisIH https://t.co/mVIDhYoSxJ
Michelle Rheault @rheault_m
RT @NephJC: The treatment group received the Simplified Severe Sepsis Protocol (SSSP). See the 2nd visual abstract at: The treatment group received the Simplified Severe Sepsis Protocol (SSSP). See the 2nd visual abstract at: https://t.co/8MWxflxXn5 #NephJC
Bea Concepcion @KidneyBea_n
RT @NephJC: There are only 10 ICU beds in all of Zambia! RT @ansakhuja: There are only 10 ICU beds in all of Zambia! RT @ansakhuja: And only 1 of 209 patients was admitted in ICU. These were sick patients #nephjc
Nephrology Journal Club @NephJC
I'm not certain but I'm guessing it was Dopamine or nothing. #nephjc
Nephrology Journal Club @NephJC
In the SSSP patients were screened for fluid overload every hour. Fluids were stopped if O2 sat fell 3%, Resp rate inc'd 5bpm, or... #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@DoctorGates do we even really know distance from sternal angle to RA? https://t.co/OgVz9k8l0U #nephjc
Matthew Sparks, MD @Nephro_Sparks
@NephJC Dopamine all they have in these settings? #nephjc
Roger Rodby @NephRodby
Is dopamine kosher these days? Has it been shown to be harmful in any way? #nephjc
Nephrology Journal Club @NephJC
cont: In the SSSP patients were screened for fluid overload every hour. Fluids were stopped if JVP >3 CM over sternal notch #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@ansakhuja @NephJC and fallen out of favour pre-2012, am i right? #nephjc
Adam Cifu @adamcifu
RT @edgarvlermamd: Edgar Lerma, 🌧 Chicago-based Nephrologist #NephJC https://t.co/1NawWghiRv
Nephrology Journal Club @NephJC
The Spice girls have fallen out of favor. Has dopamine simple fallen out of favor or rigorously shown to be inferior? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@ansakhuja again - these don't limit internal validity - but do make generalizability tough? #nephjc
Nephrology Journal Club @NephJC
What do you think of these stopping criteria? If a resident used them while assessing patients, I would nod my head #NephJC
Silvi Shah, MD, MS @silvishah
@ansakhuja Any idea what is the difference in mortality between dopamine and levophed? #nephJC
Roger Rodby @NephRodby
I remember the days of "renal dose dopamine", damn I'm old #nephjc
Pravir @Proximal_Baxi
@NephJC I heard a reunion is on though.... #nephjc
Nephrology Journal Club @NephJC
The usual care group got < 2 liters of fluid in the first 6 hours and less than half received anu fluid bolus at all. #NephJC
Matthew Sparks, MD @Nephro_Sparks
andreoli would do it all the time... CRs job to stop it RT @NephRodby: I remember the days of "renal dose dopamine", damn I'm old #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@NephJC Amen to that! But would like to know @ansakhuja thoughts? #nephjc
Nephrology Journal Club @NephJC
No boluses? That just doesn't sound like sepsis #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
Primary outcome was in-hospital mortality #nephjc
Nephrology Journal Club @NephJC
Secondary outcome: 28-day mortality and time to death #nephjc
Nathaniel Reisinger @nephrothaniel
RT @NephJC: The visual abstract for the study: The visual abstract for the study: https://t.co/Ng76OMPFwR #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: There are only 10 ICU beds in all of Zambia! RT @ansakhuja: There are only 10 ICU beds in all of Zambia! RT @ansakhuja: And only 1 of 209 patients was admitted in ICU. These were sick patients #nephjc
Matthew Sparks, MD @Nephro_Sparks
Critical Care Region #NephMadness 2015 #NephJC https://t.co/3AUBOCz6qb
Nephrology Journal Club @NephJC
Are we okay with the outcomes? Any further questions on the methods? (yes, I know you have moved on but I have a script, kind of) #nephjc
Matthew Sparks, MD @Nephro_Sparks
@ansakhuja @hswapnil @NephJC why the difference in groups #askingforafriend #nephjc
Gates Colbert, MD @DoctorGates
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Matthew Sparks, MD @Nephro_Sparks
lol RT @NephJC: I know you have moved on but I have a script, kind of) #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@Nephro_Sparks @NephJC If not in ICU, can't monitor BP closely/intensively, hard to titrate pressors IMO #NephJC
Nephrology Journal Club @NephJC
Topic Two: RESULTS #nephjc
Nephrology Journal Club @NephJC
"Of 382 pts w/ sepsis & hypotension, 212 met eligibility criteria, provided consent to participate, & were randomized" INCREDIBLE #NephJC
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@srrezaie ✅ The myth of renal dose dopamine #RenalRules #Nephpearls #NephJC 👉🏼 https://t.co/xHHgHoiG2Q https://t.co/39AoW7Z9Fj
Nephrology Journal Club @NephJC
If you have ever enrolled ICU patients in an RCT you know how incredible that last stat is! #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
Hats off to the investigators and people of Zambia #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: "Of 382 pts w/ sepsis & hypotension, 212 met eligibility criteria, provided consent to participate, & were randomized" INCREDIBLE #NephJC
Roger Rodby @NephRodby
Zambia, Zambia, serious kudos! #nephjc
Nephrology Journal Club @NephJC
@ansakhuja @Nephro_Sparks @hswapnil @NephJC I'm guessing they were white a bit smaller than 80 kg. Mean MUAC was 20 cm! #nephjc
Matthew Sparks, MD @Nephro_Sparks
@ansakhuja @hswapnil @NephJC so it is the resus technique then?? confused #NephJC
Silvi Shah, MD, MS @silvishah
@NephJC Yes- kudos to them #NephJC
Pablo Garcia @PabloGarciaMD
RT @NephJC: Hats off to the investigators and people of Zambia #nephjc
Nephrology Journal Club @NephJC
I love me some Table 1! #NephJC https://t.co/zGBSQI0drS
Nephrology Journal Club @NephJC
Undertand RT @ansakhuja: @NephJC @Nephro_Sparks @hswapnil I was being generous 🤓#nephjc #nephjc
Silvi Shah, MD, MS @silvishah
@NephJC P values would have helped...#nephJC
Roger Rodby @NephRodby
@NephJC Lactate 4-5, speaks volumes (another no pun intended) #nephjc
Nephrology Journal Club @NephJC
@ansakhuja is making a bid for #NephJC MVP in this chat alone. Incredible tweeting!
Bea Concepcion @KidneyBea_n
RT @Nephro_Sparks: @ansakhuja @hswapnil @NephJC so it is the resus technique then?? confused #NephJC
Pablo Garcia @PabloGarciaMD
I agree, to conduct a trial like that in low income country requires a lot of effort https://t.co/xPrNIPe13x
Matthew Sparks, MD @Nephro_Sparks
so standard arm just gave Abx & stood and watched & had better outcomes. the other was killed with dopamine and fluids. hmmph #nephjc
Nephrology Journal Club @NephJC
Average age was 36.7. That sounds like babies. What were the average age in Process, ARISE and PROMISE? #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: I love me some Table 1! #NephJC https://t.co/zGBSQI0drS
Gates Colbert, MD @DoctorGates
@NephRodby @NephJC Yet so few made it to an ICU bed bc lack of resources #NephJC
Nephrology Journal Club @NephJC
@Nephro_Sparks Not so disimilar to FEAST trial where boluses of albumin or saline were equal and worse than no bolus at all. #nephjc
Annabel Biruete 🇲🇽 @anniebelch
@NephJC I didn't read the paper, but odd they reported MUAC and not other anthropometric measurement (e.g., wt, ht, BMI) #NephJC
Bea Concepcion @KidneyBea_n
real world setting in many parts of the world RT @ansakhuja: @Nephro_Sparks @hswapnil @NephJC and septic shock patients on floor #nephjc
Nephrology Journal Club @NephJC
@DoctorGates @NephRodby @NephJC When there are 10 ICU beds in the whole country, everyone but the president is treated on the floor #nephjc
Gates Colbert, MD @DoctorGates
@Nephro_Sparks Ever read House of God?? #FatMan #NephJC
Nephrology Journal Club @NephJC
RT @anniebelch: @NephJC I didn't read the paper, but odd they reported MUAC and not other anthropometric measurement (e.g., wt, ht, BMI) #NephJC
Roger Rodby @NephRodby
Call me naive, call me in denial, but I just don't see these methods issues as that big a deal since otherwise is simple study #nephjc
Matthew Sparks, MD @Nephro_Sparks
truf RT @KidneyBea_n: real world setting in many parts of the world RT @ansakhuja: and septic shock patients on floor #nephjc
Matthew Sparks, MD @Nephro_Sparks
@ansakhuja @Nephro_Sparks maybe need less ICU #nephjc
Nephrology Journal Club @NephJC
SICK PEOPLE: Median SBP was 83 mmHg (IQR, 76-87 mm Hg) with a median lactate level of 4.3 mmol/L (IQR, 2.8-7.7 mmol/L). #nephjc
Matthew Sparks, MD @Nephro_Sparks
seems like the more we throw at them the worse they do... maybe NE and the other "pressors" just as bad #nephjc
Pablo Garcia @PabloGarciaMD
#NephJC 1. All the sepsis trials were conducted in high income countries. The guidelines are made for high income countries.
Nephrology Journal Club @NephJC
20% had positive tuberculosis blood cultures. I don't think I have ever seen a blood culture positive for TB #nephjc
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: Call me naive, call me in denial, but I just don't see these methods issues as that big a deal since otherwise is simple study #nephjc
Michelle Rheault @rheault_m
RT @PabloGarciaMD: #NephJC 1. All the sepsis trials were conducted in high income countries. The guidelines are made for high income countries.
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @KidneyBea_n: real world setting in many parts of the world RT @ansakhuja: real world setting in many parts of the world RT @ansakhuja: @Nephro_Sparks @hswapnil @NephJC and septic shock patients on floor #nephjc
Pablo Garcia @PabloGarciaMD
#NephJC 2. This is a very important trial for low income countries. Like Guatemala for example.
Salim R. Rezaie, MD @srrezaie
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Matthew Sparks, MD @Nephro_Sparks
RT @PabloGarciaMD: #NephJC 2. This is a very important trial for low income countries. Like Guatemala for example.
Roger Rodby @NephRodby
@PabloGarciaMD Important trial for much of the world #nephjc
Pablo Garcia @PabloGarciaMD
#NephJC 3. Here in Guatemala sometimes we don't have dopamine available.
Annabel Biruete 🇲🇽 @anniebelch
@Nephro_Sparks What about simple stuff like Vitamin C and Thiamine? https://t.co/uTRstxzRBX #NephJC
Matthew Sparks, MD @Nephro_Sparks
way ahead of the curve RT @PabloGarciaMD: #NephJC 3. Here in Guatemala sometimes we don't have dopamine available.
Edgar V. Lerma 🇵🇭 @edgarvlermamd
Comparison of Rivers, ProMISe, ProCESS, ARISE studies #Nephpearls #NephJC https://t.co/xxT9xTVHq0
Pablo Garcia @PabloGarciaMD
#NephJC 4. With trials like this I can say "let's use dopamine instead of norepinephrine because it showed less mortality"
Matthew Sparks, MD @Nephro_Sparks
NOOOOOO RT @anniebelch: @Nephro_Sparks What about simple stuff like Vitamin C and Thiamine? https://t.co/gsM7PUT7P3 #NephJC
Matthew Sparks, MD @Nephro_Sparks
@anniebelch @Nephro_Sparks no offense but talk about poorly conducted study.. retrospectoscopy before and after (NOT GOOD)... #nephjc
Anupam Singh @anupampom
@NephJC Anupam Singh , hospitalist, India ,no COI #nephjc
Annabel Biruete 🇲🇽 @anniebelch
@Nephro_Sparks The intensivists and pharmacist were implementing in the hospital I rotated 😳#NephJC
Nephrology Journal Club @NephJC
median time between ED registration and the first dose of intravenous antimicrobial therapy was similar in both groups #nephjc
Michelle Rheault @rheault_m
RT @edgarvlermamd: Comparison of Rivers, ProMISe, ProCESS, ARISE studies #Nephpearls #NephJC https://t.co/xxT9xTVHq0
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@tulunsokit @NephJC Hey Tulun! #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@ansakhuja Comparison of Rivers, ProMISe, ProCESS, ARISE studies #Nephpearls #NephJC https://t.co/YW59P9zlaB
Nephrology Journal Club @NephJC
Only 11 minutes left, sorry guys. But top line: 48% with protocol, 33% when docs used their brain. The brain wins! #nephjc
Roger Rodby @NephRodby
Not a small difference in mortality. #nephjc
Anupam Singh @anupampom
@Nephro_Sparks @PabloGarciaMD Dopamine has higher mortality than noepi..#nephjc https://t.co/A1vWT0gIGL
Matthew Sparks, MD @Nephro_Sparks
@PabloGarciaMD but Dopamine was used in group with more mortality in this study #nephjc
Nephrology Journal Club @NephJC
When people know little protocols are good, when we get better at sepsis, brains are individual assessment wins #nephjc
Matthew Sparks, MD @Nephro_Sparks
clear as mud RT @ansakhuja: @tulunsokit @edgarvlermamd we know that some fluid is beneficial, what 'some' is, is unclear #nephjc
Nephrology Journal Club @NephJC
The Number Needed to Harm in this patient is astounding: 6 for in-hospital mortality and 4 for 28-day mortality #nephjc
Roger Rodby @NephRodby
Is some fluid beneficial or too little detrimental? #nephjc
Roger Rodby @NephRodby
@NephJC that is a remarkable statistic #nephjc
Nephrology Journal Club @NephJC
@NephRodby In FEAST the control group got "maintenance fluids" and did better than boluses (20 ml/kg I think) #nephjc
Matthew Sparks, MD @Nephro_Sparks
doubt we will see a none versus little study RT @NephRodby: @NephJC that is a remarkable statistic #nephjc
Michelle Rheault @rheault_m
@ansakhuja Maybe 'sepsis' isn't one disorder that needs to be treated with exactly the same fluid regimen for everyone #NephJC
Matthew Sparks, MD @Nephro_Sparks
we need more critical care chats. I like these. invite Ankit more often. #nephjc
Nephrology Journal Club @NephJC
What is the mean hospital length of stay at your institution for sepsis? 7 days for control, 5 for SSSP. #nephjc
Annabel Biruete 🇲🇽 @anniebelch
@Nephro_Sparks #nephjc https://t.co/n6joF1hUVm
Nephrology Journal Club @NephJC
Is the shorter length of stay in protocol group due to excess mortality #Cynic #nephjc
Nephrology Journal Club @NephJC
Last five minutes, final thoughts? #nephjc
Arvind Canchi (Conjeevaram)🇮🇳 @arvindcanchi
@tulunsokit @NephJC Yes that is remarkable. May have something to do with the HIV status. I haven't seen a positive blood culture for TB here either. #Nephjc
Roger Rodby @NephRodby
You have to wonder how many other things we assume are helpful may not be or are even harmful? #nephjc
Nephrology Journal Club @NephJC
RT @NephRodby: You have to wonder how many other things we assume are helpful may not be or are even harmful? #nephjc
Matthew Sparks, MD @Nephro_Sparks
and this is why debates and research will always be needed #NephJC https://t.co/CeeNvYD2ce
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@NephRodby Glass 🥃 is half full or half empty (no pun intended) #NephJC https://t.co/6Lh1lBxNvU
Bea Concepcion @KidneyBea_n
need more studies like this in developing countries. study interventions that are actually available there. #nephjc
Nephrology Journal Club @NephJC
RT @KidneyBea_n: need more studies like this in developing countries. study interventions that are actually available there. #nephjc
Matthew Sparks, MD @Nephro_Sparks
thanks to @ansakhuja for joining. @Errantnephron for writeup and @kidney_boy for moderating. #NephJC I learned that sepsis in Zambia is bad
Bea Concepcion @KidneyBea_n
as a med student in the Philippines, we would always say "ideally..." then would use some other affordable intervention #nephjc
Nephrology Journal Club @NephJC
@Nephro_Sparks @ansakhuja @Errantnephron @kidney_boy sepsis in Detroit is no walk in the park. This disease sucks. #nephjc
Roger Rodby @NephRodby
@tulunsokit @NephJC And to simply something like sepsis into a one fits all goal directed therapy may be pernicious #nephjc
Edgar V. Lerma 🇵🇭 @edgarvlermamd
@NephRodby What to do in the absence of evidence? #NephJC https://t.co/KgoDuBg6hv
Pravir @Proximal_Baxi
Great discussion! thanks to all! #nephjc
Matthew Sparks, MD @Nephro_Sparks
The numbers: 389 Tweets. 56 Participants. October 10th 2017. More #NephJC 📊 here https://t.co/cAxNfYm7XX via @symplur
Roger Rodby @NephRodby
Thanks all, Go Cubs, Go BlackHawks, Bears... glass half full... #nephjc
Nephrology Journal Club @NephJC
@NephRodby and the bulls suck #nephjc
Bea Concepcion @KidneyBea_n
I'm turning my TV off after baseball season RT @NephRodby: Thanks all, Go Cubs, Go BlackHawks, Bears... glass half full... #nephjc
Anupam Singh @anupampom
@NephJC EGDT is a story of medical reversal ..We should take all 'bundled' approaches with pinch of salt #nephjc https://t.co/NDCNkneipL
Roger Rodby @NephRodby
Wow, very telling I didn’t even think to mention the Bulls! Glass empty there, but at least no expectations. #NephJC https://t.co/yGGkK7eglK
AJPMD @pulmccm2016
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Anupam Singh @anupampom
@NephJC A suggested approach to restrictive fluid therapy in septic shock #nephjc https://t.co/IeyDlTBQ7C https://t.co/yVh4kCus0z
Ellen Dawson @elledaws
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
RT @edgarvlermamd: @ansakhuja Comparison of Rivers, ProMISe, ProCESS, ARISE studies #Nephpearls #NephJC https://t.co/YW59P9zlaB
Nephrology Journal Club @NephJC
RT @NephRodby: @tulunsokit @NephJC And to simply something like sepsis into a one fits all goal directed therapy may be pernicious #nephjc
Nephrology Journal Club @NephJC
RT @anupampom: @NephJC EGDT is a story of medical reversal ..We should take all 'bundled' approaches with pinch of salt #nephjc https://t.co/NDCNkneipL
Syed Shahrul Naz @drshahrul80
RT @NephJC: SICK PEOPLE: SICK PEOPLE: Median SBP was 83 mmHg (IQR, 76-87 mm Hg) with a median lactate level of 4.3 mmol/L (IQR, 2.8-7.7 mmol/L). #nephjc
Kevin J. Fowler Principal The Voice of the Patient @gratefull080504
I am attending the Annual Transplant Quality Institute Wed + Thursday too Stay tuned for my tweets! #nephJC @Nephro_Sparks #transplant https://t.co/nMWoF2gj2Q
Matthew Sparks, MD @Nephro_Sparks
RT @gratefull080504: I am attending the Annual Transplant Quality Institute Wed + Thursday too Stay tuned for my tweets! #nephJC @Nephro_Sparks #transplant https://t.co/nMWoF2gj2Q
Aileen Dualan MD @megamomph
You said it! https://t.co/6oapMXMV9C
Sushant Chhabra @sushantdie4u
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Daniel Amador (IM, Neph) @DanielAmador_dr
RT @edgarvlermamd: @ansakhuja Comparison of Rivers, ProMISe, ProCESS, ARISE studies #Nephpearls #NephJC https://t.co/YW59P9zlaB
VICTOR SANNA 🇻🇪 🇳🇬 @VICTORSANNA
RT @gratefull080504: I am attending the Annual Transplant Quality Institute Wed + Thursday too Stay tuned for my tweets! #nephJC @Nephro_Sparks #transplant https://t.co/nMWoF2gj2Q
Neil Floch MD @NeilFlochMD
RT @JHospMedicine: A GIF Is Worth 3000 Words: New #VisualAbstract for #JHMChat: A GIF Is Worth 3000 Words: New #VisualAbstract for #JHMChat: THIS MONDAY 9p ET! @WrayCharles @kidney_boy #nephjc https://t.co/fJSpk1ZhKO https://t.co/zyRDtcLTHL
Dr Mukesh Rulaniya @RulaniyaDr
RT @edgarvlermamd: @srrezaie ✅ The myth of renal dose dopamine #RenalRules #Nephpearls #NephJC 👉🏼 https://t.co/xHHgHoiG2Q https://t.co/39AoW7Z9Fj
Dr Mukesh Rulaniya @RulaniyaDr
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
The Herrick Society @herricksociety
RT @frank_dor:
Dragon Fisting @dragon_fisting
SICK PEOPLE: Median SBP was 83 mmHg (IQR, 76-87 mm Hg) with a median lactate level of 4.3 mmol/L (IQR, 2.8-7.7 mmol/L). #nephjc
David Llantén @d_llanten
RT @hec_310:
Ibrahim Showaihi @showaihi
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Sue G @living_donor
RT @frank_dor:
Ana G. Robles @AnaAGRob
RT @hec_310:
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephRodby: You have to wonder how many other things we assume are helpful may not be or are even harmful? #nephjc
Willij Zuidema @WillijZuidema
RT @frank_dor:
Joel M. Topf, MD FACP @kidney_boy
RT @Nephro_Sparks: thanks to @ansakhuja for joining. @Errantnephron for writeup and @kidney_boy for moderating. #NephJC I learned that sepsis in Zambia is bad
Prof. Dr. Ayhan ÖZHASENEKLER @AOzhasenekler
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Fitz @fpgmanmd
RT @edgarvlermamd: Early Resuscitation Protocol ➡️ In-hospital Mortality in Adults w/ Sepsis & Hypotension 🇿🇲 #NephJC #Nephpearls 👉🏼 https://t.co/C3GbN47L3M https://t.co/64yqVCHUnr
özgür özen @ozgurozen80
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Joel M. Topf, MD FACP @kidney_boy
#NephJC ? https://t.co/wsuDb5hIUF
Ibrahim Shatat @pedsnephrology
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Sidney Erwin Manahan, MD 🇵🇭 @PhRheumaJr
Ideally for (insert intervention). However, due to (finances/ unavailability/ etc) and discussion with pt, will give (alternative int). https://t.co/Z2pyHZTWw5
EVER OLIVIE CIPRIANO @DREVEROLIVIE
RT @edgarvlermamd: Edgar Lerma, 🌧 Chicago-based Nephrologist #NephJC https://t.co/1NawWghiRv
Pano @ED_TRex
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Samir C Gautam @drsamirgautam
RT @edgarvlermamd: Early Resuscitation Protocol ➡️ In-hospital Mortality in Adults w/ Sepsis & Hypotension 🇿🇲 #NephJC #Nephpearls 👉🏼 https://t.co/C3GbN47L3M https://t.co/64yqVCHUnr
American Society of Pediatric Nephrology @ASPNeph
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Taryn Lloyd @JustLloydering
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Austin Jule @AJule450
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Mana @manasigh
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Dr L K Tripathi @lktr18
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Hemachandar @drhemachandarr
RT @anupampom: @NephJC EGDT is a story of medical reversal ..We should take all 'bundled' approaches with pinch of salt #nephjc https://t.co/NDCNkneipL
Andres Cadena @ctropicalis
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
#NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Chris Laing @drchrislaing
Great graphic team. Well done. Surprising results? Maybe needs further validation in other centres? I note 4 litres in fluid protocol https://t.co/T8PFA6my1T
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@drchrislaing Excellent points! There will be a discussion again in about 30 minutes on #NephJC - hope you can join?
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @NephJC: #NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Chris Laing @drchrislaing
RT @hswapnil: @drchrislaing Excellent points! There will be a discussion again in about 30 minutes on #NephJC - hope you can join?
Chris Laing @drchrislaing
Why not https://t.co/ImYwxlhjLz
Nephrology Journal Club @NephJC
Half an hour until #NephJC Take a look at the visual abstract! https://t.co/m0fPgpSdKi
Nephrology Journal Club @NephJC
Join us for the europe/africa edition in 15 minutes?! #NephJC https://t.co/ONS835kC5J
Nathaniel Reisinger @nephrothaniel
RT @NephJC: #NephJC Europe-Africa 8pmBST Fluids in sepsis in Africa - How could you not join? Summary from @errantnephron https://t.co/cySCXGpFjZ
Nephrology Journal Club @NephJC
It’s 8pm GMT - Welcome to #NephJC
Nephrology Journal Club @NephJC
#NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Nephrology Journal Club @NephJC
I’m @drbstewart - Neph/med trainee in Cambridge, UK hosting tonight’s #NephJC
Nephrology Journal Club @NephJC
It can be helpful to use https://t.co/rFoH4MVMzu tchat.io or https://t.co/HkSJU7K32t to tune into #NephJC
Nephrology Journal Club @NephJC
Remember to include #NephJC to every tweet
Nephrology Journal Club @NephJC
Please introduce yourself, any COI, what do you do? #NephJC
Nephrology Journal Club @NephJC
Don't be shy! Even if you are lurking/spectating #NephJC
Nephrology Journal Club @NephJC
Anyone working in Zambia? #NephJC
Nephrology Journal Club @NephJC
Great crowd already! #NephJC
Nephrology Journal Club @NephJC
Stateside had fun with this last night #NephJC
Nephrology Journal Club @NephJC
Tonight we are talking about an RCT of fluid resuscitation in sepsis #NephJC
Nephrology Journal Club @NephJC
@errantnephron has written an excellent summary of the article: https://t.co/cySCXGpFjZ #NephJC
Nephrology Journal Club @NephJC
The paper is available on JAMA https://t.co/XCOazv3Yer #NephJC
Nephrology Journal Club @NephJC
Also shhhh but there may be a link... #NephJC https://t.co/1mHpQxdq4n
Nephrology Journal Club @NephJC
Unfortunately not #openaccess #NephJC
Nephrology Journal Club @NephJC
@Wamugwe @DrMattGB Welcome! #NephJC
Nephrology Journal Club @NephJC
Remember to include #NephJC with every tweet
Nephrology Journal Club @NephJC
Let's get cracking #NephJC
Nephrology Journal Club @NephJC
We’ve been sailing down the EGDT river for a long time - choppy waters recently #NephJC
Nephrology Journal Club @NephJC
3 important trials ProCESS, ARISE and ProMISe from different corners of the globe spelled bad news for EGDT #NephJC https://t.co/cwKwY8r5Fk
Nephrology Journal Club @NephJC
The FEAST study https://t.co/Zqvm9VUbZr argued against fluid boluses in paediatric sepsis. #NephJC
Nephrology Journal Club @NephJC
FEAST was conducted in sub-saharan Africa #NephJC Nice LIFTL review here: https://t.co/wrekz9MyXX
Florian Buchkremer @swissnephro
Hi guys, Florian Buchkremer, no COI, still reading... (thanks, Tom) #NephJC
Nephrology Journal Club @NephJC
@swissnephro Hi! #NephJC
Nephrology Journal Club @NephJC
Total classic amongst clinical trials youtube videos right here: https://t.co/NHYVbmrQkl #NephJC
Nephrology Journal Club @NephJC
#NephJC Great to have you with us https://t.co/HDZlQn75ft
Nephrology Journal Club @NephJC
The venue for this study is Zambia - only 10 ICU beds! #NephJC
Fiona Duthie @faiduthie
Hi, Fiona from Edinburgh, multitasking and haven't read manuscript so mainly lurking! #nephjc
Arkana Laboratories @arkanalabs
RT @NephJC: Tonight we are talking about an RCT of fluid resuscitation in sepsis #NephJC
Nephrology Journal Club @NephJC
So the stage is set for the simplified severe sepsis protocol (SSSP) study #NephJC
Nephrology Journal Club @NephJC
I think we can all agree it’s fantastic work from the investigators and people of Zambia to produce these data #NephJC
Nephrology Journal Club @NephJC
Ok - Let’s crunch the methods and cohort #NephJC
Nephrology Journal Club @NephJC
Study ran oct 2012 to nov 2013 #NephJC
Nephrology Journal Club @NephJC
RT @AKIfellow:
Nephrology Journal Club @NephJC
Included sepsis (infection +>=2SIRS) with SBP<=90 or MAP <=65 #NephJC
Nephrology Journal Club @NephJC
@toates_19 Haha great! #NephJC
Fiona Duthie @faiduthie
@DrMattGB Hmmmmm it got more complicated mid-July..! #nephjc
Nephrology Journal Club @NephJC
They excluded the hypoxic and tachypnoeic #NephJC
Nephrology Journal Club @NephJC
Pretty broad inclusion criteria - agree? #NephJC
Nephrology Journal Club @NephJC
Two arms SSSP (106) vs standard care (103) #NephJC
Nephrology Journal Club @NephJC
Here is the SSSP: #NephJC https://t.co/z9mmdyar3W
Nephrology Journal Club @NephJC
SSSP gives overall 4 litres in five hours 2:1, 2:4 #NephJC
Nephrology Journal Club @NephJC
they clearly recognise this is a fair bit! - screened for overload every hour #goodmedicine #NephJC
Paul Phelan @paulphel
Evening, Paul Phelan, Edinburgh what did I miss? #nephjc
Nephrology Journal Club @NephJC
@paulphel But reflective of their presenting population? #NephJC
Nephrology Journal Club @NephJC
@logiebear111 What’s up with excluding GI bleed without fever? #NephJC
Nephrology Journal Club @NephJC
Fluids were not weight adjusted- no weights in paper #NephJC
Nephrology Journal Club @NephJC
SSSP mandated stopping fluids if JVP>3cm #NephJC
Nephrology Journal Club @NephJC
SSSP stopped fluids if SpO2 fell 3% or RR increased >=5bpm #NephJC
Nephrology Journal Club @NephJC
SSSP also allows for the addition of dopamine for hypotension and transfusion for anaemia #NephJC
Nephrology Journal Club @NephJC
What are your thoughts on dopamine in this mix? #NephJC
Nephrology Journal Club @NephJC
209 patients - mostly HIV+ #NephJC
Nephrology Journal Club @NephJC
These patients were sick - I think we can agree #NephJC
Nephrology Journal Club @NephJC
Sick patients = HIV median CD4 <100 #NephJC
Nephrology Journal Club @NephJC
Sick patients = Positive cultures for TB #NephJC
Nephrology Journal Club @NephJC
Sick patients = Mean Hb 7.8g/dL #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@AKIfellow @Wamugwe @NephJC HIV numbers may not be representative of gen population, but may be of patients with sepsis/shock? #nephjc
Nephrology Journal Club @NephJC
Sick patients = Median alb 2.2g/dl #NephJC
Nephrology Journal Club @NephJC
Sick patients = average lactate >4 #NephJC
Nephrology Journal Club @NephJC
RT @AKIfellow:
Nephrology Journal Club @NephJC
Average age was 36.7 - thoughts on how this shifts things vs other EGDT trials ? #NephJC
Nephrology Journal Club @NephJC
The authors were using the SIRS criteria. This was '12-13 #NephJC
Nephrology Journal Club @NephJC
RT @DrMattGB:
Fiona Duthie @faiduthie
@logiebear111 @NephJC Ditto but better than nothing given resource issue... #nephjc
Nephrology Journal Club @NephJC
Importantly the average IV fluid input over 1st 6h <2l in standard care - too much, too little? #NephJC
Nephrology Journal Club @NephJC
Less than half of standard care grp received any fluid bolus #NephJC
Nephrology Journal Club @NephJC
Very unusual #NephJC https://t.co/oS8zdDgUsa
Nephrology Journal Club @NephJC
Vasopressors in <2% in standard care grp #NephJC
Nephrology Journal Club @NephJC
Not subtle difference in management approach I think we can agree? #NephJC
Nephrology Journal Club @NephJC
@AKIfellow Depends on the clinician's "standard care" #NephJC
Nephrology Journal Club @NephJC
@toates_19 @logiebear111 Or post surgical abdominal sepsis disasters #IBD etc. #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
@drchrislaing Sorry: just tweet with hashtag #NephJC Or go to https://t.co/zpxswszfWz
Nephrology Journal Club @NephJC
@DrMattGB @alehkir Malnourished TB and HIV in the cohort probably doesn't make for a very effective LV #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
#NephJC https://t.co/PANqvFvm4h
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
#NephJC https://t.co/f2UPoXw2Es
Nephrology Journal Club @NephJC
@toates_19 @DrMattGB @AKIfellow Sounds like kwashiorkor territory? #NephJC
Nephrology Journal Club @NephJC
Let’s talk results #NephJC - pretty clear cut!
Nephrology Journal Club @NephJC
Primary outcome was in hospital mortality #NephJC
Nephrology Journal Club @NephJC
Secondary outcome: 28-day mortality and time to death #NephJC
Nephrology Journal Club @NephJC
Bottom line: SSSP does harm - 48% in hospital mortality vs 33% for standard care #NephJC https://t.co/LySmplizbS
Nephrology Journal Club @NephJC
Please tag tweets with #NephJC
Nephrology Journal Club @NephJC
#NephJC https://t.co/T6UwOheJFd
Nephrology Journal Club @NephJC
Bottom line: SSSP does harm - 67% 28 day mortality vs 45% for standard care #NephJC
Nephrology Journal Club @NephJC
Nearly 70% pts died by 28 days! Let that sink in... #NephJC
Nephrology Journal Club @NephJC
Number needed to Harm is 6 for in hospital mortality and 4 for 28 day mortality #NephJC
Nephrology Journal Club @NephJC
Remember: only one patient made it to the ICU #NephJC
Nephrology Journal Club @NephJC
@neilturn @AKIfellow Particularly on the back of mounting (-) literature on EGDT #NephJC
Nephrology Journal Club @NephJC
Anyone willing to trot out reasons why we can ignore these results? #NephJC https://t.co/uXNQktIHR3
Nephrology Journal Club @NephJC
Is this harm all down to mostly volume? mostly dopamine? cocktail? Something great in standard care? #NephJC
Nephrology Journal Club @NephJC
#NephJC https://t.co/IE1nI5CwQ7
Nephrology Journal Club @NephJC
@AKIfellow @Dr_Beale_ @neilturn Tyranny of distance also #NephJC
Nephrology Journal Club @NephJC
Results in full detail - pretty clear evidence of harm overall #NephJC https://t.co/jBG6jUvvtk
Nephrology Journal Club @NephJC
K-M curve tells story of 2ndry endpoint #NephJC https://t.co/vHncQWbPQt
Fiona Duthie @faiduthie
@logiebear111 @toates_19 @NephJC Pulmonary oedema or ARDS? Anyone know if ards is less common in hiv given it's an inflammatory illness..? Maybe not the issue... #nephjc
Nephrology Journal Club @NephJC
Single centre - #FEAST went all over SSafrica ... would the results have changed? #NephJC
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @neilturn:
Nephrology Journal Club @NephJC
@toates_19 With albumin that low, there's rationale for giving fluid that stays put? #NephJC
Nephrology Journal Club @NephJC
If you designed this study - what other end points would you want to include? #NephJC
Chris Laing @drchrislaing
#nephjc 4 litres seems a lot
Nephrology Journal Club @NephJC
SSSP gives overall 4 litres in five hours 2:1, 2:4 #NephJC https://t.co/fYcydcrC2r
Nephrology Journal Club @NephJC
Ok 10 minutes left - Any further ideas about where the paper leaves us? #NephJC
Nephrology Journal Club @NephJC
#NephJC how will this change your management?
Nephrology Journal Club @NephJC
Will you be "keeping 'em dry"? #NephJC https://t.co/WOZJZ8mroL
Chris Laing @drchrislaing
#nephjc none of the major GDT NEJM trials have reduced severe AKI rates. I guess what is surprising here is adverse outcome?
Nephrology Journal Club @NephJC
@WhistlingDixie4 thanks for joining! See you again #NephJC
Chris Laing @drchrislaing
#nephjc @toates_19 like many things in life with fluids "timing is everything"
Nephrology Journal Club @NephJC
@toates_19 Fluids = drugs with benefits and harms #NephJC (though not really any benefits here!)
Nephrology Journal Club @NephJC
Any final ideas about this paper? #NephJC
Dr. HattaN BojaN I د. هتان بوجان @hattanbojan
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Nephrology Journal Club @NephJC
About time to draw to close - Thanks all for joining in - really enjoyed this #NephJC chat!
Nephrology Journal Club @NephJC
Absolutely this should be #openaccess #NephJC https://t.co/MezbddTSSi
Nephrology Journal Club @NephJC
Thanks for joining this #NephJC - this is @drbstewart signing off!
Chris Laing @drchrislaing
#nephjc don't forget with the big sepsis GDT trials "standard care" was not unrecognised sepsis/no action. Lack of evidence is around GDT
Chris Laing @drchrislaing
Another great graphic from the #NephJC team https://t.co/LEPf2q7LbT
Matthew Sparks, MD @Nephro_Sparks
RT @NephJC: #NephJC Oct 10/11 The article: https://t.co/XCOazv3Yer The summary: https://t.co/cySCXGpFjZ #VisualAbstract https://t.co/HyWGVZUC82
Swapnil Hiremath @hswapnil@bsky.social @hswapnil
RT @neilturn:
Matthew Sparks, MD @Nephro_Sparks
fantastic stuff #NephJC https://t.co/R5HMQXVkDw
Gail Rae-Garwood @Slowitdownckd
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Michelle Rheault @rheault_m
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Jerad Gardner, MD @JMGardnerMD
RT @NephJC: #NephJC is the twitter journal club for Nephrology. And it's actually brilliant, if we say so ourselves.
Jerad Gardner, MD @JMGardnerMD
#NephJC was a major inspiration for #pathJC. Our neph colleagues helped us a lot when starting the #pathology Twitter journal club! https://t.co/ghv5YkTxsx
YNP of ERA @ynptweets
RT @NephJC: I love me some Table 1! #NephJC https://t.co/zGBSQI0drS
YNP of ERA @ynptweets
RT @drchrislaing: Another great graphic from the #NephJC team https://t.co/LEPf2q7LbT
Sibel Gokcay Bek @sibgokcay
RT @NephJC: #NephJC chat tonight/tomorrow Summary: https://t.co/NAbvetvGSo Full text: https://t.co/lFTvhvOign #VisualAbstract : https://t.co/mHEtv2QYnr
Martín Vargas 🇲🇽 @MartinVargas89
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
MJ (Marietjie) Slabbert Keilty 🚁 🐈‍⬛ @Gas_Air_CCdoc
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Natalie Lavergne @LavergneNatalie
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
John P Erwin III MD FACC @HeartOTXHeartMD
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Dr.Carlos Fernandez Pereira @dr_cfp
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
Jonathan Britton @JonTheMedic
RT @edgarvlermamd: ICU Nephrology: ICU Nephrology: Quick reference for DOSING OF PRESSORS from @srrezaie #Nephpearls #NephJC https://t.co/v1oxvtC0LB
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