#NephJC Transcript

Healthcare social media transcript of the #NephJC hashtag.
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Joel Topf, MD FACP @kidney_boy
#VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome #BetterTogether https://t.co/p6AwF0C8nh
Swapnil Hiremath, MD, MPH @hswapnil
RT @kidney_boy: #VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome…
Daniel Coyne @DrDanMO
RT @kidney_boy: #VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome…
Manuel Marquez 👨🏻‍⚕️🚰🇲🇽 @Kidney_Power
RT @kidney_boy: #VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome…
Joel Topf, MD FACP @kidney_boy
#VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Anthony Provenzano @docpro89
RT @kidney_boy: #VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome…
James C. Fletcher, MD @jfletchermd
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Nephrology Jrnl Club @NephJC
Reminder: #NephJC at 8 pm BST today & again 9 pm Eastern tonight Not too late to get the summary: https://t.co/EKer0BjMf4
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: Reminder: #NephJC at 8 pm BST today & again 9 pm Eastern tonight Not too late to get the summary: https://t.co/EKer0BjMf4
Dina Nilasari @drdina_nilasari
RT @kidney_boy: #VisualAbstract Release candidate 1 for today's #NephJC on itching. 8pm BST and 9pm EST. Feedback welcome…
Nephrology Jrnl Club @NephJC
Don’t forget in half an hour #NephJC 8pm BST #visualabstract https://t.co/erdBavy1n6
Nephrology Jrnl Club @NephJC
It's 8pm Wednesday. Let’s get this chat started. Welcome everybody!!! #nephjc
Fra Ian 🇪🇺 @caioqualunque
RT @NephJC: Don’t forget in half an hour #NephJC 8pm BST #visualabstract https://t.co/erdBavy1n6
Nephrology Jrnl Club @NephJC
Tonight's #NephJC is A Systematic Review on the treatment of #uremic #pruritus #openaccess https://t.co/Sp6IqK7iPE #nephjc
Nephrology Jrnl Club @NephJC
Check the summary by @DoctorGates https://t.co/EKer0BjMf4 & @paulphel https://t.co/yaw3yMw6uK #nephjc
Nephrology Jrnl Club @NephJC
My name is Omar Taco @errantnephron; today I will be your host. I’m a #NSMC intern & a nephrologist from Barcelona #nephjc
Fra Ian 🇪🇺 @caioqualunque
I’ll join #NephJC later...
Nephrology Jrnl Club @NephJC
@caioqualunque Ciao!, you're always welcomed #nephjc
Nephrology Jrnl Club @NephJC
Please say hello, introduce yourself and declare any conflicts of interest #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
Swapnil Hiremath, from @OttawaHospital Lurking from in between meetings today #NephJC https://t.co/oQ7dfdL7EP
Nephrology Jrnl Club @NephJC
@hswapnil Hola!, nice to see you #nephjc
Nephrology Jrnl Club @NephJC
Don't forget to add #NephJC to every tweet. You want to be part of the discussion and part of the recorded journal club :)
Silvi Shah, MD, MS @silvishah
Hi this is Silvi from Cincinnati. #nephJC
Tom Oates @toates_19
Hi Tom just checking in, won't be able to join though! #NephJC
Nephrology Jrnl Club @NephJC
@silvishah Hey Silvi, thanks for making it! #nephjc
Rob Peel @rabpeel
Rob from a dark and windy Highland Scotland #nephjc
Nephrology Jrnl Club @NephJC
@toates_19 Great to see you, eventhough lurking #nephjc
Benjamin Stewart @drbstewart
#NephJC Ben - Jnr doc from Cambridge. Intermittently lurking! https://t.co/toMuYVD4Up
Matt Sparks @Nephro_Sparks
This is Matt Sparks, @DukeKidney APD itching to join :) #nephjc
Nephrology Jrnl Club @NephJC
@rabpeel Here on duty and in sunny BCN #nephjc
Matt Sparks @Nephro_Sparks
@rabpeel Hi Rob #nephjc
Nephrology Jrnl Club @NephJC
@drbstewart Thank you for joining Ben ! #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
I found those first-person account from @heartofengland very compelling https://t.co/86AxUBnoaT #nephjc
Matt Sparks @Nephro_Sparks
@drbstewart Hi Benjamin #nephjc
Nephrology Jrnl Club @NephJC
To follow the chat, we recommend https://t.co/SEeRXFHE9J or TChat.io; Here a how to guide: https://t.co/5jPXTxjUUZ #nephjc
Gates Colbert, MD @DoctorGates
Dallas Nephrologist. #NSMC 2017. Host of the North American chat at 9pm EST. Looking forward to this preview session and the our International colleagues' experiences. #nephjc
Bea Concepcion @KidneyBea_n
Bea Concepcion @VUMCKidney #NSMC 2017, No COI #NephJC
Matt Sparks @Nephro_Sparks
@KidneyBea_n Hi Bea #nephjc
Nephrology Jrnl Club @NephJC
@KidneyBea_n Bea, nice to see u! #nephjc
Matt Sparks @Nephro_Sparks
Omar is in the house tonight #nephjc
Nephrology Jrnl Club @NephJC
Also remember that The NephJC Kidneys...They're back, we're collecting nominations https://t.co/2WXFdGVztt #nephjc
Matt Sparks @Nephro_Sparks
#NephJCKidneys #nephjc
Bea Concepcion @KidneyBea_n
RT @Nephro_Sparks: Omar is in the house tonight #nephjc
Nephrology Jrnl Club @NephJC
T0: To kick off, what is your most used therapy for #itching? #nephjc
Ross Morton @signindoc
#NephJC lurking in New Brunswick
Matt Sparks @Nephro_Sparks
nice summary from @DoctorGates #280 #NephJC
Swapnil Hiremath, MD, MPH @hswapnil
Showing off! #280character #NephJC https://t.co/OVEHkIdpLd
Matt Sparks @Nephro_Sparks
RT @DoctorGates: Dallas Nephrologist. #NSMC 2017. Host of the North American chat at 9pm EST. Looking forward to this preview sess…
Bea Concepcion @KidneyBea_n
RT @NephJC: The summary for the next #NephJC from @DoctorGates is up: https://t.co/RNN76b1iJB #pruritis #nephjc
Carlo Alfieri @carlo_alfieri
Goodevening #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
T0: start off with Vaseline; camphor/menthol/steroid combo cream; then gabapentin. #nephjc
Nephrology Jrnl Club @NephJC
@carlo_alfieri Good evening Carlo! #nephjc
Alexander Kirsch @alehkir
Alex Kirsch, Graz, Austria; no COI, mostly lurking; #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: T0: To kick off, what is your most used therapy for #itching? #nephjc
Nephrology Jrnl Club @NephJC
Any particular indications for prescribing one or the other? #nephjc
Matt Sparks @Nephro_Sparks
honestly not much experience with itching. generous use of moisturizers #worked #nephjc
Rob Peel @rabpeel
T0 moisturisers then menthol in aqueous- before moving on to systemic medication #nephjc
Rob Peel @rabpeel
T0 make sure they are iron repleat #nephjc
Alexander Kirsch @alehkir
starting with local: first rehydrating, then sometimes steroids; very frequently quickly moving on to gabapentin; Kt/V tuning #nephjc
Carlo Alfieri @carlo_alfieri
#nephjc Sorry i am new in trying to understand how it works
Fra Ian 🇪🇺 @caioqualunque
T0: primerose oil and generous scrub during showers #NephJC
Nephrology Jrnl Club @NephJC
They included studies using this validated pruritus scales, do you use them for treatment guidance ? https://t.co/OwmRRizi7Y #nephjc https://t.co/kI1b71OrBf
Alexander Kirsch @alehkir
@NephJC skin appearance?! if dry/flaky then more likely to give moisturizer a chance.. #nephjc
Matt Graham-Brown @DrMattGB
Sorry late, Matt GB. With fever, (man flu I'm sure). No COI #NephJC
Nephrology Jrnl Club @NephJC
@rabpeel Interesting... could you expand on that? #nephjc
Alexander Kirsch @alehkir
@carlo_alfieri I've been tagging along for a year now and still don't get the "T0", "T1" story! #nephjc
Marisol @mary880307
Hola soy Marisol. De Toluca, México. Soy residente de nefrología. https://t.co/gsLv7z8lh1
Alexander Kirsch @alehkir
@NephJC frankly: no. seems like by the time we're told it's very bothersome. probably should have more structured screening/questioning! #nephjc
Matt Graham-Brown @DrMattGB
Gabapentin/pregabelin ~ 30% experiencing side effects that preclude use. If skin dry then liberal emollient, too, not instead/before #nephjc https://t.co/TkxVb27v98
Michelle Rheault @rheault_m
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Nephrology Jrnl Club @NephJC
Pretty interesting everybody give moisturizers, and nobody talk about optimal dialysis or HPT, P & Mg ;) #nephjc
Matt Graham-Brown @DrMattGB
@NephJC Don't feel the need in clinical practice. 'Do you itch?' 'Do you want to try a treatment?' Seems to work well! #nephjc
Rob Peel @rabpeel
@NephJC I like the idea #NephJC
Rob Peel @rabpeel
@NephJC Phos and PTH v difficult to fix in most #nephjc
Matt Graham-Brown @DrMattGB
@rabpeel @NephJC Good for research to grade effectiveness. In clinic pt will tell you if a treatment has helped or not. That's all you need #nephJC
Alexander Kirsch @alehkir
@NephJC it's what I meant with Kt/V tuning :) #nephjc
Nephrology Jrnl Club @NephJC
T1: Let’s talk about the methods do u like it being a Systematic Review or you would have loved a Meta-Analysis? #nephjc
Nephrology Jrnl Club @NephJC
It was a systematic review limited to RCT of CKD stage 3 or higher, comparing any intervention vs placebo... thoughts #nephjc
Nephrology Jrnl Club @NephJC
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Matt Graham-Brown @DrMattGB
@alehkir @NephJC Do you find it helps at all. My experience (and data) suggest if Kt/V around 1.5 the. No help to increasing #nephjc
Bea Concepcion @KidneyBea_n
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/NaX3e902nN
Alexander Kirsch @alehkir
@NephJC don't think I have seen uremic pruritus in CKD <4... #nephjc
Nephrology Jrnl Club @NephJC
@alehkir True that, it should be a stepwise approach #Nephjc
Rob Peel @rabpeel
under dialysis rare in our unit #nephjc
Nephrology Jrnl Club @NephJC
RT @DrMattGB: @alehkir @NephJC Do you find it helps at all. My experience (and data) suggest if Kt/V around 1.5 the. No help to increasing…
Matt Graham-Brown @DrMattGB
@NephJC Quality of studies not great and high risk of bias, so personally happy with S/R to synthesise a narrative and inform big trials #nephjc
Rob Peel @rabpeel
I like the limiting to placebo studies #nephjc
Fra Ian 🇪🇺 @caioqualunque
@NephJC The quality of intervention should be based on pt-reported outcomes: VAS makes little/no sense.I'd like to sleep but pruritus... #NephJC
Alexander Kirsch @alehkir
@DrMattGB @NephJC Agree. If you look at UpToDate they even claim that itching may be symptom of too high Kt/V⁉️ haven't read the paper they cite. #nephjc
Matt Graham-Brown @DrMattGB
@alehkir @NephJC Yep, same - except in very elderly where it may well 'just' be 'senile' (don't like the term) pruritis #nephjc
Fra Ian 🇪🇺 @caioqualunque
I agree... Pruritus is a common symptom among the elders: inclusion of ckd3 is a potential confounder #nephJC https://t.co/FmGBTSwQuW
Nephrology Jrnl Club @NephJC
@rabpeel I like the wide range of treatments with RCTs & the validated scales #nephjc
Matt Graham-Brown @DrMattGB
Yes #nephjc https://t.co/F83DeAU3FY
Matt Graham-Brown @DrMattGB
RT @KidneyBea_n: RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/NaX3…
Silvia Villarroel @silviacv_
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Alexander Kirsch @alehkir
@rabpeel same here. and if there is, usually increase in HD time only option because other options (BF, dialyzer surface etc) already ✅ #nephjc
Silvi Shah, MD, MS @silvishah
@NephJC Meta analysis can be argued for more evidence based than a review #NephJC
Nephrology Jrnl Club @NephJC
@caioqualunque Bias everywhere that's why they used The PRISMA checklist https://t.co/e2KmTFwWLg #nephjc
Matt Graham-Brown @DrMattGB
@alehkir @NephJC https://t.co/mHuK2l8pHN https://t.co/UKeKwYOcPx #nephjc
Nephrology Jrnl Club @NephJC
RT @rabpeel: I like the limiting to placebo studies #nephjc
Alexander Kirsch @alehkir
does anyone change dialyzer if intractable itching persits despite the above mentioned options? #nephjc
Nephrology Jrnl Club @NephJC
@DrMattGB Thanks Matt! #nephjc
Matt Graham-Brown @DrMattGB
@silvishah @NephJC Yep, but only if quality and of evidence good enough. I think there would have been limited value in meta-analysis of these data #nephjc
Nephrology Jrnl Club @NephJC
@alehkir There is always a temptation of "if no evidence, identify the most "effective" treatment for an individual patient #nephjc
Fra Ian 🇪🇺 @caioqualunque
Phototherapy is often the last resource, but I've seen impressive and persistent results. Anti-H1 are overused and overrated #nephjc https://t.co/8sGoYZSCej
Nephrology Jrnl Club @NephJC
This is something the paper explains optimal therapy is uncertain, therefore there is justification to try different therapy options #nephjc
Matt Graham-Brown @DrMattGB
@alehkir Yes, good point. polyarylethersulfone tend to cause more itch (in my experience) and switching to a polysulfone can help #nephjc
Nephrology Jrnl Club @NephJC
RT @DrMattGB: @alehkir Yes, good point. polyarylethersulfone tend to cause more itch (in my experience) and switching to a polysulfone can…
Nephrology Jrnl Club @NephJC
As they portrayed a "N-1" study sometimes is needed, a valid point? #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
@alehkir I have done (changed dialysers) - but usually doesn't help... #nephjc
Matt Graham-Brown @DrMattGB
@caioqualunque Prescribed PUVA or PUVB? #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: This is something the paper explains optimal therapy is uncertain, therefore there is justification to try different therapy op…
Fra Ian 🇪🇺 @caioqualunque
@DrMattGB @alehkir That's absolutely true, but formally this dialysis-related pruritus not uremic pruritus #nephJC
Nephrology Jrnl Club @NephJC
RT @DrMattGB: @caioqualunque Prescribed PUVA or PUVB? #nephjc
Nephrology Jrnl Club @NephJC
@DrMattGB No experience on that, myself #nephjc
Thalakunte Muniraju @thalakunte
RT @NephJC: @alehkir There is always a temptation of "if no evidence, identify the most "effective" treatment for an individual patient #n
Alexander Kirsch @alehkir
@DrMattGB good point! what about switching to HDF if not already on HDF? #nephjc
Matt Graham-Brown @DrMattGB
NB this is true for an allergic phenomenon where eosinophils often a bit up etc. For most changing dialyser not helpful #nephjc https://t.co/uZYy710kLh
Matt Graham-Brown @DrMattGB
@caioqualunque @alehkir Yes, agree - see my quotes tweet! #nephjc
Matt Sparks @Nephro_Sparks
@Kimmyrocks47Kim yes. that is first maneuver for me as well #nephjc
Fra Ian 🇪🇺 @caioqualunque
@DrMattGB PUVA #nephjc
Matt Graham-Brown @DrMattGB
@alehkir Never found it useful, and studies don't show (great) benefit. I believe UP is mediated through CNS, hence gabapentin etc effective #nephjc
Carlo Alfieri @carlo_alfieri
#nephjc in my department we have switched somebody to hdf with some good results
Rob Peel @rabpeel
PUVB is better I think #nephjc
Matt Graham-Brown @DrMattGB
@alehkir Personally I think it's the hypocretin / orexin pathways +/- 'uraemic' insults to PNS #nephjc - all conjecture of course
Carlo Alfieri @carlo_alfieri
#nephjc I never used it! Nowadays I am working in kidney transplantation
Navdeep Tangri @NavTangri
RT @KidneyBea_n: RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/NaX3…
Alexander Kirsch @alehkir
@Nephro_Sparks @Kimmyrocks47Kim agree, yet a very challenging maneuver! #nephjc
Carlo Alfieri @carlo_alfieri
What about anti histaminic drugs? #nephjc
Nephrology Jrnl Club @NephJC
@rabpeel UVB therapy is associated with carcinogenesis risk & should not be used in patients on immunosuppressive therapy #nephjc
Nephrology Jrnl Club @NephJC
What I take from the study is that w/the exception of gabapentin, the current evidence for all other treatments is weak #nephjc
Alexander Kirsch @alehkir
@carlo_alfieri haven't had a lot of success with those. #nephjc
Matt Graham-Brown @DrMattGB
@Nephro_Sparks @Kimmyrocks47Kim If Phos very high, sure it will help. If modestly up (above normal range) then not associated with UP https://t.co/bUAPmsSZqm #nephjc
Rob Peel @rabpeel
@NephJC most of my dialysis patients not immune suppressed and not on list- only used in v rare cases #nephjc
Nephrology Jrnl Club @NephJC
Any other thoughts after reading this systematic review... please share! #nephjc
Matt Graham-Brown @DrMattGB
@alehkir @carlo_alfieri Agree and no evidence they work for UP #nephjc
Fra Ian 🇪🇺 @caioqualunque
@rabpeel I don't know... Anyway in Italy you need a dermatologist consult with a specific request for phototherapy prescription #nephjc
Matt Sparks @Nephro_Sparks
RT @DrMattGB: @Nephro_Sparks @Kimmyrocks47Kim If Phos very high, sure it will help. If modestly up (above normal range) then not…
Matt Graham-Brown @DrMattGB
Same in U.K. #nephjc https://t.co/oaPKdE6EBh
Carlo Alfieri @carlo_alfieri
I am sorry but I arrived late: could you indicate the extreme of the review? #nephjc
Carlo Alfieri @carlo_alfieri
@rabpeel I totally agree with you #nephjc
Fra Ian 🇪🇺 @caioqualunque
@DrMattGB @alehkir @carlo_alfieri Anyway, if you use an anti-h1, what's your first choice drug? #nephjc A lot of cetirizine here
Matt Graham-Brown @DrMattGB
Need better data. GABA & pregabalin seem the best options if don't get SEs. Don't be afraid to ask for a dermatologist's help! #nephjc https://t.co/hhtPVj8du1
Hector Palmett @hectpari
RT @NephJC: Don't forget to add #NephJC to every tweet. You want to be part of the discussion and part of the recorded journal club :)
Carlo Alfieri @carlo_alfieri
Yes absolutely citorizine also in Italy! #nephjc
Fra Ian 🇪🇺 @caioqualunque
@carlo_alfieri here's the paper #nephJC https://t.co/3UD3Qac05d
Nephrology Jrnl Club @NephJC
Well guys this has been a terrific experience btw calls/hosting! #nephjc
Nephrology Jrnl Club @NephJC
Remember to nominate fo The NephJC Kidneys...https://t.co/2WXFdGVztt #NephJCKidneys. #nephjc
Nephrology Jrnl Club @NephJC
Remember to sign up for the NephJC once a week (or less) newsletter and follow us on twitter. #NephJC https://t.co/5aumn8ImwF
Matt Graham-Brown @DrMattGB
@caioqualunque @alehkir @carlo_alfieri I don't prescribe them for UP - though I accept I may be an extreme phenotype! #NephJC
Matt Graham-Brown @DrMattGB
@NephJC Well done @Errantnephron - good work! Nice chat all, thanks #nephjc
Fra Ian 🇪🇺 @caioqualunque
RT @NephJC: Remember to nominate fo The NephJC Kidneys...https://t.co/2WXFdGVztt #NephJCKidneys. #nephjc
Rob Peel @rabpeel
thank you all #nephjc
Nephrology Jrnl Club @NephJC
Remember one of the core goals of #NephJC is to build a personal learning network, so make sure you hit the follow button often!
Nephrology Jrnl Club @NephJC
Great newcomers are welcome and invited as always!, I have to check some dialysis patients!, Thanks to all! #nephjc
Carlo Alfieri @carlo_alfieri
Thank you very much! Next time I'll be more ready! #nephjc
Nephrology Jrnl Club @NephJC
This is @errantnephron saying Buenas noches! (Good night!) #nephjc
Swapnil Hiremath, MD, MPH @hswapnil
@DrMattGB @caioqualunque @alehkir @carlo_alfieri Same here. Don't work, sedative...#NephJC
Fra Ian 🇪🇺 @caioqualunque
@NephJC Great work, Omar. I am sure I'll see you later at the #nephjc after-party... I mean tonight #glomcon chat 🤓👍☕️
Matt Graham-Brown @DrMattGB
RT @NephJC: Remember to nominate fo The NephJC Kidneys...https://t.co/2WXFdGVztt #NephJCKidneys. #nephjc
Alexander Kirsch @alehkir
Thanks to all! going to read up on orexin now. #nephjc
Thalakunte Muniraju @thalakunte
Thank you #NephJC
Jyoti Baharani @renalpages
RT @kidney_boy: #VisualAbstract Release candidate 2 for today's #NephJC on itching. 8pm BST and 9pm EST. https://t.co/jjJIUppVzQ
Nephrology Jrnl Club @NephJC
The numbers: 183 Tweets. 34 Participants. 529,315 Impressions. September 26th 2017. More #NephJC 📊 here https://t.co/lnOTUr5y9E
Fra Ian 🇪🇺 @caioqualunque
RT @NephJC: The numbers: 183 Tweets. 34 Participants. 529,315 Impressions. September 26th 2017. More #NephJC 📊 here https://t.co/lnOTUr5y9E
Swapnil Hiremath, MD, MPH @hswapnil
RT @NephJC: The numbers: 183 Tweets. 34 Participants. 529,315 Impressions. September 26th 2017. More #NephJC 📊 here https://t.co/lnOTUr5y9E
#NephJC content from Twitter.